4-Phenyl-2-butanol Property

Melting point:

61 °C

Boiling point:

132 °C/14 mmHg (lit.)

Density 

0.970 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.5140(lit.)

FEMA 

2879 | 4-PHENYL-2-BUTANOL

Flash point:

231 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Almost insoluble in water, soluble in alcohol and oils

pka

15.10±0.20(Predicted)

form 

liquid

color 

Colorless

Odor

at 100.00 %. floral peony foliage sweet mimosa heliotrope

Odor Type

floral

JECFA Number

815

BRN 

1908294

LogP

2.23

CAS DataBase Reference

2344-70-9(CAS DataBase Reference)

NIST Chemistry Reference

4-Phenyl-2-butanol(2344-70-9)

Safety

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29062900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

4-Phenyl-2-butanol Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Chemical Properties

4-Phenyl-2-butanol has a herbaceous, aromatic, floral-fruity odor.

Uses

4-Phenyl-2-butanol is a reagent used for the direct alkylation of amines with primary and secondary alcohols through biocatalytic hydrogen borrowing. It is also used in the preparation of personal care composition comprising malodor reduction compositions.

Preparation

The optically inactive product can be prepared by hydrogenation of benzylidene acetone in alcohol solution; under pressure in the presence of platinum oxide, palladium oxide or ferrous sulfate; by reduction with magnesium in methanol.

Synthesis Reference(s)

Tetrahedron Letters, 30, p. 6461, 1989 DOI: 10.1016/S0040-4039(01)88994-2

General Description

4-Phenyl-2-butanol undergoes (η⁵-pentaphenylcyclopentadienyl)RuCl(CO)₂ catalyzed racemization efficiently at room temperature in the presence of a base. 4-Phenyl-2-butanol on reaction with sulfuric acid yields polymer.