8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate
- Product Name
- 8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate
- CAS No.
- 264622-58-4
- Chemical Name
- 8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate
- Synonyms
- MRS 1754 hydrate;MRS1754;MRS-1754;MRS 1754;Adenosine Receptor,MRS-1754,Inhibitor,MRS 1754,P1 receptor,MRS1754,inhibit;N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide;8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate;N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy]acetaMide;N-(4-Cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide;AcetaMide,N-(4-cyanophenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-;AcetaMide, N-(4-cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-
- CBNumber
- CB62098696
- Molecular Formula
- C26H26N6O4
- Formula Weight
- 486.52
- MOL File
- 264622-58-4.mol
8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Property
- Density
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- DMSO: soluble >10mg/mL
- pka
- 8.24±0.70(Predicted)
- form
- solid
- color
- off-white
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H290May be corrosive to metals
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P234Keep only in original container.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363Wash contaminated clothing before reuse.
P390Absorb spillage to prevent material damage.
P405Store locked up.
P406Store in corrosive resistant/… container with a resistant inner liner.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M6316
- Product name
- MRS 1754 hydrate
- Purity
- ≥98% (HPLC), solid
- Packaging
- 5mg
- Price
- $265
- Updated
- 2024/03/01
- Product number
- M6316
- Product name
- MRS 1754 hydrate
- Purity
- ≥98% (HPLC), solid
- Packaging
- 25mg
- Price
- $837
- Updated
- 2024/03/01
- Product number
- M750243
- Product name
- MRS1754
- Packaging
- 1mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- CS-0003210
- Product name
- MRS1754
- Purity
- 98.31%
- Packaging
- 5mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- CS-0003210
- Product name
- MRS1754
- Purity
- 98.31%
- Packaging
- 10mg
- Price
- $190
- Updated
- 2021/12/16
8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Chemical Properties,Usage,Production
Uses
MRS 1754 acts as an adenosine receptor antagonist which displays bronchospasmolytic activity, applicable to treatments involving respiratory disorders.
Definition
ChEBI: N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide is an oxopurine.
Biological Activity
Selective adenosine A 2B receptor antagonist (K i values are 1.97, 16.8, 403, 503, 570 and 612 nM for hA 2B , rA 1 , hA 1 , hA 2A , hA 3 and rA 2A receptors respectively).
Biochem/physiol Actions
MRS 1754 hydrate is a p-cyanoanilide xanthine derivative. It might act as a potential anti-asthmatic drug.
storage
Desiccate at RT
8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
8-[4-[((4-Cyanophenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine hydrate Suppliers
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- Country
- Switzerland
- ProdList
- 6896
- Advantage
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