ChemicalBook > CAS DataBase List > 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

Product Name
5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid
CAS No.
74936-72-4
Chemical Name
5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid
Synonyms
PRAN-001;278-034-2;Le Chi Chi;1,4-DHPCOOH;UNII:5DU0E310OI;Nicardipine USP RC A;Nifedipine Impurity 2;Le Chi mother nucleus;Lercanidipine nucleus;Lercanidipine mainring
CBNumber
CB62129651
Molecular Formula
C16H16N2O6
Formula Weight
332.31
MOL File
74936-72-4.mol
More
Less

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid Property

Melting point:
200-202?C
Boiling point:
505.0±50.0 °C(Predicted)
Density 
1.345±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Sparingly), Methanol (Slightly, Heated)
form 
Solid
pka
1.66±0.70(Predicted)
color 
Pale Yellow to Light Yellow
More
Less

Safety

HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
M2493
Product name
Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$36
Updated
2024/03/01
TCI Chemical
Product number
M2493
Product name
Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$109
Updated
2024/03/01
TRC
Product number
D449123
Product name
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicAcid3-MethylEster
Packaging
10g
Price
$945
Updated
2021/12/16
Matrix Scientific
Product number
090670
Product name
5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid
Purity
95+%
Packaging
5g
Price
$1418
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0006136
Product name
1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID 3-METHYLESTER
Purity
95.00%
Packaging
1G
Price
$1871.1
Updated
2021/12/16
More
Less

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid Chemical Properties,Usage,Production

Description

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid(1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester) is a pharmaceutical intermediate ingredient used in the preparation of Barnidipine, Lercanidipine hydrochloride and nitrendipine analogues. These drugs are all calcium channel blockers and are used to treat various forms of hypertension.

Chemical Properties

Light-Yellow Solid

Uses

1,4-Dihydropyridine derivative used in the prevention and therapy of atherosclerotic degradation of arterial walls. Nicardipine USP Related Compound A.

Uses

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester can be used in the prevention and therapy of atherosclerotic degradation of arterial walls.

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Key Organics Ltd.
Tel
--
Fax
--
Email
info@keyorganics.net
Country
United Kingdom
ProdList
6741
Advantage
50
More
Less

View Lastest Price from 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid manufacturers

Xuchang Hengsheng Pharmaceutical Co., Ltd
Product
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester 74936-72-4
Price
US $0.00/Kg
Min. Order
1Kg
Purity
≥99.0%
Supply Ability
10 Tons
Release date
2024-08-07
Guangzhou PI PI BIOTECH INC
Product
Nifedipine Impurity2
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2020-06-18
TAIZHOU DKD CHEMICAL CO., LTD.
Product
3,5-Pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl ester 74936-72-4
Price
US $100.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5tons
Release date
2022-11-01

74936-72-4, 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acidRelated Search:


  • 2,6-DIMETHYL-5-METHOXY CARBONYL-4-(3-NITRO-PHENYL)-1,4-DIHYDROPYRIDINE-3-CARBOXYLIC ACID
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
  • Lercanidipine mainring
  • rac-1,4-Dihydro-5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic Acid
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-methyl ester
  • 2,6-DiMethyl-5-Methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydorpyridine-3-carboxylic acid
  • Methyl hydrogen 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
  • 2,6-dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydroxypyridine-3-carboxylic acid
  • Nicardipine Carboxylic Acid Derivative (Nifedipine Impurity 2)
  • Nimodipine Impurity 7
  • Nicardipine USP RC A
  • Lercanidipine Impurity 9
  • Le Chi Chi
  • 278-034-2
  • 2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
  • Nicardipine USP Related Compound A
  • PRAN-001
  • 1,4-Dihydro-2,6-diMethyl-4-(3-nitrophenyl)-3,5-pyr
  • 1,4-DHPCOOH
  • 1,4-DIHYDRO-5-METHOXYCARBONYL-2,6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3-CARBOXYLIC AC
  • 2,6-DI-ME-4-(3-NITRO-PH)-1,4-2H-PYRIDINE-3,5-DICAR
  • Nicardipine Carboxylic Acid Derivative
  • Nifedipine Impurity 2
  • Le Chi mother nucleus
  • Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
  • Nifedipine Impurity 2 (Nicardipine Carboxylic Acid Derivative )
  • 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl ester
  • Lercanidipine nucleus
  • -1,4-dihydropyridine-3-carboxylic acid
  • -2,6-dimethyl-4-(3-nitrophenyl)
  • PHARMACEUTICAL RAW MATERIAL : 2,6-DIMETHYL-5-METHOXYCARBONYL-4-(3-NITROPHENYL)-1,4- DIHYDROPYRIDINE -3- CARBOXYLIC ACID
  • Benidipine Impurity 18
  • Le Cardipine Main Ring Reference
  • 2,6-dimethyl-5-methoxycarbonyl-4-(3-nitro phenyl)-1,4 dihydropyridine-3-carboxylic acid (74936-72-4)
  • Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate &gt
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitro
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
  • Benidipine Intermediate
  • Nicardipine Related Compound A (Nicardipine Carboxylic Acid Impurity)
  • 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)...
  • Nicardipine Impurity88
  • Nicardipine Carboxylic acid DerivativeQ: What is Nicardipine Carboxylic acid Derivative Q: What is the CAS Number of Nicardipine Carboxylic acid Derivative Q: What is the storage condition of Nicardipine Carboxylic acid Derivative Q: What are the applications of Nicardipine Carboxylic acid Derivative
  • Lercanidipin Impurity 10
  • 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridin-3,5-dicarboxylic acid monomethyl ester
  • Methyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylicaci
  • 2,6-Dimethyl-5-methoxy carbonyl-4-(3-nitrophenylo)-1,4-dihydropyridine-3-carboxylic acid
  • Monomethyl 1, 4-dihydro-2, 6-dimethyl-4 -(3-nitrophenyl) pyridine-3, 5-dicarboxylic acid
  • Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, ≥ 98.0%
  • (+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid
  • Nicardipine EP Impurity 4
  • Beninidipine hydrochloride impurity E
  • UNII:5DU0E310OI
  • 74936-72-4
  • Heterocycle-Pyridine series
  • Pharmaceuticals
  • Intermediates & Fine Chemicals