Palonosetron

Product Name: Palonosetron
CAS No.: 149653-99-6
Chemical Name: Palonosetron
Synonyms: CID 148211;Palonosetron USP/EP/BP;(R)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de] isoquinolin-1-one;[r-(r*,r*)]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one;1H-Benz[de]isoquinolin-1-one, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-
CBNumber: CB62131052
Molecular Formula: C19H24N2O
Formula Weight: 296.41
MOL File: 149653-99-6.mol

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Palonosetron Property

Boiling point:: 470.4±45.0 °C(Predicted)
Density: 1.24
pka: 9.77±0.33(Predicted)

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Hazard and Precautionary Statements (GHS)

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Palonosetron Chemical Properties,Usage,Production

Indications

Palonosetron is approved by the US FDA for acute and delayed CINV and PONV.

Biological Activity

Palonosetron is a highly selective, high-affinity 5-HT3 receptor antagonist. Due to its structural difference from the first-generation 5-HT3 receptor antagonists, palonosetron has an affinity for the 5-HT3 receptor at least 30 times that of other similar drugs.

in vitro

Palonosetron is neither an inhibitor of CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2D6, CYP2E1 and CYP3A4/5 (CYP2C19 not studied) nor does it induce the activity of CYP1A2, CYP2D6 or CYP3A4/5.

Palonosetron Preparation Products And Raw materials

Raw materials

Preparation Products

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Palonosetron Suppliers

China 36 India 1 United States 1 Global 38

Chembest Research Laboratories Limited

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Beijing Comparison Pharmaceutical Technology Co., Ltd

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Nanjing Sunlida Biological Technology Co., Ltd.

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Shanghai Kewel Chemical Co., Ltd.

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Hubei widely chemical technology Co., Ltd.

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Jinan Yaoyan Pharmaceutical Co., Ltd.

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Hubei Changrun Biomedical Technology Co., Ltd.

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TOSUN PHARM

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Nanjing Meihao Pharmaceutical Technology Co., Ltd.

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View Lastest Price from Palonosetron manufacturers

Dideu Industries Group Limited

Product: Palonosetron 149653-99-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-09

149653-99-6, PalonosetronRelated Search:

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[r-(r*,r*)]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one

CID 148211

1H-Benz[de]isoquinolin-1-one, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-

Palonosetron USP/EP/BP

(R)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de] isoquinolin-1-one

149653-99-6