Palonosetron

Product Name: Palonosetron
CAS No.: 149653-99-6
Chemical Name: Palonosetron
Synonyms: CID 148211;Palonosetron USP/EP/BP;(R)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de] isoquinolin-1-one;[r-(r*,r*)]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one;1H-Benz[de]isoquinolin-1-one, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-
CBNumber: CB62131052
Molecular Formula: C19H24N2O
Formula Weight: 296.41
MOL File: 149653-99-6.mol

More

Less

Palonosetron Property

Boiling point:: 470.4±45.0 °C(Predicted)
Density: 1.24
pka: 9.77±0.33(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

Palonosetron Chemical Properties,Usage,Production

Indications

Palonosetron is approved by the US FDA for acute and delayed CINV and PONV.

Biological Activity

Palonosetron is a highly selective, high-affinity 5-HT3 receptor antagonist. Due to its structural difference from the first-generation 5-HT3 receptor antagonists, palonosetron has an affinity for the 5-HT3 receptor at least 30 times that of other similar drugs.

in vitro

Palonosetron is neither an inhibitor of CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2D6, CYP2E1 and CYP3A4/5 (CYP2C19 not studied) nor does it induce the activity of CYP1A2, CYP2D6 or CYP3A4/5.

Palonosetron Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Palonosetron Suppliers

China 36 India 1 United States 1 Global 38

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-52878169 15701683040
Email: sales@bjcomparison.com
Country: China
ProdList: 4689
Advantage: 58

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9911
Advantage: 50

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2984
Advantage: 58

Hubei widely chemical technology Co., Ltd.

Tel: 027-83991130 18627774460
Fax: 027-83991130
Email: 1718093273@QQ.COM
Country: China
ProdList: 1891
Advantage: 58

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Hubei Changrun Biomedical Technology Co., Ltd.

Tel: 027-63496417; 13667180236
Fax: 13476107660
Email: 3294393103@qq.com
Country: China
ProdList: 310
Advantage: 58

Changzhou Yongfeng Biomedicine Co. Ltd.

Tel: 15006117673
Fax: 2973592490@.com
Email: 2973592490@qq.com
Country: China
ProdList: 311
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 2881290884@qq.com
Country: China
ProdList: 7494
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19105
Advantage: 58

More

Less

View Lastest Price from Palonosetron manufacturers

Dideu Industries Group Limited

Product: Palonosetron 149653-99-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-09

149653-99-6, PalonosetronRelated Search:

2,2,4-Trimethylpentane Dolasetron mesylate N-OCTANE Granisetron hydrochloride Granisetron Palonosetron Hydrochloride RS 42358-197 PALONOSETRON HCL 6-Hydroxy Palonosetron Palonosetron impurity (S,R)-Palonosetron Hydrochloride (R,S)-Palonosetron Hydrochloride Palonosetron Impurity 11 Palonosetron Impurity 7 Palonosetron Impurity 12 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- (6S)-Hydroxy (S,S)-Palonosetron 1H-Benz[de]isoquinolin-1-one,2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-,(3aS)-

[r-(r*,r*)]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one

CID 148211

1H-Benz[de]isoquinolin-1-one, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-

Palonosetron USP/EP/BP

(R)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de] isoquinolin-1-one

149653-99-6