1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE

Product Name: 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE
CAS No.: 99010-24-9
Chemical Name: 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE
Synonyms: DesaMino IMiquiMod;Imiquimod USP RC A;Imiquimod Impurity-A;IMiquiMod Related CoMpound A;Imiquimod USP Related Compound A;Imiquimod USP related Substance A;1-Isobutyl-1H-imidazo[4,5-c]quinoli;1-ISOBUTYL-1H-IMIDAZO[4,5-C]QUINOLINE;1-(2-methylpropyl)imidazo[4,5-c]quinoline;1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE
CBNumber: CB6213635
Molecular Formula: C14H15N3
Formula Weight: 225.29
MOL File: 99010-24-9.mol

More

Less

1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE Property

Melting point:: 92-95℃
Boiling point:: 402.6±37.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 5.34±0.30(Predicted)
Appearance: Off-white to gray Solid
Major Application: pharmaceutical (small molecule)
InChI: 1S/C14H15N3/c1-10(2)8-17-9-16-13-7-15-12-6-4-3-5-11(12)14(13)17/h3-7,9-10H,8H2,1-2H3
InChIKey: CXYOCSTZCULCAE-UHFFFAOYSA-N
SMILES: [n]1(c2c(nc1)cnc3c2cccc3)CC(C)C
CAS DataBase Reference: 99010-24-9(CAS DataBase Reference)

More

Less

Safety

WGK Germany: WGK 3
HS Code: 2934990002
Storage Class: 11 - Combustible Solids

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1338324
Product name: Imiquimod Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25MG
Price: $1390
Updated: 2026/04/30

Matrix Scientific

Product number: 132442
Product name: 1-Isobutyl-1H-imidazo[4,5-c]quinoline
Packaging: 50.00g
Price: $73
Updated: 2026/05/18

Matrix Scientific

Product number: 132442
Product name: 1-Isobutyl-1H-imidazo[4,5-c]quinoline
Packaging: 100.00g
Price: $91
Updated: 2026/05/18

Matrix Scientific

Product number: 132442
Product name: 1-Isobutyl-1H-imidazo[4,5-c]quinoline
Packaging: 250.00g
Price: $112
Updated: 2026/05/18

Synthonix

Product number: B57667
Product name: 1-Isobutyl-1H-imidazo[4,5-c]quinoline
Purity: 95%
Packaging: 100mg
Price: $170
Updated: 2026/05/06

More

Less

1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE Chemical Properties,Usage,Production

Uses

Desamino Imiquimod is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.

Synthesis

99010-09-0

64-18-6

99010-24-9

Example 1 Preparation of 1-isobutyl-1H-imidazo[4,5-c]quinoline (II): 3-amino-4-isobutylaminoquinoline (215 g, 1.0 mol) was dissolved in formic acid (1000 ml), and the reaction mixture was heated to reflux at 110-115°C. The reflux reaction was maintained for 8-10 hours. Upon completion of the reaction, the excess formic acid was removed by distillation under reduced pressure and the residue was diluted with 3.5 liters of water. Subsequently, the pH was adjusted to 10-11 with 30% sodium hydroxide solution at 20 °C. The reaction mixture was cooled to 100 °C and stirring was continued for 3 h. The solid product was precipitated. The solid was collected by filtration, washed with water and dried to give 1-isobutyl-1H-imidazo[4,5-c]quinoline (221 g, 98% yield) as a white solid. Melting point: 91-94°C. Mass spectrum (m/z): M+ 226. 1H NMR (200 MHz, DMSO-d6): δ-value see attached.

References

[1] Patent: WO2006/70379, 2006, A1. Location in patent: Page/Page column 8
[2] Patent: WO2006/70408, 2006, A2. Location in patent: Page/Page column 7; 11
[3] Patent: US6348462, 2002, B1. Location in patent: Page column 22
[4] Patent: WO2014/120995, 2014, A2. Location in patent: Page/Page column 174-175

1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE Suppliers

China 70 India 4 Ukraine 1 United Kingdom 2 United States 12 Global 89

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Adamas Reagent, Ltd.

Tel: 400-6009262 15618770481
Fax: 021-64823266
Email: yhx@titansci.com
Country: China
ProdList: 14100
Advantage: 59

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Nantong MYBio-pharm. Co., Ltd.

Tel: 0513-85921823 18662920231
Fax: 86-513-85012876
Email: sales@ntminyanmedical.com
Country: China
ProdList: 4369
Advantage: 58

Shanghai Xiang Xin Industrial Co., Ltd.

Tel: 021-50211651 13651607026
Fax: +86-21-50211651
Email: sales@xxgmpharm.com
Country: China
ProdList: 495
Advantage: 58

ShangHai Angti Biotechnology Co., Ltd.

Tel: 13764913901
Fax: -
Email: info@angtibio.com
Country: China
ProdList: 4975
Advantage: 55

Shanghai Qiao Chemical Science Co., Ltd

Tel: 021-58892003 18601689453;
Email: info@qiaochem.com
Country: China
ProdList: 6075
Advantage: 65

Shanghai Qing Cang Chemical Technology Co., Ltd.

Tel: 00000000000
Fax: -
Email: sales@qingcangchem.com
Country: China
ProdList: 509
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 17801761073
Email: 3193328036@qq.com
Country: China
ProdList: 6338
Advantage: 68

More

Less

View Lastest Price from 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE manufacturers

Career Henan Chemical Co

Product: 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE 99010-24-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kgs
Release date: 2020-03-05

99010-24-9, 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINERelated Search:

Imiquimod Impurity 2 4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol [99010-09-0], C13H17N3,215.30 Imiquimod Impurity 6 N4-(2-METHYLPROPYL)-3,4-QUINOLINEDIAMINE Imiquimod Related Compound B (25 mg) (1-Isobutyl-1H-imidazo[4,5-c]quinoline 5-oxide) Imiquimod Related Compound D (25 mg) (1-Propyl-1H-imidazo[4,5-c]quinolin-4-amine) Imiquimod Impurity 5 4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE Imiquimod IMIQUIMOD ACETATE RESIQUIMOD IMIQUIMOD, [3H]- 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE 4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE 98%MIN

1H-IMIDAZO[4,5-C]QUINOLINE, 1-(2-METHYLPROPYL)-

1-ISOBUTYL-1H-IMIDAZO[4,5-C]QUINOLINE

1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE

Imiquimod Related Compound A (25 mg) (1-Isobutyl-1H-imidazo[4,5-c]quinoline)

IMiquiMod Related CoMpound A

DesaMino IMiquiMod

1-(2-methylpropyl)imidazo[4,5-c]quinoline

1-Isobutyl-1H-imidazo[4,5-c]quinoli

Imiquimod USP RC A

Imiquimod Impurity 1 (Imiquimod Related Compound A)

Imiquimod Impurity-A

Imiquimod Related Compound A (1-Isobutyl-1H-imidazo[4,5-c]quinoline) (1338324)

Imiquimod USP Related Compound A

Imiquimod USP related Substance A

1-Isobutyl-1H-imidazo[4,5-c]quinoline (Desaminoimiquimod)

99010-24-9