4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
- Product Name
- 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
- CAS No.
- 99010-64-7
- Chemical Name
- 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
- Synonyms
- cas 99010-64-7;Imiquimod USP RC C;Imiquimod Impurity-C;DesaMino ChloroiMiquiMod;1H-Imidazo[4,5-c]quinoline,;IMiquiMod Related CoMpound C;Imiquimod USP Related Compound C;4-Chloro-1-isobutyl-1H-imidazo[4,5-;1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(;4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE
- CBNumber
- CB6449735
- Molecular Formula
- C14H14ClN3
- Formula Weight
- 259.73
- MOL File
- 99010-64-7.mol
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Property
- Melting point:
- 139-140 °C(Solv: isopropanol (67-63-0))
- Boiling point:
- 427.5±48.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform (Sparingly), Methanol (Slightly)
- form
- Solid
- pka
- 3.15±0.30(Predicted)
- color
- White to Off-White
- CAS DataBase Reference
- 99010-64-7(CAS DataBase Reference)
Safety
- HS Code
- 2934990002
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1338346
- Product name
- Imiquimod Related Compound C
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 25MG
- Price
- $1230
- Updated
- 2022/05/15
- Product number
- 446210
- Product name
- Desamino Chloroimiquimod
- Packaging
- 5mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- D288295
- Product name
- DesaminoChloroimiquimod
- Packaging
- 5mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- S437
- Product name
- 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
- Packaging
- 10g
- Price
- $49
- Updated
- 2021/12/16
- Product number
- S437
- Product name
- 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
- Packaging
- 25g
- Price
- $100
- Updated
- 2021/12/16
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Chemical Properties,Usage,Production
Description
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is a chemical product that has been used as a photosynthetic activator in weed science and pest control. It has been shown to significantly increase the growth rate of wheat, soybean, and oilseed crops. It is also effective at controlling weeds by inhibiting their ability to produce chlorophyll, thereby preventing them from photosynthesizing. 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline has also been shown to be an effective herbicide for agricultural use.
Uses
Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.
Synthesis
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is prepared by the reaction of 2-chloro-N4-(2-methylpropyl)quinoline-3,4-diamine and orthoformic acid triethyl ester. The specific synthesis steps are as follows:
A suspension of 2-chloro-N4 -(2-methylpropyl)-3,4-quinolinediamine (35 g) and triethylorthoformate (52.3 g, 2.5 eq) was heated at 145° C. for 10 h, during which time ethanol was removed by distillation. The resulting mixture was cooled to room temperature and the solid was removed by filtration. The solid was dissolved in hydrochloric acid (100 mL, 4N). The resulting solution was added to a solution of sodium hydroxide. The precipitate was filtered and washed with water to afford the product 4-chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline in 92% yield.
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline manufacturers
- Product
- 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline 99010-64-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 90%-99.99%
- Supply Ability
- 1000kgs
- Release date
- 2019-07-02