ChemicalBook > CAS DataBase List > 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

Product Name
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
CAS No.
99010-64-7
Chemical Name
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
Synonyms
cas 99010-64-7;Imiquimod USP RC C;Imiquimod Impurity-C;DesaMino ChloroiMiquiMod;1H-Imidazo[4,5-c]quinoline,;IMiquiMod Related CoMpound C;Imiquimod USP Related Compound C;4-Chloro-1-isobutyl-1H-imidazo[4,5-;1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(;4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE
CBNumber
CB6449735
Molecular Formula
C14H14ClN3
Formula Weight
259.73
MOL File
99010-64-7.mol
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4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Property

Melting point:
139-140 °C(Solv: isopropanol (67-63-0))
Boiling point:
427.5±48.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Solid
pka
3.15±0.30(Predicted)
color 
White to Off-White
CAS DataBase Reference
99010-64-7(CAS DataBase Reference)
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Safety

HS Code 
2934990002
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1338346
Product name
Imiquimod Related Compound C
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25MG
Price
$1230
Updated
2022/05/15
Usbiological
Product number
446210
Product name
Desamino Chloroimiquimod
Packaging
5mg
Price
$460
Updated
2021/12/16
TRC
Product number
D288295
Product name
DesaminoChloroimiquimod
Packaging
5mg
Price
$185
Updated
2021/12/16
AK Scientific
Product number
S437
Product name
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
Packaging
10g
Price
$49
Updated
2021/12/16
AK Scientific
Product number
S437
Product name
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
Packaging
25g
Price
$100
Updated
2021/12/16
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4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Chemical Properties,Usage,Production

Description

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is a chemical product that has been used as a photosynthetic activator in weed science and pest control. It has been shown to significantly increase the growth rate of wheat, soybean, and oilseed crops. It is also effective at controlling weeds by inhibiting their ability to produce chlorophyll, thereby preventing them from photosynthesizing. 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline has also been shown to be an effective herbicide for agricultural use.

Uses

Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.

Synthesis

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is prepared by the reaction of 2-chloro-N4-(2-methylpropyl)quinoline-3,4-diamine and orthoformic acid triethyl ester. The specific synthesis steps are as follows:
A suspension of 2-chloro-N4 -(2-methylpropyl)-3,4-quinolinediamine (35 g) and triethylorthoformate (52.3 g, 2.5 eq) was heated at 145° C. for 10 h, during which time ethanol was removed by distillation. The resulting mixture was cooled to room temperature and the solid was removed by filtration. The solid was dissolved in hydrochloric acid (100 mL, 4N). The resulting solution was added to a solution of sodium hydroxide. The precipitate was filtered and washed with water to afford the product 4-chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline in 92% yield.

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline manufacturers

Career Henan Chemical Co
Product
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline 99010-64-7
Price
US $1.00/KG
Min. Order
1KG
Purity
90%-99.99%
Supply Ability
1000kgs
Release date
2019-07-02

99010-64-7, 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolineRelated Search:

4-amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol [99010-09-0], C13H17N3,215.30 Imiquimod Related Compound B (25 mg) (1-Isobutyl-1H-imidazo[4,5-c]quinoline 5-oxide) Imiquimod Related Compound D (25 mg) (1-Propyl-1H-imidazo[4,5-c]quinolin-4-amine) Imiquimod Chloromethyl isopropyl carbonate Epichlorohydrin 1-Methylimidazole 3-Methyl-2-butanone Imiquimod Impurity 2 Imiquimod Impurity 6 Imiquimod Impurity 5 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE Difluorochloromethane Chloroacetic acid RESIQUIMOD 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline 4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE 98%MIN

  • 4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE
  • 1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(
  • 4-chloro-1-(2-methylpropyl)imidazo[4,5-c]quinoline
  • 4-CHLORO-1-ISOBUTYL-1H-IMIDAZOBEN[4,5-C]QUINOLINE
  • 1-[2-METHYLPROPYL]-1H-2-CHLOROIMIDAZO-[4,5-C]QUINOLINE
  • 1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(2-METHYLPROPYL)
  • 4-Chloro-1-(2-methylpropyl)-1H-imidazo-(4,5c)quinolinone
  • 2-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINONE
  • 1H-Imidazo[4,5-c]quinoline,
  • 4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE
  • 1H-Imidazo[4,5-c]quinoline, -chloro-1-(2-methylpropyl)-
  • 1H-Imidazo[4,5-c]quinolinone,2-chloro-1-(2-methylpropyl)
  • Imiquimod Related Compound C (25 mg) (4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline)
  • 1-H-IMIDAZO[4,5-C]QUINOLINONE,4-CHLORO-1-(2-METHYL PROPYL)
  • IMiquiMod Related CoMpound C
  • DesaMino ChloroiMiquiMod
  • 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline###4-Chloro-1-(2-methylpropyl)-1H-imidazole[4,5-c]quinoline
  • Imiquimod USP Related Compound C
  • 4-Chloro-1-isobutyl-1H-imidazo[4,5-
  • Imiquimod USP RC C
  • Imiquimod Impurity 3 (Imiquimod Related Compound C)
  • Imiquimod Impurity-C
  • Imiquimod Related Compound C (4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline) (1338346)
  • 4-CHLORO-1-ISOBUTYL-1H-IMIDAZO (4,5'D)QUINOLINE
  • cas 99010-64-7
  • 4-CHLORO-1-ISOBUTYL-1H-IMIDAZO (4,5'D)QUINOLINE
  • 99010-64-7
  • C14H14ClN3
  • Quinolines, Quinazolines and derivatives
  • Intermediates of Imiquimod
  • API intermediates