ChemicalBook > CAS DataBase List > N,N'-Bis(phenylmethyl)-1,2-ethanediamine

N,N'-Bis(phenylmethyl)-1,2-ethanediamine

Product Name
N,N'-Bis(phenylmethyl)-1,2-ethanediamine
CAS No.
140-28-3
Chemical Name
N,N'-Bis(phenylmethyl)-1,2-ethanediamine
Synonyms
Dbed;BENZATHINE;N1,N2-Dibenzylethane-1,2-diaMine;Benzatin;Nsc5632;usafdo-53;USAF do-53;N,N'-DibenzyL;BENZATHINE 99%;enediamine Diacetate SaL
CBNumber
CB6214137
Molecular Formula
C16H20N2
Formula Weight
240.34
MOL File
140-28-3.mol
More
Less

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Property

Melting point:
23-25°C
Boiling point:
195 °C4 mm Hg(lit.)
Density 
1.02 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.565(lit.)
Flash point:
>230 °F
storage temp. 
Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Water (Slightly)
form 
Solid
pka
9.15±0.19(Predicted)
Specific Gravity
1.025
color 
White to Off-White
Water Solubility 
Slightly soluble in water.
FreezingPoint 
21.0 to 25.0 ℃
Sensitive 
Air Sensitive
Merck 
14,1064
BRN 
786668
CAS DataBase Reference
140-28-3(CAS DataBase Reference)
NIST Chemistry Reference
1,2-Ethanediamine, N,N'-bis(phenylmethyl)-(140-28-3)
EPA Substance Registry System
1,2-Ethanediamine, N,N'-bis(phenylmethyl)- (140-28-3)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
RIDADR 
2927
WGK Germany 
3
RTECS 
KV3325000
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29215990
Toxicity
LD50 orl-mus: 388 mg/kg CNCRA6 52,579,68
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D35201
Product name
N,N′-Dibenzylethylenediamine
Purity
97%
Packaging
25g
Price
$94.9
Updated
2024/03/01
Sigma-Aldrich
Product number
D35201
Product name
N,N′-Dibenzylethylenediamine
Purity
97%
Packaging
100g
Price
$217
Updated
2024/03/01
TCI Chemical
Product number
D1807
Product name
N,N'-Dibenzylethylenediamine
Purity
>98.0%(GC)(T)
Packaging
25mL
Price
$94
Updated
2024/03/01
TCI Chemical
Product number
D1807
Product name
N,N'-Dibenzylethylenediamine
Purity
>98.0%(GC)(T)
Packaging
500mL
Price
$906
Updated
2024/03/01
Alfa Aesar
Product number
L03540
Product name
N,N'-Dibenzylethylenediamine, 97%
Packaging
25g
Price
$73.65
Updated
2024/03/01
More
Less

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Chemical Properties,Usage,Production

Chemical Properties

light yellow liquid

Uses

N,N'-Dibenzylethylenediamine is an intermediate of cephalosporin and penicillin.

Definition

ChEBI: Benzathine is a diamine. It is a conjugate base of a benzathine(1+).

Synthesis Reference(s)

The Journal of Organic Chemistry, 55, p. 3209, 1990 DOI: 10.1021/jo00297a042

Safety Profile

Poison by ingestion,intraperitoneal, and parenteral routes. When heated todecomposition it emits toxic vapors of NOx.

Purification Methods

Dissolve DBED in acid, extract with toluene, basify, extract it with Et2O, dry over solid KOH, evaporate and fractionate it in vacuo. The diacetate crystallises from H2O by addition of EtOH and has m 111o (solubility in H2O is ~25%). The dihydrochloride has m 306-308o (from H2O) and the dipicrate has m 212o(dec) (from H2O). [Frost et al., J Am Chem Soc 71 3842 1949, Beilstein 12 H 1067, 12 III 2304.]

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N,N'-Bis(phenylmethyl)-1,2-ethanediamine Suppliers

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1686
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44700
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9493
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8033
Advantage
55
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4528
Advantage
56
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Hangzhou Trylead Chemical Technology Co.,LTD
Tel
0571-87086220 18657191323
Fax
0571-87012927
Email
zyf@trylead-chem.com
Country
China
ProdList
306
Advantage
64
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17993
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9625
Advantage
58
Shanghai Xingui Biotechnology Co., Ltd.
Tel
17501653715
Email
xingui2022@126.com
Country
China
ProdList
10033
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15885
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10063
Advantage
53
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6490
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12357
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Weifang QianJin Fine Chemical Co., Ltd.
Tel
0536-2457064 13031698386
Fax
0536-8897109
Email
1577399715@qq.COM
Country
China
ProdList
1695
Advantage
55
Giant chemicals
Tel
028-85434334 18108076537
Fax
QQ:245797092
Email
market@gianthx.com
Country
China
ProdList
4512
Advantage
56
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12041
Advantage
58
Chengdu Research Accelerators Technology Co., Ltd.
Tel
028-64353063
Fax
028-64353063 QQ:784253935
Email
reacchemical@163.com
Country
China
ProdList
5259
Advantage
58
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9030
Advantage
60
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862,442785678,326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9638
Advantage
58
AgileBioChem Co., Ltd.
Tel
18055517827
Email
sales@agilebiochem.com
Country
China
ProdList
1002
Advantage
50
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
9859
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131980
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13336
Advantage
58
Chengdu Synguider Technology Co., Ltd.
Tel
400-086-3412 028-85062459
Fax
028-85062459
Email
synguider@163.com
Country
China
ProdList
3300
Advantage
55
Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9190
Advantage
65
Shanghai Orgchem Co.,Ltd.
Tel
+86-21-5877 1921
Fax
+86-21-5877 1925
Email
info@chemofchina.com
Country
China
ProdList
9661
Advantage
55
JinJin Le Chemical Co., Ltd
Tel
10106090
Email
jjlchem2@163.com
Country
China
ProdList
9986
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19806
Advantage
60
LinkChem Co.,Ltd.
Tel
021-021-58950110 13124863828
Fax
021-20922272
Email
sales@linkchem.cn
Country
China
ProdList
2999
Advantage
58
Jiaxing Deyi Chemical Co., Ltd.
Tel
0573-86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
7960
Advantage
58
More
Less

View Lastest Price from N,N'-Bis(phenylmethyl)-1,2-ethanediamine manufacturers

Hebei Duling International Trade Co. LTD
Product
N,N'-Bis(phenylmethyl)-1,2-ethanediamine 140-28-3
Price
US $56.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 tons
Release date
2023-04-24
Career Henan Chemical Co
Product
N,N'-Bis(phenylmethyl)-1,2-ethanediamine 140-28-3
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg , 5kg, 50kg
Release date
2020-01-17

140-28-3, N,N'-Bis(phenylmethyl)-1,2-ethanediamineRelated Search:


  • N,N'-DIBENZYLETHYLENEDIAMINE
  • N'N-DIBENZYL-ETHYLENEDIAMINE
  • 1,2-di(benzylamino)ethane
  • Benzathine~1,2-Bis(benzylamino)ethane
  • N,N`-dibenzylethylendiamine
  • BENZATHINE 99%
  • 1 2-BIS(BENZYLAMINO)ETHANE 99%
  • 1,2-ETHANEDIAMINE,N,N''-BIS(PHENYLMETHYL)-
  • N,N'-Bis(phenylmethyl)ethane-1,2-diamine
  • Nsc5632
  • N1,N2-Dibenzylethane-1,2-diaMine
  • N,N'-DibenzylethylenediaMine Diacetate Salt
  • <i>N</i>,<i>N</i>'-Dibenzylethylenediamine
  • Benzatin
  • Dbed
  • n,n’-bis(phenylmethyl)-2-ethanediamine
  • n,n’-dibenzyl-ethylenediamin
  • N,N'-Dibenzyl-1,2-ethanediamine
  • N,N'-Dibenzyl-1,2-ethylenediamine
  • N,N'-Dibenzyl-ethane-1,2-diamine
  • USAF do-53
  • usafdo-53
  • 1 2-BIS(BENZYLAMINO)ETHANE
  • ETHYLENEDIAMINE-N N'-DIBENZYL
  • BENZATHINE
  • N,N'-BIS(PHENYLMETHYL)-1,2-ETHANEDIAMINE
  • DBE, N,N'-Dibenzylethylenediamine
  • N,N'-Dibenzylethylenediamine&gt
  • enediamine Diacetate SaL
  • N,N'-DibenzyL
  • ETHYLENEDIAMINE-N,N'-DIBENZYL 140-28-3
  • N,N'-Bis(phenylmethyl)-1,2-ethanediamine ISO 9001:2015 REACH
  • Enzastaurin Impurity 2 (Bisindolylmaleimide IV)
  • N,N'-Dibenzylethylenediamine
  • N,N'-Bis(phenylmethyl)-1,2-ethanediamine
  • 140-28-3
  • C6H5CH2NHCH2CH2NHCH2C6H5
  • C6H5CH2NHCH2CH2NHCH2C6H52CH3CO2H
  • Organic Building Blocks
  • Nitrogen Compounds
  • Polyamines
  • Building Blocks
  • Nitrogen Compounds
  • Organic Building Blocks
  • Polyamines