DAGO ACETATE SALT

Product Name: DAGO ACETATE SALT
CAS No.: 100929-53-1
Chemical Name: DAGO ACETATE SALT
Synonyms: DAMGO, DAGO;DAMGO acetate;DAGO ACETATE SALT;DAMGO ACETATE SALT;ala(2)-mephe(4)-gly(5)-enkephali;Enkephalin, Ala(2)-MePhe(4)-Gly(5)-;(D-ala2,N-me-phe4,gly5-ol)-enkephalin*acetate;TYR-D-ALA-GLY-N-METHYL-PHE-GLY-OL ACETATE SALT;DAGO, DAMGO, Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol;[D-ALA2,N-ME-PHE4,GLY5-OL]-ENKEPHALIN ACETATE SALT
CBNumber: CB6215598
Molecular Formula: C28H39N5O8
Formula Weight: 573.64
MOL File: 100929-53-1.mol

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DAGO ACETATE SALT Property

storage temp.: −20°C
form: Powder
EPA Substance Registry System: L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-N-.alpha.-methyl-L-phenylalaninamide monoacetate (salt) (100929-53-1)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E7384
Product name: [D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt
Purity: ≥97% (HPLC)
Packaging: 1mg
Price: $62.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: E7384
Product name: [D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $204
Updated: 2024/03/01

Alfa Aesar

Product number: J60431
Product name: DAGO
Packaging: 5mg
Price: $122
Updated: 2021/12/16

Sigma-Aldrich

Product number: E7384
Product name: [D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt
Purity: ≥97% (HPLC)
Packaging: 10mg
Price: $349
Updated: 2024/03/01

Sigma-Aldrich

Product number: E7384
Product name: [D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt
Purity: ≥97% (HPLC)
Packaging: 50mg
Price: $1400
Updated: 2024/03/01

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DAGO ACETATE SALT Chemical Properties,Usage,Production

Uses

Mu-opioid receptor-specific enkephalin analog

Uses

[D-Ala², N-Me-Phe⁴, Gly⁵-ol]-Enkephalin acetate salt or DAMGO has been used:

for use as a positive control in the assay of G-protein activation with μ-opioid receptor, to assay the inhibition of cAMP inhibition by DAMGO
for the determination of the suppression of contraction by opioid receptors
to determine whether the peripheral application of DAMGO suppresses the hypertonic saline (HS)-induced masseter nociception in slightly anaesthetized rats

General Description

[D-Ala², N-Me-Phe⁴, Gly⁵-ol]-Enkephalin acetate salt or DAMGO is a full agonist of the μ-opioid receptor. μ-opioid receptor is encoded by the OPRM1 gene, which has a predominant expression in reward-processing areas of brain. It acts as a receptor for endogenous opioids such as β-endorphin, encephalin, as well as foreign opioids such as morphine, heroin, and methadone.

Biochem/physiol Actions

Enkephalin analog that is a selective agonist at μ-opioid receptors.

DAGO ACETATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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DAGO ACETATE SALT Suppliers

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100929-53-1, DAGO ACETATE SALTRelated Search:

DAGO (3,5-DIIODO-TYR1)-DAGO ACETATE SALT DAGO ACETATE SALT N-METHYL-N-(2-PHENYLETHYL)ETHANE-1,2-DIAMINE

ala(2)-mephe(4)-gly(5)-enkephali

DAMGO ACETATE SALT

DAGO ACETATE SALT

[D-ALA2,N-ME-PHE4,GLY5-OL]-ENKEPHALIN ACETATE SALT

Enkephalin, Ala(2)-MePhe(4)-Gly(5)-

(D-alanine2,N-methylphenylalanine4,glycine3-ol)enkephalin

DAGO, DAMGO, Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol

L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-nalpha-methyl-, monoacetate (salt)

L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-N-alpha-methyl-L-phenylalaninamide monoacetate (salt)

TYR-D-ALA-GLY-N-METHYL-PHE-GLY-OL ACETATE SALT

(D-ala2,N-me-phe4,gly5-ol)-enkephalin*acetate

L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-nalpha-methyl-L-phenylalaninamide monoacetate (salt)

DAMGO, DAGO

DAMGO acetate

(D-Ala?,N-Me-Phe?,glycinol?)-Enkephalin acetate salt

(2S)-2-amino-N-[(1R)-1-[[[(1S)-1-(2-hydroxyethylcarbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl]methylcarbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide

100929-53-1

C28H39N5O8

C26H35N5O6C2H4O2

Biochemicals and Reagents

Amino Acids and Peptides

BioChemical

Peptides

Opioid Peptides

Enkephalins