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PECTIC ACID

Product Name
PECTIC ACID
CAS No.
9046-40-6
Chemical Name
PECTIC ACID
Synonyms
PECTIC ACID;PECTIC ACID tech;Pectic Acid pure;Methyl protopectin;PECTIC ACID FROM APPLES;Pectic acid, ≥85% esterified;pectin, esterified from citrus fruit;PECTIN, ESTERIFIED, DEGREE OF*ESTERI;Pectic acid from apple, Poly-D-galacturonic acid;Galacturonate polysaccharides HM from citrus (sodium salt)
CBNumber
CB6219864
Molecular Formula
C18H26O19
Formula Weight
546.38764
MOL File
9046-40-6.mol
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PECTIC ACID Property

form 
powder
biological source
synthetic
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
YP33892
Product name
Pectic acid
Packaging
25g
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
YP33892
Product name
Pectic acid
Packaging
50g
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
YP33892
Product name
Pectic acid
Packaging
100g
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
YP33892
Product name
Pectic acid
Packaging
250g
Price
$400
Updated
2021/12/16
Biosynth Carbosynth
Product number
YP33892
Product name
Pectic acid
Packaging
500g
Price
$500
Updated
2021/12/16
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PECTIC ACID Chemical Properties,Usage,Production

Chemical Properties

powder pH (1%) 4.2-5

Uses

forms strong resilient films and fibers

Uses

Those pectic substances that are essentially void of methoxyl groups and have carboxyl groups only. They have varying degrees of neutralization. The divalent salts are slightly soluble in water and must be converted to the sodium or potassium forms for dissolution. It gels in the presence of calcium or other divalent cations.

in vivo

Pectic acid (25 and 100 mg/kg, oral gavage) increases colon length, downregulates disease activity index, histopathological score and proinflammatory cytokine levels in Ulcerative colitis (UC) mice[3].
Pectic acid (6.25 and 12.5 mg/kg, intravenous injection) rescues the reduction in colon length in UC mice[3].

Animal Model:Ulcerative colitis (UC) mice[3]
Dosage:25, 100 mg/kg
Administration:Oral gavage
Result:Exhibited the longest colon, lowest DAI, and minimum histopathological score.
Decreased the proinflammatory cytokines in the colonic tissue of UC mice.
Animal Model:Ulcerative colitis (UC) mice[3]
Dosage:6.25, 12.5 mg/kg
Administration:Intravenous injection
Result:Decreased the spleen and thymus index.
Restored the Th17/Treg balance in the spleen and lamina propria of UC mice.
Improved the gut microbiota composition.

IC 50

Human Endogenous Metabolite

Purification Methods

Citrus pectic acid (500g) is refluxed for 18hours with 1.5L of 70% EtOH, and the suspension is filtered hot. The residue is washed with hot 70% EtOH and finally with ether. It is dried in a current of air, ground and dried for 18hours at 80o under vacuum. [Morell & Link J Biol Chem 100 385 1933.] It can be further purified by dispersing it in water and adding just enough dilute NaOH to dissolve the pectic acid, then passing the solution through columns of cation-and anion-exchange resins [Williams & Johnson Ind Eng Chem (Anal Ed) 16 23 1944], and precipitating with two volumes of 95% EtOH containing 0.01% HCl. The precipitate is worked with 95% EtOH, then Et2O, dried and ground. [Rees & Walsh Angew Chem Int Edn 16 214 1977, Rees Adv Carbohydr Chem 24 267 1969.]

PECTIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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PECTIC ACID Suppliers

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Sigma-Aldrich
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View Lastest Price from PECTIC ACID manufacturers

Career Henan Chemical Co
Product
PECTIC ACID 9046-40-6
Price
US $1.00/KG
Min. Order
1g
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-10

9046-40-6, PECTIC ACIDRelated Search:


  • PECTIC ACID FROM APPLES
  • pectin, esterified from citrus fruit
  • PECTIC ACID tech
  • PECTIC ACID
  • Pectic acid, ≥85% esterified
  • Pectic acid from apple, Poly-D-galacturonic acid
  • PECTIN, ESTERIFIED, DEGREE OF*ESTERI
  • Methyl protopectin
  • Pectin, esterified from citrus fruit extent of labeling: >=85% esterified
  • Galacturonate polysaccharides HM from citrus (sodium salt)
  • Pectic Acid pure
  • 9046-40-6
  • Carbohydrates
  • Carbohydrates A to
  • Carbohydrates P-ZBiochemicals and Reagents
  • Polysaccharide