6-Bromohexanoic acid
Organic Intermediate- Product Name
- 6-Bromohexanoic acid
- CAS No.
- 4224-70-8
- Chemical Name
- 6-Bromohexanoic acid
- Synonyms
- Hexanoic acid, 6-bromo-;6-bromohexanoate;ISBO-007;AKOS BB/0098;6-BroMhexine acid;6-bromo-hexanoicaci;6-BroMhexanoic acid;6-BROMOCAPROIC ACID;RARECHEM AL BO 0317;6-bromohexonic acid
- CBNumber
- CB6221568
- Molecular Formula
- C6H11BrO2
- Formula Weight
- 195.05
- MOL File
- 4224-70-8.mol
6-Bromohexanoic acid Property
- Melting point:
- 32-34 °C (lit.)
- Boiling point:
- 165-170 °C/20 mmHg (lit.)
- Density
- 1.3996 (rough estimate)
- refractive index
- 1.4790 (estimate)
- Flash point:
- 154 °F
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- methanol: 0.1 g/mL, clear, colorless
- pka
- 4.72±0.10(Predicted)
- form
- Low Melting Crystals
- color
- White to light orange
- BRN
- 1749740
- InChIKey
- NVRVNSHHLPQGCU-UHFFFAOYSA-N
- LogP
- 1.700 (est)
- CAS DataBase Reference
- 4224-70-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Hexanoic acid, 6-bromo-(4224-70-8)
- EPA Substance Registry System
- Hexanoic acid, 6-bromo- (4224-70-8)
Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45-28A
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- F
- 8
- Hazard Note
- Corrosive/Harmful
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29159080
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
N-Bromosuccinimide Price
- Product number
- 150452
- Product name
- 6-Bromohexanoic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $36.4
- Updated
- 2024/03/01
- Product number
- 150452
- Product name
- 6-Bromohexanoic acid
- Purity
- 97%
- Packaging
- 25g
- Price
- $74
- Updated
- 2024/03/01
- Product number
- B1290
- Product name
- 6-Bromohexanoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $64
- Updated
- 2024/03/01
- Product number
- B1290
- Product name
- 6-Bromohexanoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 250g
- Price
- $361
- Updated
- 2024/03/01
- Product number
- A15761
- Product name
- 6-Bromohexanoic acid, 98+%
- Packaging
- 25g
- Price
- $65.65
- Updated
- 2024/03/01
6-Bromohexanoic acid Chemical Properties,Usage,Production
Organic Intermediate
6-bromohexanoic acid(CAS:4224-70-8), also called 6-bromohexanoic acid or 6-bromo-hexanoic acid, is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. 6-Bromohexanoic acid is used in the preparation of N-acylsulfonamides, diarylthioethers and 2-lithio-1,3-dithian. It is widely used as an intermediate in organic synthesis. Here, we introduced a method for making this compound.
Chemical Properties
White to light orange low melting crystals
Uses
Employed in a direct preparation of N-acylsulfonamides on treatment with tosyl isocyanate (189278)1 and alkyl ketones from alkyl iodides and metallic strontium.2
Uses
6-Bromohexanoic acid is used in the preparation of N-acylsulfonamides, diarylthioethers and 2-lithio-1,3-dithian. It is widely used as an intermediate in organic synthesis.
Uses
6-Bromohexanoic acid was used in the preparation of N-acylsulfonamides on treatment with tosyl isocyanate (189278) and alkyl ketones from alkyl iodides and metallic strontium. It was also used in the synthesis of anionic mitomycin C-dextran conjugate (MMC-D), 2-lithio-1,3-dithian and diaryl thioethers.
Definition
ChEBI: 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It is functionally related to a hexanoic acid.
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 5137, 1950 DOI: 10.1021/ja01167a091
Synthesis
The preparation method of the high purity 6-bromocaproic acid: the exsiccant bromize hydrogen gas is directly fed contain in the organic solvent of 6-caprolactone, exsiccant bromize hydrogen gas usage quantity is 6-caprolactone 1.0-2.0 doubly (mol ratio); Stir, ring-opening reaction takes place, temperature of reaction is 0 ℃ ~ 100 ℃, generates high purity 6-bromocaproic acid.
6-Bromohexanoic acid Preparation Products And Raw materials
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View Lastest Price from 6-Bromohexanoic acid manufacturers
- Product
- 6-Bromohexanoic acid 4224-70-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 10 tons
- Release date
- 2024-04-26
- Product
- 6-Bromohexanoic acid 4224-70-8
- Price
- US $8.00-0.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09
- Product
- 6-Bromohexanoic acid 4224-70-8
- Price
- US $20.00-2.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-09-15