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(2E)-3-(1H-Imidazole-4-yl)propenoic acid

Product Name
(2E)-3-(1H-Imidazole-4-yl)propenoic acid
CAS No.
3465-72-3
Chemical Name
(2E)-3-(1H-Imidazole-4-yl)propenoic acid
Synonyms
Chebi:30817;Trans-uric acid;(E)-Urocanic acid;trans-Urocanic acid;trans-UrocanicAcid>Thiamazole Impurity 5;trans-Urocanic Acid;(E)-3-(4-Imidazolyl)acrylic acid;(αE)-1H-Imidazole-4-acrylic acid;(E)-3-(5-Imidazolyl)acrylic Acid
CBNumber
CB62225096
Molecular Formula
C6H6N2O2
Formula Weight
138.12
MOL File
3465-72-3.mol
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(2E)-3-(1H-Imidazole-4-yl)propenoic acid Property

Melting point:
225 °C
Boiling point:
456.9±20.0 °C(Predicted)
Density 
1.430±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 3 mg/ml; DMSO: 15 mg/ml; PBS (pH 7.2): 0.3 mg/ml
form 
powder to crystal
pka
3.55±0.10(Predicted)
color 
White to Almost white
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Safety

HS Code 
2933.29.9000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
I0002
Product name
trans-Urocanic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$135
Updated
2025/07/31
Cayman Chemical
Product number
16228
Product name
trans-Urocanic Acid
Purity
≥98%
Packaging
1g
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
16228
Product name
trans-Urocanic Acid
Purity
≥98%
Packaging
5g
Price
$134
Updated
2024/03/01
TRC
Product number
I577448
Product name
(E)-3-(1H-Imidazol-5-yl)acrylicAcid
Packaging
5g
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
176213
Product name
(E)-3-(1H-Imidazol-4-yl)-2-propenoic acid
Packaging
5g
Price
$810
Updated
2021/12/16
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(2E)-3-(1H-Imidazole-4-yl)propenoic acid Chemical Properties,Usage,Production

Uses

trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function[1].

Definition

ChEBI: The trans-isomer of urocanic acid.

IC 50

Human Endogenous Metabolite

References

[1] J Uksila, et al. Trans-urocanic acid, a natural epidermal constituent, inhibits human natural killer cell activity in vitro. Exp Dermatol. 1994 Apr;3(2):61-5. DOI:10.1111/j.1600-0625.1994.tb00048.x
[2] Kazuyo Kaneko, et al. cis-Urocanic acid enhances prostaglandin E2 release and apoptotic cell death via reactive oxygen species in human keratinocytes. J Invest Dermatol. 2011 Jun;131(6):1262-71. DOI:10.1038/jid.2011.37

(2E)-3-(1H-Imidazole-4-yl)propenoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(2E)-3-(1H-Imidazole-4-yl)propenoic acid Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-66113011 17798518460
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(1)02557626880
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cfzhang@aikonchem.com
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China
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TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
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80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
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75
TCI AMERICA
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800-4238616
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+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
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9ding chemical ( Shanghai) Limited
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4009209199
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86-021-52271987
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sales@9dingchem.com
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China
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
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China
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Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
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Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
Email
xingui2022@126.com
Country
China
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9986
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View Lastest Price from (2E)-3-(1H-Imidazole-4-yl)propenoic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
(2E)-3-(1H-Imidazole-4-yl)propenoic acid 3465-72-3
Price
US $0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-01

3465-72-3, (2E)-3-(1H-Imidazole-4-yl)propenoic acidRelated Search:


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