1,3-Dithiane

ChemicalBook > CAS DataBase List > 1,3-Dithiane

Product Name: 1,3-Dithiane
CAS No.: 505-23-7
Chemical Name: 1,3-Dithiane
Synonyms: 1,3-Dithian;M-DITHIANE;1,3-DITHIANE;Dithiane-1,3;1,3-Dithane;META-DITHIANE;1,3-Dithiane>1,3-Dithiane,97%;1,3-Dithiane,99%;1,3-Dithiane,98%
CBNumber: CB6223805
Molecular Formula: C4H8S2
Formula Weight: 120.24
MOL File: 505-23-7.mol

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1,3-Dithiane Property

Melting point:: 52-54 °C (lit.)
Boiling point:: 207-208°C
Density: 1.062 (estimate)
refractive index: 1.5981 (estimate)
Flash point:: 195 °F
storage temp.: Inert atmosphere,Room Temperature
form: Crystals, Needles or Powder
pka: 31(at 25℃)
color: White to pale beige
Odor: at 0.01 % in propylene glycol. alliaceous roasted
Odor Type: alliaceous
Water Solubility: Soluble in benzene, ether, chloroform and terahydrofuran. Slightly soluble in water.
Sensitive: Hygroscopic
BRN: 102534
InChIKey: WQADWIOXOXRPLN-UHFFFAOYSA-N
LogP: 1.729 (est)
CAS DataBase Reference: 505-23-7(CAS DataBase Reference)
NIST Chemistry Reference: 1,3-Dithiane(505-23-7)

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Safety

Risk Statements: 20/21/22
Safety Statements: 22-24/25
RIDADR: UN 1325 4.1/PG 2
WGK Germany: 3
RTECS: JO5070000
F: 13
HazardClass: 4.1
PackingGroup: III
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H228Flammable solid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 157872
Product name: 1,3-Dithiane
Purity: 97%
Packaging: 5g
Price: $54.6
Updated: 2024/03/01

TCI Chemical

Product number: D0119
Product name: 1,3-Dithiane
Purity: >97.0%(GC)
Packaging: 5g
Price: $69
Updated: 2024/03/01

TCI Chemical

Product number: D0119
Product name: 1,3-Dithiane
Purity: >97.0%(GC)
Packaging: 25g
Price: $214
Updated: 2024/03/01

Alfa Aesar

Product number: A10505
Product name: 1,3-Dithiane, 98%
Packaging: 5g
Price: $47.65
Updated: 2024/03/01

Alfa Aesar

Product number: A10505
Product name: 1,3-Dithiane, 98%
Packaging: 25g
Price: $160.65
Updated: 2024/03/01

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1,3-Dithiane Chemical Properties,Usage,Production

Chemical Properties

white to pale beige crystals, needles or powder

Uses

1,3-Dithiane is used in umpolung reactions such as the Corey-Seebach reaction. It acts as a reagent for the deoxygenation of sulfoxides to their corresponding sulfides. Further, it is used as a protecting group for carbonyl compounds used in organic synthesis. It serves as a useful labeled synthon. In addition to this, it is used in the preparation of 2-ethyl-[1,3]dithiane.

Definition

ChEBI: 1,3-dithiane is a dithiane.

Reactions

1,3-dithiane has 2 weakly acidic protons that can be removed and alkylation of the carbon is possible. Once alkylated, the 1,3-dithiane becomes a “protected” carbonyl as it can be hydrolyzed to the corresponding carbonyl structure. Alternatively, the 1,3-dithiane moiety may also be introduced by thioacetalisation of a carbonyl group, either using acid or Lewis acid catalysis, 12 or of a 1,1-dihalide (using transition metal catalysis).

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 4477, 1988 DOI: 10.1016/S0040-4039(00)80527-4

General Description

1,3-Dithiane, a protected formaldehyde anion equivalent, serves as useful labeled synthon.

Purification Methods

Crystallise the 1,3-dithiane from 1.5 times its weight of MeOH at 0o, and sublime it at 40-50o/0.1mm. [Groel & Seebach Synthesis 357 1977, Beilstein 19/1 V 13.]

1,3-Dithiane Preparation Products And Raw materials

Raw materials

Potassium hydroxide solution Acetic acid Dimethoxymethane

Preparation Products

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1,3-Dithiane Suppliers

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View Lastest Price from 1,3-Dithiane manufacturers

JINING XINHE CHEMICAL CO., LTD

Product: 1,3-Dithiane 505-23-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10ton
Release date: 2024-07-15

Career Henan Chemical Co

Product: 1,3-Dithiane 505-23-7
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: ask
Release date: 2018-12-22

505-23-7, 1,3-DithianeRelated Search:

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505-23-7

C4H8S2

Building Blocks

Sulfur Compounds (for Synthesis)

Heterocyclic Building Blocks

S-Containing

Others

Allium sativum (Garlic)

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

Nutrition Research

Phytochemicals by Plant (Food/Spice/Herb)

Miscellaneous

Sulfur Compounds (for Synthesis)

Synthetic Organic Chemistry

Heterocyclic Building Blocks

Others

S-Containing

Sulfur