2,5-Dihydroxy-1,4-dithiane

Product Name: 2,5-Dihydroxy-1,4-dithiane
CAS No.: 40018-26-6
Chemical Name: 2,5-Dihydroxy-1,4-dithiane
Synonyms: 1,4-DITHIANE-2,5-DIOL;DITHIANE;p-Dithiane-2,5-diol;FEMA 3826;1,4-Dithiane-2,5-dio;1,4-dithane-2,5-diol;MERCATOACETALDEHYDE DIMER;DHDT;NSC 106280;4-dithiane
CBNumber: CB4141273
Molecular Formula: C4H8O2S2
Formula Weight: 152.24
MOL File: 40018-26-6.mol

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2,5-Dihydroxy-1,4-dithiane Property

Melting point:: 130 °C (dec.) (lit.)
Boiling point:: 244.73°C (rough estimate)
Density: 1.224 (estimate)
vapor pressure: 0Pa at 25℃
refractive index: 1.5200 (estimate)
FEMA: 3826 | 2,5-DIHYDROXY-1,4-DITHIANE
storage temp.: 2-8°C
solubility: H₂O: 0.39% at 20 °C
form: Crystalline Powder
pka: 12.04±0.40(Predicted)
color: White to yellow
PH: 4.9 (3.9g/l, H2O)
Odor: at 0.10 % in propylene glycol. sulfury meaty toasted bread broth egg tomato
Odor Type: sulfurous
Water Solubility: 3.9 g/L (20 ºC)
JECFA Number: 550
BRN: 104402
InChIKey: YUIOPHXTILULQC-UHFFFAOYSA-N
LogP: -0.276 at 22.8℃ and pH6.3
CAS DataBase Reference: 40018-26-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-41-43-52/53-36/37/38
Safety Statements: 26-36/37/39-61-37/39-24-36
RIDADR: UN2811
WGK Germany: 2
F: 1-8-10-13
HazardClass: 6.1
PackingGroup: III
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H317May cause an allergic skin reaction

H330Fatal if inhaled

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 183954
Product name: 1,4-Dithiane-2,5-diol
Purity: 97%
Packaging: 50g
Price: $52.5
Updated: 2023/01/07

Sigma-Aldrich

Product number: 183954
Product name: 1,4-Dithiane-2,5-diol
Purity: 97%
Packaging: 250g
Price: $115
Updated: 2023/01/07

TCI Chemical

Product number: D1761
Product name: 2,5-Dihydroxy-1,4-dithiane
Purity: >96.0%(GC)
Packaging: 25g
Price: $27
Updated: 2024/03/01

TCI Chemical

Product number: D1761
Product name: 2,5-Dihydroxy-1,4-dithiane
Purity: >96.0%(GC)
Packaging: 500g
Price: $320
Updated: 2024/03/01

Alfa Aesar

Product number: A14620
Product name: 2,5-Dihydroxy-1,4-dithiane, 96%
Packaging: 50g
Price: $27.65
Updated: 2024/03/01

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2,5-Dihydroxy-1,4-dithiane Chemical Properties,Usage,Production

Chemical Properties

2,5-Dihydroxy-1,4-dithiane has a sulfurous, meaty, toasted bread-like odor

Chemical Properties

white to yellowish crystalline powder

Uses

1,4-Dithiane-2,5-diol is a hydroxylated dithiane derivative with phytogrowth-inhibitory and antibacterial activities.

Uses

1,4-Dithiane-2,5-diol was used in the synthesis of:

substituted tetrahydrothiophene derivatives
2-amino-3-(arylsulfonyl)thiophenes, potential antiviral and antitumor agents

Definition

ChEBI: 1,4-Dithiane-2,5-diol is a member of dithianes.

Aroma threshold values

Aroma characteristics at 0.1% EtoH: sulfurous, grilled meaty, pungent, brothy, eggy, heavy and rich, toasted bread, tomato

Taste threshold values

Taste characteristics at 0.25 to 10 ppm: metallic, meaty savory chicken and beef, sulfurous, egg-yolk-like

Synthesis Reference(s)

Synthetic Communications, 14, p. 483, 1984 DOI: 10.1080/00397918408059569

General Description

1,4-Dithiane-2,5-diol undergoes bifunctional squaramide catalyzed sulfa-Michael/aldol cascade reaction with chalcones to afford trisubstituted tetrahydrothiophenes. It participates in diastereoselective [3+3] cycloaddition with azomethine imines catalyzed by 1,4-diazabicyclo[2.2.2]octane. It is a mercaptoacetaldehyde dimer and an efficient synthon for incorporating a thiol group to in situ generated nitroalkenes.

2,5-Dihydroxy-1,4-dithiane Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl 2-aminothiophene-3-carboxylate 3-METHOXYCARBONYL-3-SULFOLENE

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2,5-Dihydroxy-1,4-dithiane Suppliers

Americas 1 Belgium 2 Canada 2 China 388 Europe 5 France 1 Germany 9 India 29 Japan 4 Russia 1 Slovakia 1 South Korea 1 Switzerland 3 The Netherlands 2 Ukraine 2 United Kingdom 12 United States 32 USA 1 Global 496

Weifang Huitao Chemical Co., Ltd

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TCI (Shanghai) Development Co., Ltd.

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ShangHai DEMO Chemical Co.,Ltd

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View Lastest Price from 2,5-Dihydroxy-1,4-dithiane manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 2,5-Dihydroxy-1,4-dithiane 40018-26-6
Price: US $56.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-05-21

Hebei Weibang Biotechnology Co., Ltd

Product: 2,5-Dihydroxy-1,4-dithiane 40018-26-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-01

Hebei Chuanghai Biotechnology Co,.LTD

Product: 2,5-Dihydroxy-1,4-dithiane 40018-26-6
Price: US $9.50/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100ton
Release date: 2024-08-23

40018-26-6, 2,5-Dihydroxy-1,4-dithianeRelated Search:

Solvent Red 43 Triclosan 1,4-Butanediol DL-Dithiothreitol Chrysin Dimethyl disulfide 1-Hydroxyethylidene-1,1-diphosphonic acid 1,3-Dihydroxyacetone Butylated Hydroxytoluene Selenium sulfide 1,2-Pentanediol 3-Diethylaminophenol Ethyl 2-hydroxyethyl sulfide 4-Dithiane-2,5-diol,2,5-dimethyl- 1,4-Dithiane 1,2-Ethanedithiol 2-(3,4-Dimethoxyphenyl)-N-(3,4-dimethoxyphenethyl)-N-methyl-1,3-dithiane-2-propan-1-amine 1,1,3,3-tetraoxide trans-1,2-Dithiane-4,5-diol, Oxidized DTT,trans-1,2-dithiane-4,5-diol,trans-1,2-Dithiane-4,5-diol, Oxidized DTT,rel-(4R*,5R*)-1,2-Dithiane-4,5-diol

1,4-DITHIANE-2,5-DIOL

2,5-DIHYDROXY-1,4-DITHIANE

4-DITHIANE-2,5-DIOL

MERCATOACETALDEHYDE DIMER

p-Dithiane-2,5-diol, 95% 250GR

1,4-Dithiane-2,5-dio

1,4-Dithian-2,5-diol

NSC 106280

1,4-Dithiane-2,5-diol Mercaptoacetaldehyde Dimer

p-Dithiane-2,5-diol C4H8O2S2

Dihydroxy-1,4-dit

2,5-Dihydroxy-1,4-dithiane, 98%, Mixture of isoMers

1,4-DITHIANE-2,5-DIOL 2,5-DIHYDROXY-1,4-DITHIANE 4-DITHIANE-2,5-DIOL DITHIANE FEMA 3826

2,5-Dihydroxy-1,4-dithiane, Mixture of isoMers

2,5-Dihydroxy-1,4-Dithiance

2,5-Dihydroxy-1,4-dithiane, 97%, mixture of isomers

2.5- twohydroxytwo -1.4-dithiane

MERCAPTOACETALDEHYDE DIMER

DITHIANE

LABOTEST-BB LT00138118

FEMA 3826

p-Dithiane-2,5-diol

2 5-DIHYDROXY-1 4-DITHIANE 97+% MIXTU&

2,5-DIHYDROXY-1,4-DITHIANE, WACKERQUALIT Y

2,5-Dihydroxy-1,4-dithiane, pract., 95+%

2,5-DIHYDROXY-1,4-DITHIANE, 90+%

2,5-dimethyl-1,4-dithiane

tetrahydro-p-dithiin

1,4-dithane-2,5-diol

2,5-Dihydroxy-1,4-dithiane, Mercaptoacetaldehyde dimer

1,4-Dithiane-2,5-diol, 2,5-Dihydroxy-1,4-dithiane, Mercaptoacetaldehyde dimer

p-Dithiane-2,5-diol,95%

4-dithiane

5-Dihydroxy-1

(2S,5R)-1,4-dithiane-2,5-diol

2,5-Dihydroxy-1,4-dithiane&gt

2,5-Dihydroxy-1,4-dithiane[DHDT]

1, 4-dithio-2, 5-diol

2,5-Dihydroxy-1,4-dithiane, 97%+

p-Dithiane-2,5-diol, 96%,

2,5-Dihydroxy-1,4-Dithuane

1,4-Dithiane-2,5-diol (9CI, ACI)

2,5-Dihydroxy-1,4-dithiane/1,4-DITHIANE-2,5-DIOL

1,4-dithial-2,5-diol

DHDT

40018-26-6

CH2SCH2CH2SCH2

C4H8O2S2

C4H8O2S2C4H8O2S2C4H8O2S2C4H8O2S2

Heterocyclic Building Blocks

Others

S-Containing

Building Blocks

Heterocyclic Compounds

aldehyde Flavor

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks