ChemicalBook > CAS DataBase List > 2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDE
2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDE
- Product Name
- 2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDE
- CAS No.
- 849461-90-1
- Chemical Name
- 2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDE
- Synonyms
- TMPH;TMPH inhibitor;TMPH HYDROCHLORIDE;2,2,6,6-Tetramethylpiperidin-4-ylheptanoate;Heptanoic acid, 2,2,6,6-tetramethyl-4-piperidinyl ester;2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDE;neurol disorder,nAChR,Nicotinic acetylcholine receptors,neuronal nicotinic receptors,selective inhibition,Inhibitor,inhibit,nicotinic receptor,brain function,tetramethylpiperidinyl heptanoate,dysfunction
- CBNumber
- CB6227823
- Molecular Formula
- C16H31NO2
- Formula Weight
- 269.42
- MOL File
- 849461-90-1.mol
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2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDE Property
- storage temp.
- 2-8°C
- solubility
- H2O: 22 mg/mL at ~60 °C
- form
- solid
- color
- white
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-43
- Safety Statements
- 26-36/37
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2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
TMPH Hydrochloride is a potent inhibitor of neuronal AChRs. Therapeutic agent potentially used for the treatment of this progressive neurodegenerative disease such as globoid cell leukodystrophy (GLD) or Krabbe disease.
Definition
ChEBI: Heptanoic acid (2,2,6,6-tetramethyl-4-piperidinyl) ester is a fatty acid ester.
Biological Activity
Potent non-competitive antagonist of neuronal nicotinic ACh receptors (nAChRs). Produces long-lasting inhibition of neuronal nAChRs formed by the combination of the most abundant α and β subunits (i.e. α 3, α 4 and β 2, β 4 respectively). Displays little inhibition of muscle-type ( α 1 β 1 γ δ ) or α 7 receptors.
2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDE Suppliers
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849461-90-1, 2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDERelated Search:
2,2,6,6-TETRAMETHYLPIPERIDINOL-4 HYDROCHLORIDE
2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HEPTANOATE HYDROCHLORIDE