Glycohyocholic acid

Product Name: Glycohyocholic acid
CAS No.: 32747-08-3
Chemical Name: Glycohyocholic acid
Synonyms: Glycohyocholic acid;N-hyocholoylglycine;D4-Glycohyocholic Acid;Glyco-γ-muricholic acid;Glycohyocholic acid (GHCA);Hyocholic acid-glycine conjugate;N-(3α,6α,7α-Trihydroxy-24-oxo-5β-cholan-24-yl)glycine;N-(24-Oxo-3α,6α,7α-trihydroxy-5β-cholan-24-yl)glycine;Glycine, N-[(3α,5β,6α,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]-;5β-CHOLANIC ACID-3α, 6α, 7α-TRIOL N-(CARBOXYMETHYL)-AMIDE SODIUM SALT
CBNumber: CB62283944
Molecular Formula: C26H43NO6
Formula Weight: 465.63
MOL File: 32747-08-3.mol

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Glycohyocholic acid Property

Boiling point:: 673.4±55.0 °C(Predicted)
Density: 1.213±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form: A crystalline solid
pka: 3.58±0.10(Predicted)
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22670
Product name: Glycohyocholic Acid
Purity: ≥98%
Packaging: 500μg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 22670
Product name: Glycohyocholic Acid
Purity: ≥98%
Packaging: 1mg
Price: $115
Updated: 2024/03/01

Cayman Chemical

Product number: 22670
Product name: Glycohyocholic Acid
Purity: ≥98%
Packaging: 5mg
Price: $448
Updated: 2024/03/01

Cayman Chemical

Product number: 22670
Product name: Glycohyocholic Acid
Purity: ≥98%
Packaging: 10mg
Price: $774
Updated: 2024/03/01

TRC

Product number: G641395
Product name: GlycohyocholicAcid
Packaging: 5mg
Price: $1320
Updated: 2021/12/16

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Glycohyocholic acid Chemical Properties,Usage,Production

Description

Glycohyocholic acid (GHCA) is a glycine-conjugated form of the primary bile acid hyocholic acid . GHCA is upregulated 6.6-fold in the serum of patients with cirrhosis induced by hepatitis C virus (HCV) compared to healthy controls. Plasma levels of GHCA increase in patients who are no longer diabetic following gastric bypass surgery.

Uses

Glycohyocholic Acid is a bile salt.

Definition

ChEBI: Glycohyocholic acid is a bile acid glycine conjugate having hyocholic acid as the bile acid component. It has a role as a human metabolite. It is functionally related to a hyocholic acid. It is a conjugate acid of a glycohyocholate.

References

[1] LINING GUO. Plasma metabolomic profiles enhance precision medicine for volunteers of normal health.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2015: E4901-10. DOI: 10.1073/pnas.1508425112
[2] ASEM I. FITIAN. Integrated metabolomic profiling of hepatocellular carcinoma in hepatitis C cirrhosis through GC/MS and UPLC/MS-MS[J]. Liver International, 2014, 34 9: 1428-1444. DOI: 10.1111/liv.12541
[3] HAOYONG YU. Chenodeoxycholic Acid as a Potential Prognostic Marker for Roux-en-Y Gastric Bypass in Chinese Obese Patients.[J]. Journal of Clinical Endocrinology & Metabolism, 2015, 100 11: 4222-4230. DOI: 10.1210/jc.2015-2884

Glycohyocholic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Glycohyocholic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Glycohyocholic acid 32747-08-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-01

32747-08-3, Glycohyocholic acidRelated Search:

Glycohyocholic acid

N-(24-Oxo-3α,6α,7α-trihydroxy-5β-cholan-24-yl)glycine

N-(3α,6α,7α-Trihydroxy-24-oxo-5β-cholan-24-yl)glycine

2-[[(4R)-4-[(3R,5R,6R,7S,8S,9S,10R,13R,14S,17R)-3,6,7-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid

Glycohyocholic acid (GHCA)

Glycine, N-[(3α,5β,6α,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]-

5β-CHOLANIC ACID-3α, 6α, 7α-TRIOL N-(CARBOXYMETHYL)-AMIDE SODIUM SALT

Hyocholic acid-glycine conjugate

N-hyocholoylglycine

Glyco-γ-muricholic acid

D4-Glycohyocholic Acid

32747-08-3