Glycohyocholic acid
- Product Name
- Glycohyocholic acid
- CAS No.
- 32747-08-3
- Chemical Name
- Glycohyocholic acid
- Synonyms
- Glycohyocholic acid;N-hyocholoylglycine;D4-Glycohyocholic Acid;Glyco-γ-muricholic acid;Glycohyocholic acid (GHCA);Hyocholic acid-glycine conjugate;N-(3α,6α,7α-Trihydroxy-24-oxo-5β-cholan-24-yl)glycine;N-(24-Oxo-3α,6α,7α-trihydroxy-5β-cholan-24-yl)glycine;Glycine, N-[(3α,5β,6α,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]-;5β-CHOLANIC ACID-3α, 6α, 7α-TRIOL N-(CARBOXYMETHYL)-AMIDE SODIUM SALT
- CBNumber
- CB62283944
- Molecular Formula
- C26H43NO6
- Formula Weight
- 465.63
- MOL File
- 32747-08-3.mol
Glycohyocholic acid Property
- Boiling point:
- 673.4±55.0 °C(Predicted)
- Density
- 1.213±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
- form
- A crystalline solid
- pka
- 3.58±0.10(Predicted)
- color
- Off-white to light yellow
N-Bromosuccinimide Price
- Product number
- 22670
- Product name
- Glycohyocholic Acid
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 22670
- Product name
- Glycohyocholic Acid
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $115
- Updated
- 2024/03/01
- Product number
- 22670
- Product name
- Glycohyocholic Acid
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $448
- Updated
- 2024/03/01
- Product number
- 22670
- Product name
- Glycohyocholic Acid
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $774
- Updated
- 2024/03/01
- Product number
- G641395
- Product name
- GlycohyocholicAcid
- Packaging
- 5mg
- Price
- $1320
- Updated
- 2021/12/16
Glycohyocholic acid Chemical Properties,Usage,Production
Description
Glycohyocholic acid (GHCA) is a glycine-conjugated form of the primary bile acid hyocholic acid . GHCA is upregulated 6.6-fold in the serum of patients with cirrhosis induced by hepatitis C virus (HCV) compared to healthy controls. Plasma levels of GHCA increase in patients who are no longer diabetic following gastric bypass surgery.
Uses
Glycohyocholic Acid is a bile salt.
Definition
ChEBI: Glycohyocholic acid is a bile acid glycine conjugate having hyocholic acid as the bile acid component. It has a role as a human metabolite. It is functionally related to a hyocholic acid. It is a conjugate acid of a glycohyocholate.
References
[1] LINING GUO. Plasma metabolomic profiles enhance precision medicine for volunteers of normal health.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2015: E4901-10. DOI: 10.1073/pnas.1508425112
[2] ASEM I. FITIAN. Integrated metabolomic profiling of hepatocellular carcinoma in hepatitis C cirrhosis through GC/MS and UPLC/MS-MS[J]. Liver International, 2014, 34 9: 1428-1444. DOI: 10.1111/liv.12541
[3] HAOYONG YU. Chenodeoxycholic Acid as a Potential Prognostic Marker for Roux-en-Y Gastric Bypass in Chinese Obese Patients.[J]. Journal of Clinical Endocrinology & Metabolism, 2015, 100 11: 4222-4230. DOI: 10.1210/jc.2015-2884
Glycohyocholic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Glycohyocholic acid Suppliers
View Lastest Price from Glycohyocholic acid manufacturers
- Product
- Glycohyocholic acid 32747-08-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-01