ChemicalBook > CAS DataBase List > 5,4'-DIHYDROXYFLAVONE

5,4'-DIHYDROXYFLAVONE

Product Name
5,4'-DIHYDROXYFLAVONE
CAS No.
6665-67-4
Chemical Name
5,4'-DIHYDROXYFLAVONE
Synonyms
5-Dihydroxyflavone;5,4'-DIHYDROXYFLAVONE;4',5-Dihydroxyflavone;4',5-Dihydroxyflavone;5-Hydroxy-2-(4-hydroxyphenyl);4'',5-Dihydroxyflavone, 10 mM in DMSO;5-Hydroxy-2-(4-hydroxyphenyl)-4H-chroMen-4-one;4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-;Lipoxygenase,Glucosidase,LOX,4',5-Dihydroxyflavone,4',5 Dihydroxyflavone,inhibit,Inhibitor,4',5Dihydroxyflavone
CBNumber
CB6234481
Molecular Formula
C15H10O4
Formula Weight
254.24
MOL File
6665-67-4.mol
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5,4'-DIHYDROXYFLAVONE Property

Melting point:
239-240°C
Boiling point:
486.0±45.0 °C(Predicted)
Density 
1.443±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 155 mg/mL (609.66 mM);Water : < 0.1 mg/mL (insoluble)
pka
6.78±0.40(Predicted)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D679110
Product name
4'',5-Dihydroxyflavone
Packaging
1g
Price
$240
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD66316
Product name
4',5-Dihydroxyflavone
Packaging
500mg
Price
$55
Updated
2021/12/16
ChemScene
Product number
CS-0017766
Product name
4',5-Dihydroxyflavone
Purity
95.75%
Packaging
100mg
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD66316
Product name
4',5-Dihydroxyflavone
Packaging
1g
Price
$102
Updated
2021/12/16
AK Scientific
Product number
W1616
Product name
4',5-Dihydroxyflavone
Packaging
10mg
Price
$117
Updated
2021/12/16
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5,4'-DIHYDROXYFLAVONE Chemical Properties,Usage,Production

Uses

4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase. LOX-1 isshort for Lectin-like oxidized low-density lipoprotein receptor-1.

References

[1] Ribeiro D, et al. Inhibition of LOX by flavonoids: a structure-activity relationship study. Eur J Med Chem. 2014 Jan 24;72:137-45. DOI:10.1016/j.ejmech.2013.11.030
[2] Proen?a C, et al. α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study. J Enzyme Inhib Med Chem. 2017 Dec;32(1):1216-1228. DOI:10.1080/14756366.2017.1368503

5,4'-DIHYDROXYFLAVONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6665-67-4, 5,4'-DIHYDROXYFLAVONERelated Search:


  • 5,4'-DIHYDROXYFLAVONE
  • 5-Hydroxy-2-(4-hydroxyphenyl)-4H-chroMen-4-one
  • 5-Hydroxy-2-(4-hydroxyphenyl)
  • 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-
  • 5-Dihydroxyflavone
  • Lipoxygenase,Glucosidase,LOX,4',5-Dihydroxyflavone,4',5 Dihydroxyflavone,inhibit,Inhibitor,4',5Dihydroxyflavone
  • 4',5-Dihydroxyflavone
  • 4'',5-Dihydroxyflavone, 10 mM in DMSO
  • 4',5-Dihydroxyflavone
  • 6665-67-4
  • Di-substituted Flavones