ChemicalBook > CAS DataBase List > 5,4'-DIHYDROXYFLAVONE
5,4'-DIHYDROXYFLAVONE
- Product Name
- 5,4'-DIHYDROXYFLAVONE
- CAS No.
- 6665-67-4
- Chemical Name
- 5,4'-DIHYDROXYFLAVONE
- Synonyms
- 5-Dihydroxyflavone;5,4'-DIHYDROXYFLAVONE;4',5-Dihydroxyflavone;4',5-Dihydroxyflavone;5-Hydroxy-2-(4-hydroxyphenyl);4'',5-Dihydroxyflavone, 10 mM in DMSO;5-Hydroxy-2-(4-hydroxyphenyl)-4H-chroMen-4-one;4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-;Lipoxygenase,Glucosidase,LOX,4',5-Dihydroxyflavone,4',5 Dihydroxyflavone,inhibit,Inhibitor,4',5Dihydroxyflavone
- CBNumber
- CB6234481
- Molecular Formula
- C15H10O4
- Formula Weight
- 254.24
- MOL File
- 6665-67-4.mol
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5,4'-DIHYDROXYFLAVONE Property
- Melting point:
- 239-240°C
- Boiling point:
- 486.0±45.0 °C(Predicted)
- Density
- 1.443±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : ≥ 155 mg/mL (609.66 mM);Water : < 0.1 mg/mL (insoluble)
- pka
- 6.78±0.40(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
TRC
- Product number
- D679110
- Product name
- 4'',5-Dihydroxyflavone
- Packaging
- 1g
- Price
- $240
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FD66316
- Product name
- 4',5-Dihydroxyflavone
- Packaging
- 500mg
- Price
- $55
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0017766
- Product name
- 4',5-Dihydroxyflavone
- Purity
- 95.75%
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FD66316
- Product name
- 4',5-Dihydroxyflavone
- Packaging
- 1g
- Price
- $102
- Updated
- 2021/12/16
AK Scientific
- Product number
- W1616
- Product name
- 4',5-Dihydroxyflavone
- Packaging
- 10mg
- Price
- $117
- Updated
- 2021/12/16
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5,4'-DIHYDROXYFLAVONE Chemical Properties,Usage,Production
Uses
4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase. LOX-1 isshort for Lectin-like oxidized low-density lipoprotein receptor-1.
References
[1] Ribeiro D, et al. Inhibition of LOX by flavonoids: a structure-activity relationship study. Eur J Med Chem. 2014 Jan 24;72:137-45. DOI:10.1016/j.ejmech.2013.11.030
[2] Proen?a C, et al. α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study. J Enzyme Inhib Med Chem. 2017 Dec;32(1):1216-1228. DOI:10.1080/14756366.2017.1368503
5,4'-DIHYDROXYFLAVONE Preparation Products And Raw materials
Raw materials
Preparation Products
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