ChemicalBook > CAS DataBase List > 2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE

2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE

Product Name
2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE
CAS No.
4943-85-5
Chemical Name
2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE
Synonyms
OTAVA-BB 1133397;2-Amino-benzoesaeure-o-toluidid;N-(2-Aminobenzoyl)-2-methylaniline;2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE;BENZAMIDE, 2-AMINO-N-(2-METHYLPHENYL)-
CBNumber
CB6238085
Molecular Formula
C14H14N2O
Formula Weight
226.27
MOL File
4943-85-5.mol
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2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE Property

Melting point:
104-105 °C
Boiling point:
320.2±35.0 °C(Predicted)
Density 
1.210±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
13.25±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R702153
Product name
2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE
Purity
AldrichCPR
Packaging
25MG
Price
$30.7
Updated
2025/07/31
ChemScene
Product number
CS-0038876
Product name
2-Amino-N-(2-methylphenyl)benzamide
Packaging
25g
Price
$56
Updated
2021/12/16
Matrix Scientific
Product number
157206
Product name
2-Amino-N-(2-methylphenyl)benzamide
Packaging
0.500g
Price
$120
Updated
2021/12/16
ChemScene
Product number
CS-0038876
Product name
2-Amino-N-(2-methylphenyl)benzamide
Packaging
100g
Price
$135
Updated
2021/12/16
AK Scientific
Product number
6693AB
Product name
2-Amino-N-(o-tolyl)benzamide
Packaging
1g
Price
$10
Updated
2021/12/16
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2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE Chemical Properties,Usage,Production

Synthesis

2385-25-3

4943-85-5

Nitrobenzene (0.6 mmol) was used as a feedstock and mixed with 5 wt% Pd/C (0.5 mol%, 0.003 mmol), H2O (10 eq, 6.0 mmol), B2(OH)4 (3.3 eq, 2.0 mmol) and CH3CN (1.0 mL) in a 10 mL reaction tube. The reaction mixture was stirred at 50 °C for 24 hours. The reaction progress was monitored by TLC. After completion of the reaction, the mixture was cooled to room temperature. Water (5 mL) was added and extracted with EtOAc (3 x 5 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to afford the target product 2-amino-N-(o-toluene)benzamide (55 mg, 99% yield).

References

[1] Tetrahedron, 2017, vol. 73, # 27-28, p. 3898 - 3904
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 8, p. 2400 - 2411
[3] RSC Advances, 2016, vol. 6, # 33, p. 27378 - 27387
[4] Synlett, 2018, vol. 29, # 13, p. 1765 - 1768
[5] Journal of Medicinal Chemistry, 1986, vol. 29, # 8, p. 1534 - 1537

2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE Suppliers

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View Lastest Price from 2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
N-(2-Aminobenzoyl)-2-methylaniline 4943-85-5
Price
US $1.00-2.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
20000KG
Release date
2024-08-14
Career Henan Chemical Co
Product
2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE 4943-85-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-12-20

4943-85-5, 2-AMINO-N-(2-METHYLPHENYL)BENZAMIDERelated Search:

METHAQUALONE HYDROCHLORIDE Metolazone METHAQUALONE Benzamide TRYPTANTHRIN 4-AMINO-2-O-TOLYL-ISOINDOLE-1,3-DIONE 2-amino-N-(2,6-dimethylphenyl)benzamide 2-AMINO-N-(2,4-DIMETHYLPHENYL)BENZAMIDE piriqualone N-[5-(5,7-DIMETHYL-BENZOOXAZOL-2-YL)-2-METHYL-PHENYL]-2,4-DINITRO-BENZAMIDE 2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE 2-[(BUTYLSULFANYL)METHYL]-6,8-DICHLORO-3-(2,6-DIMETHYLPHENYL)-4(3H)-QUINAZOLINONE 2-(DICHLOROMETHYL)-3-(2,4-DIMETHYLPHENYL)-2-METHYL-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE 2-[(BENZYLSULFANYL)METHYL]-6,8-DICHLORO-3-(2,6-DIMETHYLPHENYL)-4(3H)-QUINAZOLINONE 6,8-DICHLORO-3-(2,6-DIMETHYLPHENYL)-2-(([3-(TRIFLUOROMETHYL)PHENYL]SULFANYL)METHYL)-4(3H)-QUINAZOLINONE 2-([(4-BROMOPHENYL)SULFANYL]METHYL)-6,8-DICHLORO-3-(2,6-DIMETHYLPHENYL)-4(3H)-QUINAZOLINONE 2-AMINO-N-(4-CHLORO-2-METHYLPHENYL)BENZAMIDE N-(2-CYANOPHENYL)-2-NITROBENZAMIDE

  • BENZAMIDE, 2-AMINO-N-(2-METHYLPHENYL)-
  • OTAVA-BB 1133397
  • 2-AMINO-N-(2-METHYLPHENYL)BENZAMIDE
  • 2-Amino-benzoesaeure-o-toluidid
  • N-(2-Aminobenzoyl)-2-methylaniline
  • 4943-85-5