ChemicalBook > CAS DataBase List > ISOCORYDINE HYDROCHLORIDE

ISOCORYDINE HYDROCHLORIDE

Product Name
ISOCORYDINE HYDROCHLORIDE
CAS No.
475-67-2
Chemical Name
ISOCORYDINE HYDROCHLORIDE
Synonyms
luteanin;LUTEANINE;artabotrin;Aids138466;Uzokoridin;Isocorydine;Aids-138466;d-isocorydine;l-(+)-isocorydine;S-ISOCORYDINE (+)
CBNumber
CB6238999
Molecular Formula
C20H23NO4
Formula Weight
341.4
MOL File
475-67-2.mol
More
Less

ISOCORYDINE HYDROCHLORIDE Property

Melting point:
216-220 °C(lit.)
alpha 
D20 +195° (chloroform)
Boiling point:
477.03°C (rough estimate)
Density 
1.2064 (rough estimate)
refractive index 
1.5614 (estimate)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Cryst.
pka
9.41±0.20(Predicted)
More
Less

Safety

WGK Germany 
3
RTECS 
CE1057950
Toxicity
LD50 intraperitoneal in mouse: 104mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
30101
Product name
Isocorydine
Packaging
10mg
Price
$56
Updated
2024/03/01
Cayman Chemical
Product number
30101
Product name
Isocorydine
Packaging
25mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
30101
Product name
Isocorydine
Packaging
5mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
30101
Product name
Isocorydine
Packaging
50mg
Price
$178
Updated
2024/03/01
Usbiological
Product number
361810
Product name
Isocorydine
Packaging
20mg
Price
$546
Updated
2021/12/16
More
Less

ISOCORYDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Isocorydine is an aporphine alkaloid that has been found in A. squamosa that has vasodilatory and anticancer activities. It reduces the action potential duration and increases the effective refractory period in isolated canine Purkinje fibers when used at a concentration of 30 μM. Isocorydine induces relaxation of norepinephrine-precontracted isolated rabbit aortic strips with an EC50 value of 12.6 μM. It is cytotoxic to A549 lung cancer cells (IC50 = 197.7 μM), as well as Huh7, HepG2, SNU-449, and SNU-387 hepatic cancer cells (IC50s = 161.3, 148, 262.2, and 254.1 μg/ml, respectively). Isocorydine, in combination with doxorubicin, reduces tumor growth in a Huh7 mouse xenograft model.

Uses

Isocorydine Hydrochloride is the hydrochloric acid of Isocorydine(I797000) which is an alkaloid inhibitor of eukaryotic kinases.

Uses

sedative, cholinergic

Uses

Isocorydine is an alkaloid inhibitor of eukaryotic kinases.

Definition

ChEBI: Isocorydine is an aporphine alkaloid.

target

Dopamine Receptor | P450 (e.g. CYP17)

References

See Isocorydine

ISOCORYDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ISOCORYDINE HYDROCHLORIDE Suppliers

China 124 Germany 1 Switzerland 3 Ukraine 1 United Kingdom 7 United States 16 Global 152
Spectrum Info. Ltd.
Tel
--
Fax
--
Email
spectrum@kv.ukrtel.net
Country
Ukraine
ProdList
2741
Advantage
53
More
Less

View Lastest Price from ISOCORYDINE HYDROCHLORIDE manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Isocorydine 475-67-2
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
100 g
Release date
2020-08-19
Career Henan Chemical Co
Product
ISOCORYDINE HYDROCHLORIDE 475-67-2
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

475-67-2, ISOCORYDINE HYDROCHLORIDERelated Search:

(S)-1-(3,4-Dimethoxyphenyl)ethylamine 2-METHOXYBIPHENYL 1-BIPHENYL-2-YL-N-METHYLMETHYLAMINE 4-CHLORO-2-FLUOROBENZYLAMINE HYDROCHLORIDE ISOCORYDINE HYDROCHLORIDE ISOCORYDINE HYDROCHLORIDE (S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol 2,6-Dimethylbenzylamine 3,4,5-TRIMETHYLPHENOL 2,2'-Biphenol 3-[(1S)-1-(Dimethylaminoethyl)]phenol (S)-7-METHOXY-1-METHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL (R)-4-(1-Aminoethyl)phenol (S)-hydroxybutanedioate salt SALSOLIDINE 2,6-DIMETHYL-4-HYDROXYBENZYLAMINE (S)-o-Methyl-a-phenylethylamine 8-methyl-1,2,3,4-tetrahydroisoquinoline 6,7-DIMETHOXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE

  • LUTEANINE
  • LUTEANINE HYDROCHLORIDE
  • 1,2,10-trimethoxy-6a-alpha-aporphin-11-o
  • 4h-dibenzo(de,g)quinolin-11-ol,5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methy
  • artabotrin
  • d-isocorydine
  • l-(+)-isocorydine
  • luteanin
  • luteanine(aporphine)
  • D-ISOCORYDINE HYDROCHLORIDE
  • (+)-ISOCORYDINE HCL
  • ISOCORYDINE HCL, (+)-
  • (+)-ISOCORYDINE HYDROCHLORIDE
  • ISOCORYDINE HYDROCHLORIDE
  • (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol
  • 11-HYDROXY-1,2,10-TRIMETHOXYAPORPHINE
  • 11-HYDROXY-1,2,10-TRIMETHOXYAPORPHINE HYDROCHLORIDE
  • (+)-Isocorynoline hydrochloride
  • (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-11-ol
  • [6aS,(+)]-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-11-ol
  • Isocorydine
  • S-ISOCORYDINE (+)
  • 1,2,10-Trimethoxy-6-methyl-5,6,6A,7-tetrahydro-4H-dibenzo[de,G]quinolin-11-ol
  • Aids138466
  • Aids-138466
  • Aporphin-11-ol, 1,2,10-trimethoxy-
  • (+)-isocorynoline
  • Uzokoridin
  • 4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6aS)-
  • Artabotrin|||S-Isocorydine(+)|||Luteanin|||Uzokoridin|||(+)-Isocorynoline
  • 475-67-2
  • Analytical Chromatography Product Catalog
  • Analytical Standards
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Others
  • Drug Standards
  • Chromatography
  • Forensic and Veterinary Standards
  • Heterocyclic Building Blocks
  • Inhibitors
  • Miscellaneous Natural Products
  • Alkaloids