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Teicoplanin A3-1

Product Name
Teicoplanin A3-1
CAS No.
93616-27-4
Chemical Name
Teicoplanin A3-1
Synonyms
L 17054;Teicoplanin A3-1;Teicoplanin A3-1 DISCONTINUED. Please see T015500;34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-α-D-mannopyranosyl-ristomycinAaglycone;Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-α-D-mannopyranosyl-
CBNumber
CB62436968
Molecular Formula
C72H68Cl2N8O28
Formula Weight
1564.25
MOL File
93616-27-4.mol
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Teicoplanin A3-1 Property

Density 
1.80±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in ethanol;Soluble in methanol;Soluble in DMSO;Soluble in dimethyl formamide
form 
solid
pka
2.88±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20193
Product name
Teicoplanin A3-1
Purity
≥98%
Packaging
1mg
Price
$242
Updated
2024/03/01
Cayman Chemical
Product number
20193
Product name
Teicoplanin A3-1
Purity
≥98%
Packaging
5mg
Price
$846
Updated
2024/03/01
ApexBio Technology
Product number
C4943
Product name
TeicoplaninA3-1
Packaging
5mg
Price
$966
Updated
2021/12/16
ApexBio Technology
Product number
C4943
Product name
TeicoplaninA3-1
Packaging
1mg
Price
$276
Updated
2021/12/16
AK Scientific
Product number
2702CW
Product name
TeicoplaninA3-1
Packaging
1mg
Price
$368
Updated
2021/12/16
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Teicoplanin A3-1 Chemical Properties,Usage,Production

Uses

Teicoplanin A3-1 is a minor polar analogue of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad spectrum antibiotic activity against Gram positive bacteria, including MRSA and E. faecalis. Teicoplanin A3-1 is the common degradation product of teicoplanins A2-1 to 5, resulting from cleavage of the lipoaminoglycoside substituents.

Uses

Teicoplanin A3-1 is an antibiotic against Gram positive bacteria.

Definition

ChEBI: A glycopeptide consisting of a macropolycyclic heptapeptide in which a phenolic hydroxy group has been converted to its alpha-D-mannoside while a secondary alcohol group has been converted to the corresponding 2-acetamido- -deoxy-beta-D-glucoside.

Biological Activity

teicoplanin a3-1, also known as antibiotic l 17054, is a glycopeptide antibiotic derived from actinoplanes teichomyceticus and produces a potent broad spectrum antibiotic activity against gram-positive bacteria.teicoplanin a3-1 is a common degradation product of teicoplanins a2-1 to 5, which results from cleavage of the lipoaminoglycoside substituents. teicoplanins are glycopeptide antibiotics produced by a. teichomyceticus which are effective against gram-positive bacteria, including methicillin-resistant staphylococcus aureus (mrsa) and e. faecalis. as an antibiotic complex, teicoplanin consists of five closely related factors, t-a2-1, 2, 3, 4 and 5 and a more polar factor, t-a3-1. additionally, as a glycopeptide antibiotic belonging to the same family as vancomycin, teicoplanin blocks cell wall synthesis in bacillus subtilis, which is accompanied by an intracellular accumulation of udp-n-acetylmuramyl-pentapetide [1]. due to the greater antibacterial activity of teicoplanin than other agents, it has been thoroughly studied as a β-1actamase-resistant agent for the treatment of human infections caused by streptococci and staphylococci, including enterococci [2].

References

[1]. somma, s., gastaldo, l., & corti, a. teicoplanin, a new antibiotic from actinoplanes teichomyceticus nov. sp. antimicrobial agents and chemotherapy. 1984; 26(6): 917-923.
[2]. traina, g., & bonati, m. pharmacokinetics of teicoplanin in man after intravenous administration. journal of pharmacokinetics and biopharmaceutics. 1984;12(2): 119-128.

Teicoplanin A3-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Teicoplanin A3-1 Suppliers

ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17994
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56
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
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Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
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China
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Novachemistry
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44-20819178-90 02081917890
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(0)2080432064
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info@novachemistry.com
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United Kingdom
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4381
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
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China
ProdList
55896
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Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
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28180
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58
BOC Sciences
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+1-631-485-4226
Fax
1-631-614-7828
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inquiry@bocsci.com
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United States
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19553
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Meng Cheng Technology (Shanghai) Co., LTD
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400-820-6829
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sales@mitachieve.com
Country
China
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8864
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58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8141
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58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12664
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58

93616-27-4, Teicoplanin A3-1Related Search:


  • Teicoplanin A3-1
  • L 17054
  • Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-α-D-mannopyranosyl-
  • Teicoplanin A3-1 DISCONTINUED. Please see T015500
  • 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-α-D-mannopyranosyl-ristomycinAaglycone
  • 93616-27-4
  • C72H68Cl2N8O28