Coluracetam

Product Name: Coluracetam
CAS No.: 135463-81-9
Chemical Name: Coluracetam
Synonyms: BCI-540;COLURACETAM;Colurac tam;MKC-231;BCI-540;Coluracetam, >=99%;Coluracetam, MKC-231;COLURACETAM USP/EP/BP;top quality Coluracetam;MKC-231; MKC231; MKC 231;CAS135463-81-9 COLURACETAM
CBNumber: CB62446491
Molecular Formula: C19H23N3O3
Formula Weight: 341.4
MOL File: 135463-81-9.mol

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Coluracetam Property

Boiling point:: 634.1±55.0 °C(Predicted)
Density: 1.291±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMF: 1 mg/ml; DMSO: 2 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): insol
form: A crystalline solid
pka: 12.01±0.20(Predicted)
InChI: InChI=1S/C19H23N3O3/c1-11-12(2)25-19-17(11)18(13-6-3-4-7-14(13)20-19)21-15(23)10-22-9-5-8-16(22)24/h3-10H2,1-2H3,(H,20,21,23)
InChIKey: PSPGQHXMUKWNDI-UHFFFAOYSA-N
SMILES: N1(CC(NC2C3=C(N=C4OC(C)=C(C)C4=2)CCCC3)=O)CCCC1=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

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N-Bromosuccinimide Price

ChemScene

Product number: CS-2196
Product name: Coluracetam
Purity: 99.87%
Packaging: 10mg
Price: $60
Updated: 2021/12/16

ApexBio Technology

Product number: B1158
Product name: Coluracetam
Packaging: 10mg
Price: $79
Updated: 2021/12/16

ChemScene

Product number: CS-2196
Product name: Coluracetam
Purity: 99.87%
Packaging: 50mg
Price: $80
Updated: 2021/12/16

ChemScene

Product number: CS-2196
Product name: Coluracetam
Purity: 99.87%
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-2196
Product name: Coluracetam
Purity: 99.87%
Packaging: 100mg
Price: $90
Updated: 2021/12/16

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Coluracetam Chemical Properties,Usage,Production

Uses

Copiracetam can be used as a nootropic drug to treat memory and intellectual impairments caused by senile dementia, mild to moderate vascular dementia, trauma and other diseases, and to promote children's intellectual development; it also has antidepressant effects.

Pharmacology

Copiracetam has the ability to improve cognition by participating in the HACU process, increasing the rate-limiting step of synaptic intake of choline to synthesize the neurotransmitter acetylcholine, and increasing the activity of cholinergic neurons.

in vitro

Coluracetam (10(-10)-10(-6) moll), also known as MKC-231, significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding.

in vivo

Oral administration of MKC-231 (Coluracetam; 1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested.

Coluracetam Preparation Products And Raw materials

Raw materials

Preparation Products

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Coluracetam Suppliers

China 193 Europe 1 India 2 Japan 1 United States 11 Global 208

Wuhan HengHeDa Pharm Co., Ltd.

Tel: 27-27-84888682 18086046872
Fax: 027-84888682
Email: hhdpharm@hotmail.com
Country: China
ProdList: 117
Advantage: 55

Hefei Chaobo Technology Co., Ltd

Tel: 19322001459
Email: zb19922001456@163.com
Country: China
ProdList: 475
Advantage: 58

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5700
Advantage: 66

Wuhan Sunrise Technology Development Co., Ltd.

Tel: 027-027-83314682 13554138826
Fax: +86 (27) 8331-4682
Email: whsrtech@vip.163.com
Country: China
ProdList: 300
Advantage: 62

Wuhan Vanzpharm Inc.

Tel: 027-84492310 13657243668
Fax: 027-84492310
Email: wangting@vanzpharm.com
Country: China
ProdList: 53
Advantage: 58

Heterochem

Tel: 027-88041443 13072715837
Fax: 027-51829379
Email: sales@hetero-chem.com
Country: China
ProdList: 696
Advantage: 58

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1494
Advantage: 55

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9901
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Fax: +86-25-52131256
Email: 799750417@qq.com
Country: China
ProdList: 8888
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

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View Lastest Price from Coluracetam manufacturers

Wuhan Cell Pharmaceutical Co., Ltd

Product: Coluracetam 135463-81-9
Price: US $2.00-1.50/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2023-04-11

Wuhan Haorong Biotechnology Co.,Ltd

Product: COLURACETAM 135463-81-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000
Release date: 2023-08-11

Hebei Dangtong Import and export Co LTD

Product: COLURACETAM 135463-81-9
Price: US $108.00-104.00/Grams
Min. Order: 50Grams
Purity: 99.99%
Supply Ability: 100Tons
Release date: 2023-03-17

135463-81-9, ColuracetamRelated Search:

Choline bitartrate CYCLAZOSIN HYDROCHLORIDE Acetamide,N-(2-methyl-4-pyridinyl)- Coluracetam CHEMBRDG-BB 4014008

COLURACETAM

N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide

1-Pyrrolidineacetamide,2-oxo-N-(5,6,7,8-tetrahydro-2,3-dimethylfuro[2,3-b]quinolin-4-yl)-

Coluracetam, MKC-231

1-[N-(2,3-DiMethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)carbaMoylMethyl]pyrrolidin-2-one

BCI-540

Coluracetam, >=99%

2-oxo-N-(5,6,7,8-tetrahydro-2,3-dimethyl-furo[2,3-b]quinolin-4-yl)-1-pyrrolidineacetamide

coluracetam cas: 135463-81-9

MKC-231;BCI-540

MKC-231; MKC231; MKC 231

top quality Coluracetam

COLURACETAM USP/EP/BP

CAS135463-81-9 COLURACETAM

Furo(2,3-b)quinoline-1-pyrrolidineacetamide Deriv

COLURACETAM MKC-231 BCI-540

Colurac tam

135463-81-9

Brain health drug

Nootropic

pharmaceutical intermediate or medicine grade

pharmaceutical