(2-BROMO-6-FLUOROPHENYL)METHANOL
Uses- Product Name
- (2-BROMO-6-FLUOROPHENYL)METHANOL
- CAS No.
- 261723-33-5
- Chemical Name
- (2-BROMO-6-FLUOROPHENYL)METHANOL
- Synonyms
- 2-Bromo-6-fluorobenzyl alcohol;6-Bromo-2-fluorobenzyl alcohol;2-bromo-6-fluoroBenzenemethanol;(2-BROMO-6-FLUOROPHENYL)METHANOL;BenzeneMethanol, 2-broMo-6-fluoro-
- CBNumber
- CB62449432
- Molecular Formula
- C7H6BrFO
- Formula Weight
- 205.02
- MOL File
- 261723-33-5.mol
(2-BROMO-6-FLUOROPHENYL)METHANOL Property
- Melting point:
- 40-60°
- Boiling point:
- 256.7±25.0 °C(Predicted)
- Density
- 1.658±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 13.47±0.10(Predicted)
- form
- solid
- color
- White
- InChI
- InChI=1S/C7H6BrFO/c8-6-2-1-3-7(9)5(6)4-10/h1-3,10H,4H2
- InChIKey
- HHGJENWYHVFPSA-UHFFFAOYSA-N
- SMILES
- C1(CO)=C(F)C=CC=C1Br
Safety
- HS Code
- 2906290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B692105
- Product name
- 2-Bromo-6-fluorobenzylalcohol
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- B692105
- Product name
- 2-Bromo-6-fluorobenzylalcohol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 2701-B-01
- Product name
- 2-Bromo-6-fluorobenzyl alcohol
- Packaging
- 5G
- Price
- $48
- Updated
- 2021/12/16
- Product number
- HCH0036852
- Product name
- (2-BROMO-6-FLUOROPHENYL)METHANOL
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $909.56
- Updated
- 2021/12/16
- Product number
- CS-W006374
- Product name
- (2-Bromo-6-fluorophenyl)methanol
- Purity
- 99.86%
- Packaging
- 10g
- Price
- $67
- Updated
- 2021/12/16
(2-BROMO-6-FLUOROPHENYL)METHANOL Chemical Properties,Usage,Production
Uses
2-Bromo-6-fluorobenzyl alcohol is an important pharmaceutical intermediate.
Synthesis
360575-28-6
261723-33-5
General procedure for the synthesis of 2-fluoro-6-bromobenzenemethanol from 2-bromo-6-fluorobenzaldehyde: Sodium borohydride (284 g, 7.93 mol) was added batchwise to a solution of 2-bromo-6-fluorobenzaldehyde (1.60 kg, 7.91 mol) in methanol (14 L) at 0 °C, with a controlled rate of addition to regulate exothermic and gas production. After 15 minutes of reaction, the reaction was quenched with water (500 mL) and the reaction mixture was subsequently concentrated to give a yellow oil. The oil was dissolved in ethyl acetate (6L) and washed with (3L) water. The aqueous layer was back-extracted with ethyl acetate (1L). The organic phases were combined, washed with brine (2L), dried over anhydrous sodium sulfate, filtered and concentrated to give 2-fluoro-6-bromobenzenemethanol as an orange oil (1614 g, 100%). The product was characterized by 1H NMR (CDCl3): δ 7.40 (d, 1H), 7.18 (m, 1H), 7.07 (t, 1H), 4.86 (s, 2H).
References
[1] Patent: US2009/163472, 2009, A1. Location in patent: Page/Page column 18
[2] Patent: US2011/65727, 2011, A1. Location in patent: Page/Page column 16
[3] Patent: US2011/65699, 2011, A1. Location in patent: Page/Page column 14
[4] Advanced Synthesis and Catalysis, 2014, vol. 356, # 16, p. 3415 - 3421
(2-BROMO-6-FLUOROPHENYL)METHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
(2-BROMO-6-FLUOROPHENYL)METHANOL Suppliers
- Tel
- 400-106-2016 17800804092
- admin@infsci.com
- Country
- China
- ProdList
- 555
- Advantage
- 55
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- 18652989687
- Fax
- +86-25-52131256
- sales@norris-pharm.com
- Country
- China
- ProdList
- 8878
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- +86-18068513926
- Fax
- 0086-519-85153711
- Country
- China
- ProdList
- 1277
- Advantage
- 55
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- 1822-2954721 15901640172
- Fax
- 0731-57805668
- sales03@hn-furui.com
- Country
- China
- ProdList
- 421
- Advantage
- 55
- Tel
- 18622448868
- Fax
- 022-58620773
- jpjchem@163.com
- Country
- China
- ProdList
- 490
- Advantage
- 62
View Lastest Price from (2-BROMO-6-FLUOROPHENYL)METHANOL manufacturers
- Product
- 2-Bromo-6-fluorobenzyl alcohol 261723-33-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-17
- Product
- 2-Bromo-6-fluorobenzyl alcohol 261723-33-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2023-06-09
- Product
- (2-BROMO-6-FLUOROPHENYL)METHANOL 261723-33-5
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 50000tons
- Release date
- 2023-08-08