6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE

Product Name: 6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE
CAS No.: 167158-70-5
Chemical Name: 6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE
Synonyms: 6-Bromo-2-chloroquinazolin-4-ol;6-Bromo-2-chloroquinazolin-4(3H);2-Chloro-6-broMoquinazolin-4(3H)-one;6-Bromo-2-chloro-4(3H)-quinazolinone;6-bromo-2-chloroquinazolin-4(3H)-one;6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE;4(3H)-Quinazolinone, 6-bromo-2-chloro-;6-bromo-2-chloro-3,4-dihydroquinazolin-4-one
CBNumber: CB62455912
Molecular Formula: C8H4BrClN2O
Formula Weight: 259.49
MOL File: 167158-70-5.mol

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6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE Property

Boiling point:: 393.2±44.0 °C(Predicted)
Density: 1.95
storage temp.: 2-8°C, stored under nitrogen, away from moisture
pka: -3.76±0.20(Predicted)
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C8H4BrClN2O/c9-4-1-2-6-5(3-4)7(13)12-8(10)11-6/h1-3H,(H,11,12,13)
InChIKey: WZVAPPYRAGWFKW-UHFFFAOYSA-N
SMILES: N1C2=C(C=C(Br)C=C2)C(=O)NC=1Cl

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: 8514AA
Product name: 6-Bromo-2-chloroquinazolin-4(3H)-one
Packaging: 100mg
Price: $328
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0367714
Product name: 6-BROMO-2-CHLOROQUINAZOLIN-4(3H)-ONE
Purity: 95.00%
Packaging: 5MG
Price: $496.46
Updated: 2021/12/16

AK Scientific

Product number: 8514AA
Product name: 6-Bromo-2-chloroquinazolin-4(3H)-one
Packaging: 500mg
Price: $675
Updated: 2021/12/16

Alichem

Product number: 167158705
Product name: 6-Bromo-2-chloroquinazolin-4(3H)-one
Packaging: 5g
Price: $707.02
Updated: 2021/12/16

Alichem

Product number: 167158705
Product name: 6-Bromo-2-chloroquinazolin-4(3H)-one
Packaging: 10g
Price: $990
Updated: 2021/12/16

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6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE Chemical Properties,Usage,Production

Synthesis

102393-82-8

167158-70-5

Step C: Synthesis of 6-bromo-2-chloroquinazolin-4(3H)-one 6-Bromo-2,4-dichloroquinazoline (2.0 g, 7.20 mmol) was dissolved in THF (17.99 mL), 1N NaOH solution (17.99 mL, 17.99 mmol) was added, and the reaction was stirred for 2.5 h at room temperature. Upon completion of the reaction, the reaction solution was cooled to 0 °C and the pH was adjusted with AcOH to 5. The precipitated light yellow solid was collected by filtration and washed with water. The resulting solid was azeotropized by toluene (3×) to remove residual water to afford 6-bromo-2-chloroquinazolin-4(3H)-one (1.625 g, 87%). The product was analyzed by ES-LCMS: m/z 259.0, 261.0 [M+H]+.

References

[1] Patent: WO2012/87938, 2012, A1. Location in patent: Page/Page column 114
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 10, p. 2297 - 2300

6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE Suppliers

China 50 United Kingdom 1 United States 4 Global 55

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View Lastest Price from 6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE manufacturers

Career Henan Chemical Co

Product: 6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE 167158-70-5
Price: US $5.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-01-12

167158-70-5, 6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONERelated Search:

6-Bromoquinazolin-4-ol 6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE

6-BROMO-2-CHLOROQUINAZOLIN-4(1H)-ONE

6-bromo-2-chloroquinazolin-4(3H)-one

6-Bromo-2-chloro-4(3H)-quinazolinone

2-Chloro-6-broMoquinazolin-4(3H)-one

6-Bromo-2-chloroquinazolin-4(3H)

4(3H)-Quinazolinone, 6-bromo-2-chloro-

6-Bromo-2-chloroquinazolin-4-ol

6-bromo-2-chloro-3,4-dihydroquinazolin-4-one

167158-70-5

505084-69-3