ChemicalBook > CAS DataBase List > MECLOCYCLINE SULFOSALICYLATE SALT

MECLOCYCLINE SULFOSALICYLATE SALT

Product Name: MECLOCYCLINE SULFOSALICYLATE SALT
CAS No.: 73816-42-9
Chemical Name: MECLOCYCLINE SULFOSALICYLATE SALT
Synonyms: Meclan;Meclutin;Meclosorb;Mecloderm;Meclan Cream;Unii-46vza7rx2b;Einecs 277-614-2;5-Sulfosalicylate;MECLOCYLINESULFOSALICYLATE;FYSVKUUNXYGFLA-CCHMMTNSSA-N
CBNumber: CB6246958
Molecular Formula: C29H27ClN2O14S
Formula Weight: 695.05
MOL File: 73816-42-9.mol

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MECLOCYCLINE SULFOSALICYLATE SALT Property

Melting point:: >193°C (dec.)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: methanol: soluble10ML, clear, very dark yellow (200 mg + 10 mL MeOH)
form: Solid
color: yellow-green powder
Stability:: Hygroscopic

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Safety

WGK Germany: 3
HS Code: 2941300000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3200
Product name: Meclocycline Sulfosalicylate
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 500MG
Price: $392
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1377508
Product name: Meclocycline sulfosalicylate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 300mg
Price: $385
Updated: 2025/07/31

Sigma-Aldrich

Product number: M1388
Product name: Meclocycline sulfosalicylate salt
Packaging: 500mg
Price: $62.5
Updated: 2023/06/20

TRC

Product number: M202720
Product name: Meclocycline sulfosalicylate salt
Packaging: 100mg
Price: $185
Updated: 2021/12/16

Usbiological

Product number: 164837
Product name: Meclocycline Sulfosalicylate Salt
Packaging: 100mg
Price: $460
Updated: 2021/12/16

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MECLOCYCLINE SULFOSALICYLATE SALT Chemical Properties,Usage,Production

Uses

Antibacterial;Antibacterial

Uses

Meclocycline Sulfosalicylate Salt is a salt prepared from demeclocycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in solution with 2-hydroxy-3-carboxybenenesulphonic acid. Like all tetracyclines, meclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. The unusual complex counter-ion is likely to add an antiseptic component to the use of the compound for skin infections.

Uses

Meclocycline is a tetracycline antibiotic that is topically used for skin infections and irritations.

brand name

Meclan (Johnson & Johnson).

General Description

Meclocycline, 7-chloro-6-deoxy-6-demethyl-6-methylene-5-oxytetracycline sulfosalicylate (Meclan), is a semisyntheticderivative prepared from oxytetracycline.Although meclocycline has been used in Europe for manyyears, it became available only relatively recently in theUnited States for a single therapeutic indication, the treatmentof acne. It is available as the sulfosalicylate salt in a1% cream.
Meclocycline sulfosalicylate is a bright yellow, crystallinepowder that is slightly soluble in water and insolublein organic solvents. It is light sensitive and should be storedin light-resistant containers.

IC 50

Tetracycline

MECLOCYCLINE SULFOSALICYLATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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MECLOCYCLINE SULFOSALICYLATE SALT Suppliers

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73816-42-9, MECLOCYCLINE SULFOSALICYLATE SALTRelated Search:

1-(5-Chloro-2-hydroxyphenyl)ethanone 2-ALLYL-4-CHLOROPHENOL MECLOCYCLINE SULFOSALICYLATE SALT 4-Chloro-3-methylphenol 5-Sulfosalicylic acid dihydrate 1-ACETYL-1-CYCLOHEXENE 5,6,7,8-TETRAHYDRO-1-NAPHTHOL o-Cresolsulfonic acid FEMA 3377 1-Tetralone L-ISOLEUCINOL HCL 4-Chloro-3-ethylphenol 4-Vinyl-1-cyclohexene 2,4-DIMETHYL-3-CYCLOHEXENE-1-METHANOL (E,Z)-2,6-DODECADIEN-1-AL 5-Chlorosalicylaldehyde 3-METHYL-2-BUTENE-1-AMINE HCL 3-AMINO-5-HYDROXY-PENTEN-1

MECLOCYCLINE SULFOSALICYLATE SALT

MECLOCYLINESULFOSALICYLATE

2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4A,5,5A,6,11,12A-octahydro-3,5,10,12,12A-pentahydroxy-6-methylene-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-, mono(2-hydroxy-5-sulfobenzoate) (salt)

Benzoic acid, 2-hydroxy-5-sulfo-, compd. with (4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-7-chloro-4-(dimethylamino)-1,4,4A,5,5A,6,11,12A-octahydro-3,5,10,12,12A-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide (1:1)

Einecs 277-614-2

Meclan

Meclocycline 5-sulfosalicylate

Mecloderm

Meclosorb

Meclutin

Unii-46vza7rx2b

Meclocycline Sulfosalicylate (300 mg)

(4S,4aR,5S,12aS)-7-chloro-4-(diMethylaMino)-3,5,10,12,12a-pentahydroxy-6-Methylene-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxaMide 2-hydroxy-5-sulfobenzoate

meclocycline sulfosalicylate

Benzoic acid, 2-hydroxy-5-sulfo-, compd. with [4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha)]-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide (1:1)

5-Sulfosalicylate

FYSVKUUNXYGFLA-CCHMMTNSSA-N

Meclan Cream

Meclocycline Sulfosalicylate (1377508)

Bacterial,Inhibitor,Meclocycline sulfosalicylate salt,inhibit,Antibiotic

Meclocycline Sulfosalicylate (300 mg) (DISCONTINUED)

Meclocycline sulfosalicylate salt, 10 mM in DMSO

73816-42-9

C29H27ClN2O14S

C22H21ClN2O8C7H6O6S

BioChemical

Antibiotics

Antibiotics G-M

Antibiotics A to Z

1694 Pharmaceuticals&Personal Care Products

Antibacterial

Antibiotics

Antibiotics A to

Antibiotics G-MAntibiotics

Chemical Structure Class

Interferes with Protein SynthesisSpectrum of Activity

L - ZEPA

Mechanism of Action

NeatsAntibiotics

Tetracyclines