ChemicalBook > CAS DataBase List > MECLOCYCLINE SULFOSALICYLATE SALT

MECLOCYCLINE SULFOSALICYLATE SALT

Product Name
MECLOCYCLINE SULFOSALICYLATE SALT
CAS No.
73816-42-9
Chemical Name
MECLOCYCLINE SULFOSALICYLATE SALT
Synonyms
Meclan;Meclutin;Meclosorb;Mecloderm;Meclan Cream;Unii-46vza7rx2b;Einecs 277-614-2;5-Sulfosalicylate;MECLOCYLINESULFOSALICYLATE;FYSVKUUNXYGFLA-CCHMMTNSSA-N
CBNumber
CB6246958
Molecular Formula
C29H27ClN2O14S
Formula Weight
695.05
MOL File
73816-42-9.mol
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MECLOCYCLINE SULFOSALICYLATE SALT Property

Melting point:
>193°C (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
methanol: soluble10ML, clear, very dark yellow (200 mg + 10 mL MeOH)
form 
Solid
color 
yellow-green powder
Stability:
Hygroscopic
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Safety

WGK Germany 
3
HS Code 
2941300000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3200
Product name
Meclocycline Sulfosalicylate
Purity
pharmaceutical secondary standard, certified reference material
Packaging
500MG
Price
$365
Updated
2024/03/01
Sigma-Aldrich
Product number
1377508
Product name
Meclocycline sulfosalicylate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
300mg
Price
$412
Updated
2024/03/01
Sigma-Aldrich
Product number
M1388
Product name
Meclocycline sulfosalicylate salt
Packaging
500mg
Price
$62.5
Updated
2023/06/20
TRC
Product number
M202720
Product name
Meclocycline sulfosalicylate salt
Packaging
100mg
Price
$185
Updated
2021/12/16
Usbiological
Product number
164837
Product name
Meclocycline Sulfosalicylate Salt
Packaging
100mg
Price
$460
Updated
2021/12/16
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MECLOCYCLINE SULFOSALICYLATE SALT Chemical Properties,Usage,Production

Uses

Antibacterial;Antibacterial

Uses

Meclocycline Sulfosalicylate Salt is a salt prepared from demeclocycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in solution with 2-hydroxy-3-carboxybenenesulphonic acid. Like all tetracyclines, meclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. The unusual complex counter-ion is likely to add an antiseptic component to the use of the compound for skin infections.

Uses

Meclocycline is a tetracycline antibiotic that is topically used for skin infections and irritations.

brand name

Meclan (Johnson & Johnson).

General Description

Meclocycline, 7-chloro-6-deoxy-6-demethyl-6-methylene-5-oxytetracycline sulfosalicylate (Meclan), is a semisyntheticderivative prepared from oxytetracycline.Although meclocycline has been used in Europe for manyyears, it became available only relatively recently in theUnited States for a single therapeutic indication, the treatmentof acne. It is available as the sulfosalicylate salt in a1% cream.
Meclocycline sulfosalicylate is a bright yellow, crystallinepowder that is slightly soluble in water and insolublein organic solvents. It is light sensitive and should be storedin light-resistant containers.

MECLOCYCLINE SULFOSALICYLATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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MECLOCYCLINE SULFOSALICYLATE SALT Suppliers

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73816-42-9, MECLOCYCLINE SULFOSALICYLATE SALTRelated Search:

1-(5-Chloro-2-hydroxyphenyl)ethanone 2-ALLYL-4-CHLOROPHENOL MECLOCYCLINE SULFOSALICYLATE SALT 4-Chloro-3-methylphenol 5-Sulfosalicylic acid dihydrate 1-ACETYL-1-CYCLOHEXENE 5,6,7,8-TETRAHYDRO-1-NAPHTHOL o-Cresolsulfonic acid FEMA 3377 1-Tetralone L-ISOLEUCINOL HCL 4-Chloro-3-ethylphenol 4-Vinyl-1-cyclohexene 2,4-DIMETHYL-3-CYCLOHEXENE-1-METHANOL (E,Z)-2,6-DODECADIEN-1-AL 5-Chlorosalicylaldehyde 3-METHYL-2-BUTENE-1-AMINE HCL 3-AMINO-5-HYDROXY-PENTEN-1

  • MECLOCYCLINE SULFOSALICYLATE SALT
  • MECLOCYLINESULFOSALICYLATE
  • 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4A,5,5A,6,11,12A-octahydro-3,5,10,12,12A-pentahydroxy-6-methylene-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-, mono(2-hydroxy-5-sulfobenzoate) (salt)
  • Benzoic acid, 2-hydroxy-5-sulfo-, compd. with (4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-7-chloro-4-(dimethylamino)-1,4,4A,5,5A,6,11,12A-octahydro-3,5,10,12,12A-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide (1:1)
  • Einecs 277-614-2
  • Meclan
  • Meclocycline 5-sulfosalicylate
  • Mecloderm
  • Meclosorb
  • Meclutin
  • Unii-46vza7rx2b
  • Meclocycline Sulfosalicylate (300 mg)
  • (4S,4aR,5S,12aS)-7-chloro-4-(diMethylaMino)-3,5,10,12,12a-pentahydroxy-6-Methylene-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxaMide 2-hydroxy-5-sulfobenzoate
  • meclocycline sulfosalicylate
  • Benzoic acid, 2-hydroxy-5-sulfo-, compd. with [4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha)]-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide (1:1)
  • 5-Sulfosalicylate
  • FYSVKUUNXYGFLA-CCHMMTNSSA-N
  • Meclan Cream
  • Meclocycline Sulfosalicylate (1377508)
  • Bacterial,Inhibitor,Meclocycline sulfosalicylate salt,inhibit,Antibiotic
  • Meclocycline Sulfosalicylate (300 mg) (DISCONTINUED)
  • Meclocycline sulfosalicylate salt, 10 mM in DMSO
  • 73816-42-9
  • C29H27ClN2O14S
  • C22H21ClN2O8C7H6O6S
  • BioChemical
  • Antibiotics
  • Antibiotics G-M
  • Antibiotics A to Z
  • 1694 Pharmaceuticals&Personal Care Products
  • Antibacterial
  • Antibiotics
  • Antibiotics A to
  • Antibiotics G-MAntibiotics
  • Chemical Structure Class
  • Interferes with Protein SynthesisSpectrum of Activity
  • L - ZEPA
  • Mechanism of Action
  • NeatsAntibiotics
  • Tetracyclines