6-Bromo-3-chloropyrazin-2-amine
- Product Name
- 6-Bromo-3-chloropyrazin-2-amine
- CAS No.
- 1082843-72-8
- Chemical Name
- 6-Bromo-3-chloropyrazin-2-amine
- Synonyms
- 6-Bromo-3-chloro-2-pyrazinamine;6-Bromo-3-chloropyrazin-2-amine;2-Amino-3-chloro-6-bromopyrazine;2-Amino-6-bromo-3-chloropyrazine;2-Pyrazinamine, 6-bromo-3-chloro-;3-Chloro-6-bromopyrazin-2-ylamine
- CBNumber
- CB62471576
- Molecular Formula
- C4H3BrClN3
- Formula Weight
- 208.44
- MOL File
- 1082843-72-8.mol
6-Bromo-3-chloropyrazin-2-amine Property
- Boiling point:
- 288℃
- Density
- 1.960
- Flash point:
- 128℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 0.05±0.10(Predicted)
- Appearance
- Off-white to light yellow Solid
- InChI
- InChI=1S/C4H3BrClN3/c5-2-1-8-3(6)4(7)9-2/h1H,(H2,7,9)
- InChIKey
- LYMPGCBRUNBZJX-UHFFFAOYSA-N
- SMILES
- C1(N)=NC(Br)=CN=C1Cl
N-Bromosuccinimide Price
- Product number
- X8875
- Product name
- 6-Bromo-3-chloropyrazin-2-amine
- Packaging
- 250mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- 073737
- Product name
- 6-Bromo-3-chloropyrazin-2-amine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $240
- Updated
- 2021/12/16
- Product number
- HCH0367742
- Product name
- 6-BROMO-3-CHLOROPYRAZIN-2-AMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.15
- Updated
- 2021/12/16
- Product number
- A358442
- Product name
- 6-Bromo-3-chloropyrazin-2-amine
- Purity
- 97%
- Packaging
- 100mg
- Price
- $32
- Updated
- 2021/12/16
- Product number
- A358442
- Product name
- 6-Bromo-3-chloropyrazin-2-amine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
6-Bromo-3-chloropyrazin-2-amine Chemical Properties,Usage,Production
Synthesis
1082843-70-6
1082843-72-8
General procedure for the synthesis of 3-chloro-6-bromopyrazin-2-amine from 3,5-dibromo-2-chloropyrazine: 3,5-dibromo-2-chloropyrazine (50.0 g, 184 mmol) and concentrated ammonia (150 mL) were added to a 250 mL sealed tube. The reaction mixture was stirred at 100 °C overnight. Upon completion of the reaction, it was cooled to room temperature and the resulting solid product was collected by filtration. The resulting solid was dried under reduced pressure in an oven to afford 3-chloro-6-bromopyrazin-2-amine as a gray solid (28.0 g, 66% yield), which could be used in subsequent reactions without further purification.
References
[1] Patent: US2014/364414, 2014, A1. Location in patent: Paragraph 0945; 0954-0955
[2] Patent: US2009/286798, 2009, A1. Location in patent: Page/Page column 27
6-Bromo-3-chloropyrazin-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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