ChemicalBook > CAS DataBase List > PROTRIPTYLINE HYDROCHLORIDE

PROTRIPTYLINE HYDROCHLORIDE

Product Name
PROTRIPTYLINE HYDROCHLORIDE
CAS No.
1225-55-4
Chemical Name
PROTRIPTYLINE HYDROCHLORIDE
Synonyms
mk-240;maximed;concordin;normethylex4442;PROTRIPTYLINE HCL;Propriptyline HCl;Propriptyline HCl;triptilhydrochloride;Protirine hydrochloride;Protriptylin hydrochloride
CBNumber
CB6248396
Molecular Formula
C19H22ClN
Formula Weight
299.84
MOL File
1225-55-4.mol
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PROTRIPTYLINE HYDROCHLORIDE Property

Melting point:
169-171°
Flash point:
9℃
storage temp. 
2-8°C
solubility 
H2O: soluble50mg/mL
pka
8.2(at 25℃)
form 
powder
color 
white to off-white
Water Solubility 
H2O: 50mg/mL
Stability:
Hygroscopic
InChI
InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3;1H
InChIKey
OGQDIIKRQRZXJH-UHFFFAOYSA-N
SMILES
C1(CCCNC)C2C=CC=CC=2C=CC2C=CC=CC1=2.Cl
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Safety

Hazard Codes 
Xn,T,F
Risk Statements 
20/21/22-36/37/38-39/23/24/25-23/24/25-11
Safety Statements 
26-36-45-36/37-16-7
RIDADR 
3249
WGK Germany 
3
RTECS 
HP1400000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2921490002
Toxicity
dog,LDLo,oral,400mg/kg (400mg/kg),"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 88, 1972.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P-903
Product name
Protriptyline hydrochloride solution
Purity
1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1ML
Price
$99
Updated
2025/07/31
Sigma-Aldrich
Product number
1580002
Product name
Protriptyline hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$373
Updated
2025/07/31
Sigma-Aldrich
Product number
P8813
Product name
Protriptyline hydrochloride
Purity
≥99% (TLC), powder
Packaging
100mg
Price
$98.1
Updated
2023/01/07
Sigma-Aldrich
Product number
P8813
Product name
Protriptyline hydrochloride
Purity
≥99% (TLC), powder
Packaging
500mg
Price
$217
Updated
2023/01/07
ChemScene
Product number
CS-4422
Product name
Protriptyline hydrochloride
Purity
99.91%
Packaging
50mg
Price
$72
Updated
2021/12/16
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PROTRIPTYLINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Monoamine reuptake inhibitor; tricyclic antidepressant.

brand name

Vivactil (Odyssey).

General Description

Protriptyline hydrochloride, N-methyl-5H-dibenzo[a,d]-cycloheptene-5-propylamine hydrochloride, 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene hydrochloride(Vivactil), like the other compounds under consideration, isan effective antidepressant. The basis for its chemical namingcan be seen by consulting the naming and the structureof imipramine. Protriptyline is a structural isomer of nortriptyline.Inactivation can be expected to involve the relativelylocalized double bond. Because it is a monomethylcompound, its sedative potential is low.

Biochem/physiol Actions

Norepinephrine uptake blocker.

PROTRIPTYLINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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PROTRIPTYLINE HYDROCHLORIDE Suppliers

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1225-55-4, PROTRIPTYLINE HYDROCHLORIDERelated Search:

Plerixafor 8HCl (AMD3100 8HCl) Pramipexole Impurity 4 Propafenone Hydrochloride PROTRIPTYLINE HYDROCHLORIDE 5H-dibenzo[a,d]cycloheptene PROTRIPTYLINE

  • concordin
  • d)cyclohepten-5-propylamine,n-methyl-5h-dibenzo(hydrochloride
  • maximed
  • mk-240
  • n-methyl-5h-dibenzo(a,d)cycloheptene-5-propylaminehydrochloride
  • normethylex4442
  • triptilhydrochloride
  • Protriptylin hydrochloride
  • 5H-Dibenzo[A,D]cyclohepten-5-propylamine, N-methyl-, hydrochloride
  • 5H-Dibenzo[A,D]cycloheptene-5-propanamine, N-methyl-, hydrochloride
  • 5H-Dibenzo[A,D]cycloheptene-5-propylamine, N-methyl-, hydrochloride
  • Protriptyline HCl, 1.0 mg/mL
  • Protriptyline Hydrochloride (200 mg)
  • 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-Methylpropan-1-aMine hydrochloride
  • N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine hydrochloride
  • PROTRIPTYLINE HCL
  • PROTRIPTYLINE HYDROCHLORIDE
  • 5-(3-methylaminopropyl)-5h-dibenzo(a,d)cycloheptenehydrochloride
  • Protriptyline hydrochloride solution
  • Protriptyline Hydrochloride (1580002)
  • Cholinesterase (ChE),Aβ Self-Assembly,Protriptyline,AChE,Protriptyline hydrochloride,alzheimers,Inhibitor,inhibit
  • Protirine hydrochloride
  • Protriptyline hydrochloride in methanol
  • Protriptyline hydrochloride, 10 mM in DMSO
  • Protriptyline.HCl, 1mg/ml in Methanol (as free base)
  • Protriptyline Hydrochloride 1.0 mg/ml in Methanol (as free base)
  • Propriptyline HCl
  • Propriptyline HCl
  • 1225-55-4
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