Uses
ChemicalBook > CAS DataBase List > 3,5-Dichloropyrazine-2-carbonitrile

3,5-Dichloropyrazine-2-carbonitrile

Uses
Product Name
3,5-Dichloropyrazine-2-carbonitrile
CAS No.
313339-92-3
Chemical Name
3,5-Dichloropyrazine-2-carbonitrile
Synonyms
3,5-Dichloropyrazinecarbonitrile;3,5-Dichloro-2-pyrazinecarbonitrile;5-dichloropyrazine-2-carbonitrile;1,3-Propanediol,1-(5-piperidinyl)-;3,5-Dichloropyrazine-2-carbonitrile;2-Pyrazinecarbonitrile, 3,5-dichloro-;3,5-Dichloropyrazine-2-carbonitrile ISO 9001：2015 REACH;2-Cyano-3,5-dichloropyrazine, 2-Cyano-3,5-dichloro-1,4-diazin;2-Cyano-3,5-dichloropyrazine, 2-Cyano-3,5-dichloro-1,4-diazine
CBNumber
CB62489661
Molecular Formula
C5HCl2N3
Formula Weight
173.99
MOL File
313339-92-3.mol
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3,5-Dichloropyrazine-2-carbonitrile Property

Boiling point:
277℃
Density 
1.60
Flash point:
121℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-8.85±0.10(Predicted)
form 
solid
color 
White
InChI
InChI=1S/C5HCl2N3/c6-4-2-9-3(1-8)5(7)10-4/h2H
InChIKey
SDTCGHLDTSGIRR-UHFFFAOYSA-N
SMILES
C1(C#N)=NC=C(Cl)N=C1Cl
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D437140
Product name
3,5-Dichloropyrazine-2-carbonitrile
Packaging
250mg
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
073768
Product name
3,5-Dichloropyrazine-2-carbonitrile
Purity
95+%
Packaging
1g
Price
$69
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
D13904
Product name
3,5-Dichloropyrazine-2-carbonitrile
Packaging
1g
Price
$15
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD138213
Product name
3,5-Dichloropyrazine-2-carbonitrile
Packaging
1g
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD138213
Product name
3,5-Dichloropyrazine-2-carbonitrile
Packaging
2g
Price
$120
Updated
2021/12/16
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3,5-Dichloropyrazine-2-carbonitrile Chemical Properties,Usage,Production

Uses

3,5-Dichloropyrazine-2-carboxynitrile is a chemical intermediate.

Synthesis

312736-50-8

313339-92-3

General procedure for the synthesis of 3,5-dichloropyrazine-2-carbonitrile from 3,5-dichloropyrazine-2-carboxamide: To a solution of acetonitrile (100 mL) of 3,5-dichloropyrazine-2-carboxamide (5.0 g, 13.3 mmol) obtained in Preparation Example 13.1 was added phosphorous triclorethylene (6.76 mL, 72.3 mmol), and the reaction was stirred for 4 hr at 80 °C. Upon completion of the reaction, the reaction mixture was diluted with water and subsequently extracted with ethyl acetate and the organic layer was washed with saturated saline. The organic layer was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography (eluent: 20% n-hexane/ethyl acetate) to afford 3,5-dichloropyrazine-2-carbonitrile (2.94 g, 65% yield) as a solid.

References

[1] Organic Letters, 2013, vol. 15, # 9, p. 2156 - 2159
[2] Patent: WO2016/6975, 2016, A2. Location in patent: Paragraph 461-463
[3] Patent: KR2016/7347, 2016, A. Location in patent: Paragraph 0359; 0363; 0364; 0365
[4] Patent: WO2018/22992, 2018, A1. Location in patent: Paragraph 0725; 0726
[5] Patent: US2018/72743, 2018, A1. Location in patent: Paragraph 1330-1331

3,5-Dichloropyrazine-2-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-Dichloropyrazine-2-carbonitrile Suppliers

China 111 India 2 United Kingdom 2 United States 9 Global 124
A.J Chemicals
Tel
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Fax
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Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
Gagri Global IT Services Pvt. Ltd.
Tel
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Fax
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Email
info@sapalaorganics.com
Country
India
ProdList
1321
Advantage
58
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View Lastest Price from 3,5-Dichloropyrazine-2-carbonitrile manufacturers

Henan Fengda Chemical Co., Ltd
Product
3,5-Dichloropyrazine-2-carbonitrile 313339-92-3
Price
US $10.00-3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-26
Career Henan Chemical Co
Product
3,5-Dichloropyrazine-2-carbonitrile 313339-92-3
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-11

313339-92-3, 3,5-Dichloropyrazine-2-carbonitrileRelated Search:


  • 5-dichloropyrazine-2-carbonitrile
  • 3,5-Dichloro-2-pyrazinecarbonitrile
  • 3,5-Dichloropyrazinecarbonitrile
  • 3,5-Dichloropyrazine-2-carbonitrile
  • 2-Cyano-3,5-dichloropyrazine, 2-Cyano-3,5-dichloro-1,4-diazine
  • 2-Cyano-3,5-dichloropyrazine, 2-Cyano-3,5-dichloro-1,4-diazin
  • 2-Pyrazinecarbonitrile, 3,5-dichloro-
  • 3,5-Dichloropyrazine-2-carbonitrile ISO 9001：2015 REACH
  • 1,3-Propanediol,1-(5-piperidinyl)-
  • 313339-92-3