ChemicalBook > CAS DataBase List > 5,7-difluorochroman-4-one

5,7-difluorochroman-4-one

Product Name
5,7-difluorochroman-4-one
CAS No.
844648-22-2
Chemical Name
5,7-difluorochroman-4-one
Synonyms
Tegoprazan Impurity 10;5,7-difluorochroman-4-one;Tigola produces impurity 10;5,7-difluoro-2,3-dihydrochromen-4-one;5,7-Difluoro-3,4-dihydro-4H-chromen-4-one;5,7-Difluoro-2,3-dihydro-4H-chromen-4-one;5,7-DIFLUORO-2,3-DIHYDRO-1-BENZOPYRAN-4-ONE;5,7-Difluoro-2,3-dihydro-4H-1-benzopyran-4-one;5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5,7-difluoro-2,3-dihydro-
CBNumber
CB62489782
Molecular Formula
C9H6F2O2
Formula Weight
184.14
MOL File
844648-22-2.mol
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5,7-difluorochroman-4-one Property

Boiling point:
283℃
Density 
1.392
Flash point:
121℃
storage temp. 
Sealed in dry,Room Temperature
Appearance
White to light yellow Solid
InChI
InChI=1S/C9H6F2O2/c10-5-3-6(11)9-7(12)1-2-13-8(9)4-5/h3-4H,1-2H2
InChIKey
OJVRCPGUGZXUAP-UHFFFAOYSA-N
SMILES
C1OC2=CC(F)=CC(F)=C2C(=O)C1
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Safety

HS Code 
2932990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific
Product number
PC201320
Product name
5,7-Difluorochroman-4-one
Purity
95%
Packaging
250mg
Price
$90
Updated
2021/12/16
AK Scientific
Product number
J55733
Product name
5,7-Difluorochroman-4-one
Packaging
250mg
Price
$95
Updated
2021/12/16
Apolloscientific
Product number
PC201320
Product name
5,7-Difluorochroman-4-one
Purity
95%
Packaging
1g
Price
$225
Updated
2021/12/16
AK Scientific
Product number
J55733
Product name
5,7-Difluorochroman-4-one
Packaging
1g
Price
$238
Updated
2021/12/16
SynQuest Laboratories
Product number
2H17-3-0B
Product name
5,7-Difluorochroman-4-one
Purity
95%
Packaging
1g
Price
$360
Updated
2021/12/16
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5,7-difluorochroman-4-one Chemical Properties,Usage,Production

Uses

5,7-Difluorochroman-4-one is used as a reagent in the prepaation of tetrazolinone compounds,used as pest control agents.

Synthesis

844648-19-7

844648-22-2

At 50 °C, 3-(3,5-difluorophenoxy)propionic acid (20.0 g, 99 mmol) was added to 60 mL of concentrated sulfuric acid in batches and stirred until completely dissolved. The resulting yellow-green solution was stirred continuously at 50 °C for 1.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and slowly poured into 800 mL of ice water. After standing for 1 hour, the colorless precipitate was collected by filtration and washed well with cold water. The resulting 5,7-difluorobenzodihydropyran-4-one was dried over phosphorus pentoxide to give 15.69 g of colorless solid in 86% yield.

References

[1] Patent: WO2008/151927, 2008, A2. Location in patent: Page/Page column 61
[2] Patent: KR2018/11830, 2018, A. Location in patent: Paragraph 0061; 0076; 0077
[3] Patent: US2005/38032, 2005, A1. Location in patent: Page/Page column 31

5,7-difluorochroman-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

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5,7-difluorochroman-4-one Suppliers

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View Lastest Price from 5,7-difluorochroman-4-one manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
5,7-difluorochroman-4-one 844648-22-2
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%min
Supply Ability
100kg
Release date
2025-06-12

844648-22-2, 5,7-difluorochroman-4-oneRelated Search:

Dimethoxymethane 1-benzyl-2-methyl-1H-imidazole-carbaldehyde 1H-Benzimidazole-6-carboxylic acid, 4-hydroxy-2-methyl-1-(phenylmethyl)-, ethyl ester (Dimethylamino)acetaldehyde Dimethyl Acetal 2-Aminobiphenyl 1-(piperidine-4-carbonyl)piperidine-4-carboxylic acid hydrochloride Butanedioic acid, 2-[[2-methyl-1-(phenylmethyl)-1H-imidazol-5-yl]methylene]-, 1-ethyl ester, (2E)- 1H-Benzimidazole-6-carboxamide, 4-hydroxy-N,N,2-trimethyl-1-(phenylmethyl)- Benzoic acid, 4-[[4-(aminocarbonyl)-1-piperidinyl]methyl]- Revefenacin Impurity 16 (R)-5,7-difluorochroman-4-ol 1-benzyl-4-hydroxy-2-methyl-1H-benzo[d]imidazole-6-carboxylic acid

  • 4H-1-Benzopyran-4-one, 5,7-difluoro-2,3-dihydro-
  • 5,7-Difluoro-2,3-dihydro-4H-chromen-4-one
  • 5,7-Difluoro-3,4-dihydro-4H-chromen-4-one
  • 5,7-difluorochroman-4-one
  • 5,7-DIFLUORO-2,3-DIHYDRO-1-BENZOPYRAN-4-ONE
  • 5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-one
  • Tegoprazan Impurity 10
  • Tigola produces impurity 10
  • 5,7-difluoro-2,3-dihydrochromen-4-one
  • methyl (S)-2-amino-3-(3-iodo-4-methoxyphenyl)propanoate
  • 5,7-Difluoro-2,3-dihydro-4H-1-benzopyran-4-one
  • 844648-22-2