Incyclinide

Product Name: Incyclinide
CAS No.: 15866-90-7
Chemical Name: Incyclinide
Synonyms: COL 3;CMT 3;Metastat;NSC 683551;Incyclinide;Incyclinide (CMT-3);Incyclinide, 10 mM in DMSO;INCYCLINIDE (CMT-3, COL-3);COL 3,CMT 3,Matrix metalloproteinases,inhibit,Inhibitor,Incyclinide,CMT3,COL3,MMP;(4aS,5aR,12aS)-3,10,12,12a-Tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
CBNumber: CB62498809
Molecular Formula: C19H17NO7
Formula Weight: 371.34
MOL File: 15866-90-7.mol

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Incyclinide Property

Melting point:: 228-231 °C
Boiling point:: 752.8±60.0 °C(Predicted)
Density: 1.70±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:100.0(Max Conc. mg/mL);269.29(Max Conc. mM)
form: A solid
pka: 4.50±1.00(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 34597
Product name: Incyclinide
Purity: ≥98%
Packaging: 1mg
Price: $69
Updated: 2026/04/30

Cayman Chemical

Product number: 34597
Product name: Incyclinide
Purity: ≥98%
Packaging: 5mg
Price: $214
Updated: 2026/04/30

Cayman Chemical

Product number: 34597
Product name: Incyclinide
Purity: ≥98%
Packaging: 10mg
Price: $329
Updated: 2026/04/30

Usbiological

Product number: 354898
Product name: COL3
Packaging: 48Tests
Price: $588
Updated: 2021/12/16

Usbiological

Product number: 354897
Product name: COL3
Packaging: 48Tests
Price: $588
Updated: 2021/12/16

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Incyclinide Chemical Properties,Usage,Production

Uses

Treatment of acne, rosacea, and acute respiratory distress syndrome.

Uses

Incyclinide is MMP inhibitor. Potential anti-COVID-19 drugs which which significantly downregulate ACE2 activity.

brand name

Metastat (CollaGenex).

in vivo

Incyclinide inhibits tooth movement in the rat, probably by reducing the number of osteoclasts at the compression side. This might be due to induction of apoptosis in activated osteoclasts or reduced osteoclast migration. Reduced MMP activity by incyclinide might also directly inhibit degradation of the organic bone matrix^[3].

Incyclinide Preparation Products And Raw materials

Raw materials

Preparation Products

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Incyclinide Suppliers

CHINA 38 United States 6 Global 44

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
Advantage: 55

Shanghai Fuhe Chemistry Technology Co., Ltd.

Tel: 0086-21-67651709
Fax: 0086-21-67651705
Email: cfx759@hotmail.com
Country: China
ProdList: 410
Advantage: 57

MedChemexpress LLC

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Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
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Shanghai EFE Biological Technology Co., Ltd.

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Country: China
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Shanghai YuanYe Biotechnology Co., Ltd.

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Dezhou LonWel Pharmaceutical Technology Co., Ltd.

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Country: China
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Zhengzhou Alfa Chemical Co.,Ltd

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Email: sale04@alfachem.cn
Country: China
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TargetMol Chemicals Inc.

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InvivoChem

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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15866-90-7, IncyclinideRelated Search:

INCYCLINIDE (CMT-3, COL-3)

Incyclinide

2-NaphthacenecarboxaMide,1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-,(4aS,5aR,12aS)-

CMT 3

COL 3

Metastat

NSC 683551

Incyclinide (CMT-3)

COL 3,CMT 3,Matrix metalloproteinases,inhibit,Inhibitor,Incyclinide,CMT3,COL3,MMP

(4aS,5aR,12aS)-3,10,12,12a-Tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

Incyclinide, 10 mM in DMSO

(4AS,5AR,12AS)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-2-NAPHTHACENECARBOXAMIDE

15866-90-7