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Incyclinide

Product Name
Incyclinide
CAS No.
15866-90-7
Chemical Name
Incyclinide
Synonyms
COL 3;CMT 3;Metastat;NSC 683551;Incyclinide;Incyclinide (CMT-3);Incyclinide, 10 mM in DMSO;INCYCLINIDE (CMT-3, COL-3);COL 3,CMT 3,Matrix metalloproteinases,inhibit,Inhibitor,Incyclinide,CMT3,COL3,MMP;(4aS,5aR,12aS)-3,10,12,12a-Tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
CBNumber
CB62498809
Molecular Formula
C19H17NO7
Formula Weight
371.34
MOL File
15866-90-7.mol
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Incyclinide Property

Melting point:
228-231 °C
Boiling point:
752.8±60.0 °C(Predicted)
Density 
1.70±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:100.0(Max Conc. mg/mL);269.29(Max Conc. mM)
form 
A solid
pka
4.50±1.00(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
354898
Product name
COL3
Packaging
48Tests
Price
$588
Updated
2021/12/16
Usbiological
Product number
354897
Product name
COL3
Packaging
48Tests
Price
$588
Updated
2021/12/16
ChemScene
Product number
CS-7504
Product name
Incyclinide
Purity
95.70%
Packaging
50mg
Price
$950
Updated
2021/12/16
ChemScene
Product number
CS-7504
Product name
Incyclinide
Purity
95.70%
Packaging
1mg
Price
$100
Updated
2021/12/16
ChemScene
Product number
CS-7504
Product name
Incyclinide
Purity
95.70%
Packaging
5mg
Price
$150
Updated
2021/12/16
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Incyclinide Chemical Properties,Usage,Production

Uses

Treatment of acne, rosacea, and acute respiratory distress syndrome.

Uses

Incyclinide is MMP inhibitor. Potential anti-COVID-19 drugs which which significantly downregulate ACE2 activity.

brand name

Metastat (CollaGenex).

in vivo

Incyclinide inhibits tooth movement in the rat, probably by reducing the number of osteoclasts at the compression side. This might be due to induction of apoptosis in activated osteoclasts or reduced osteoclast migration. Reduced MMP activity by incyclinide might also directly inhibit degradation of the organic bone matrix[3].

Incyclinide Preparation Products And Raw materials

Raw materials

Preparation Products

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Incyclinide Suppliers

CHINA 33 United States 6 Global 39
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
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58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
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58
Cayman Chemical Company
Tel
--
Fax
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Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
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58

15866-90-7, IncyclinideRelated Search:


  • INCYCLINIDE (CMT-3, COL-3)
  • Incyclinide
  • 2-NaphthacenecarboxaMide,1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-,(4aS,5aR,12aS)-
  • CMT 3
  • COL 3
  • Metastat
  • NSC 683551
  • Incyclinide (CMT-3)
  • COL 3,CMT 3,Matrix metalloproteinases,inhibit,Inhibitor,Incyclinide,CMT3,COL3,MMP
  • (4aS,5aR,12aS)-3,10,12,12a-Tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
  • Incyclinide, 10 mM in DMSO
  • (4AS,5AR,12AS)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-2-NAPHTHACENECARBOXAMIDE
  • 15866-90-7