4-(2-CHLOROACETYL)MORPHOLINE

Product Name: 4-(2-CHLOROACETYL)MORPHOLINE
CAS No.: 1440-61-5
Chemical Name: 4-(2-CHLOROACETYL)MORPHOLINE
Synonyms: NSC 54542;BUTTPARK 30\04-53;AKOS BBS-00000944;TIMTEC-BB SBB005580;LABOTEST-BB LT00000129;N-(CHLOROACETYL)MORPHOLINE;4-(chloroacetyl)-morpholin;chloroaceticacidmorpholide;4-(CHLOROACETYL)MORPHOLINE;4-(2-CHLOROACETYL)MORPHOLINE
CBNumber: CB6250656
Molecular Formula: C6H10ClNO2
Formula Weight: 163.6
MOL File: 1440-61-5.mol

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4-(2-CHLOROACETYL)MORPHOLINE Property

Melting point:: 26-30 °C
Boiling point:: 152-160 °C(Press: 6 Torr)
Density: 1.257 g/mL at 25 °C
refractive index: n20/D 1.512
Flash point:: 110 °C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: -1.26±0.20(Predicted)
form: Solid
color: Colourless to Pale Yellow Oil
Stability:: Hygroscopic
CAS DataBase Reference: 1440-61-5(CAS DataBase Reference)
EPA Substance Registry System: Morpholine, 4-(chloroacetyl)- (1440-61-5)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39
RIDADR: UN3261
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 8
PackingGroup: III
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H319Causes serious eye irritation

Precautionary statements

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C2588
Product name: 2-Chloro-1-morpholinoethan-1-one
Purity: min. 98.0 %
Packaging: 5G
Price: $54
Updated: 2025/07/31

TCI Chemical

Product number: C2588
Product name: 2-Chloro-1-morpholinoethan-1-one
Purity: min. 98.0 %
Packaging: 25G
Price: $162
Updated: 2025/07/31

TRC

Product number: C363700
Product name: 4-(Chloroacetyl)morpholine
Packaging: 10g
Price: $875
Updated: 2021/12/16

Oakwood

Product number: 005874
Product name: N-(Chloroacetyl)morpholine
Purity: 98%
Packaging: 1g
Price: $10
Updated: 2021/12/16

Oakwood

Product number: 005874
Product name: N-(Chloroacetyl)morpholine
Purity: 98%
Packaging: 5g
Price: $12
Updated: 2021/12/16

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4-(2-CHLOROACETYL)MORPHOLINE Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Uses

The chloroacetyl derivatives are microbicides for adhesives, cellulose foams, oil emulsions, cooling water, etc.

Synthesis

110-91-8

79-04-9

1440-61-5

Step 1: Morpholine (1.00 mL, 11.5 mmol) and toluene (30 mL) were added to a dry three-necked flask equipped with a magnetic stirrer under nitrogen protection. Potassium carbonate (3.17 g, 22.9 mmol) was then added and stirred until completely dissolved. Chloroacetyl chloride (0.91 mL, 11.4 mmol) was slowly added dropwise under the cooling of an ice bath, and after completion of the dropwise addition, the ice bath was removed, the temperature was raised to 60 °C and the reaction was continuously stirred for 2 hours. After completion of the reaction, the reaction mixture was cooled to room temperature, filtered to remove insoluble solids, and the solids were washed with a small amount of toluene. The filtrate and washings were combined and concentrated under reduced pressure to remove the solvent to give N-chloroacetylmorpholine as a white solid (1.87 g, quantitative yield). The product was characterized by 1H-NMR (270 MHz, CDCl3): δ 3.51-3.54 (m, 2H), 3.62-3.65 (m, 2H), 3.68-3.74 (m, 4H), 4.07 (s, 2H).

References

[1] Patent: EP1650194, 2006, A1. Location in patent: Page/Page column 34
[2] Patent: WO2012/72019, 2012, A1. Location in patent: Page/Page column 71-72
[3] Molecules, 2015, vol. 20, # 11, p. 19984 - 20013
[4] Patent: WO2016/147144, 2016, A1. Location in patent: Page/Page column 222
[5] Journal of Medicinal Chemistry, 2009, vol. 52, # 21, p. 6660 - 6671

4-(2-CHLOROACETYL)MORPHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-CHLOROACETYL)MORPHOLINE Suppliers

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View Lastest Price from 4-(2-CHLOROACETYL)MORPHOLINE manufacturers

Career Henan Chemical Co

Product: 4-(2-CHLOROACETYL)MORPHOLINE 1440-61-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-08

1440-61-5, 4-(2-CHLOROACETYL)MORPHOLINERelated Search:

TIMTEC-BB SBB010861 4-(CHLOROACETYL)-2-METHYLMORPHOLINE 4-(2-chloropropanoyl)-2-methylmorpholine 4-(2-CHLOROACETYL)MORPHOLINE 4-[CHLORO(PHENYL)ACETYL]MORPHOLINE

2-Chloro-1-(morpholin-4-yl)ethan-1-one

4-(2-Chloroacetyl)morpholine 98%

2-Chloro-1-morpholinoethan-1-one, 95+%

2-CHLORO-1-MORPHOLIN-4-YL-ETHANONE >98%

4-(CHLOROACETYL)MORPHOLINE, 97+%

2-Chloro-1-(4-morpholinyl)ethanone, 2-Chloro-1-morpholinoethanone, 2-Morpholino-2-oxoethyl chloride, 4-Morpholinylcarbonylmethyl chloride, N-(Chloroacetyl)morpholine, Chloroacetic acid morpholide, Chloroacetic acid morpholine amide, Morpholine chloroacetamide

1-Morpholino-2-chloroethanone

2-Chloro-1-(4-Morpholinyl)ehanone

2-Chloro-1-Morpholino-1-ethanone

2-Chloro-1-Morpholinoethanone

4-Morpholinylcarbonylmethyl chloride

Chloroacetic acid morpholine amide

NSC 54542

2-Morpholino-2-oxoethyl chloride

MORPHOLINE, 4-(2-CHLOROACETYL)-

N-(CHLOROACETYL)MORPHOLINE

TIMTEC-BB SBB005580

4-(chloroacetyl)-morpholin

chloroaceticacidmorpholide

LABOTEST-BB LT00000129

BUTTPARK 30\04-53

AKOS BBS-00000944

4-(2-CHLOROACETYL)MORPHOLINE

4-(CHLOROACETYL)MORPHOLINE

2-CHLORO-1-MORPHOLIN-4-YL-ETHANONE

2-CHLORO-1-MORPHOLINOETHAN-1-ONE

2-CHLORO-1-(4-MORPHOLINYL)-1-ETHANONE

4-(2-Chloroacetyl)morpholine, 97+%

Morpholine, 4-(chloroacetyl)- (6CI,7CI,8CI,9CI)

Ethanone, 2-chloro-1-(4-morpholinyl)-

2-chloromorpholinoehtan-1-one

2-Chloro-1-morpholin-4-yl-ethanon

TIANFU CHEM----4-(2-CHLOROACETYL)MORPHOLINE

2-Chloro-1-(4-morpholinyl)ethanone

1440-61-5

C6H10ClNO2

KETONE

ACETYLHALIDE

Heterocycles

MTS & Sulfhydryl Active Reagents