6-Trifluoromethylpyridazin-3(2H)-one

Product Name: 6-Trifluoromethylpyridazin-3(2H)-one
CAS No.: 174607-36-4
Chemical Name: 6-Trifluoromethylpyridazin-3(2H)-one
Synonyms: 6-Trifluoromethyl-pyridazin-3-ol;6-Trifluoromethylpyridazin-3(2H)-one;6-(Trifluoromethyl)pyridazin-3(2h)-on;3-(trifluoromethyl)-1H-pyridazin-6-one;3(2H)-Pyridazinone, 6-(trifluoromethyl)-;6-(trifluoroMethyl)-2,3-dihydropyridazin-3-one
CBNumber: CB62518228
Molecular Formula: C5H3F3N2O
Formula Weight: 164.09
MOL File: 174607-36-4.mol

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6-Trifluoromethylpyridazin-3(2H)-one Property

Melting point:: 80-81 °C
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 10.05±0.40(Predicted)
Appearance: White to light yellow Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: T898898
Product name: 6-(Trifluoromethyl)pyridazin-3(2H)-one
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: PC904495
Product name: 6-(Trifluoromethyl)pyridazin-3(2H)-one
Purity: 95%
Packaging: 100mg
Price: $110
Updated: 2021/12/16

Apolloscientific

Product number: PC904495
Product name: 6-(Trifluoromethyl)pyridazin-3(2H)-one
Purity: 95%
Packaging: 250mg
Price: $175
Updated: 2021/12/16

ChemScene

Product number: CS-W019009
Product name: 6-(Trifluoromethyl)pyridazin-3(2H)-one
Packaging: 1g
Price: $215
Updated: 2021/12/16

Apolloscientific

Product number: PC904495
Product name: 6-(Trifluoromethyl)pyridazin-3(2H)-one
Purity: 95%
Packaging: 1g
Price: $445
Updated: 2021/12/16

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6-Trifluoromethylpyridazin-3(2H)-one Chemical Properties,Usage,Production

Synthesis

628332-15-0

174607-36-4

General procedure for the synthesis of 6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one from 6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one: a mixture of 6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one (90.0 g), bromine (30.5 mL), and acetic acid (270 mL) were stirred and reacted for 1 hour at 80 °C. Upon completion of the reaction, ice water (500 mL) was added to the reaction mixture to quench the reaction. The precipitated crystals were collected by filtration, washed sequentially with aqueous sodium bicarbonate and distilled water, and dried to give 6-(trifluoromethyl)pyridazin-3(2H)-one (58.74 g, 66% yield) as white crystals. The melting point of the product was 129-130 °C. 1H-NMR (CDCl3) δ: 7.14 (1H, dd, J = 9.9, 0.5 Hz), 7.54 (1H, d, J = 10.0 Hz), 12.64 (1H, brs).

References

[1] Tetrahedron, 2009, vol. 65, # 21, p. 4212 - 4219
[2] Patent: WO2003/99793, 2003, A1. Location in patent: Page 272
[3] Patent: US2011/34450, 2011, A1. Location in patent: Page/Page column 103
[4] Patent: WO2005/47279, 2005, A1. Location in patent: Page/Page column 48-49

6-Trifluoromethylpyridazin-3(2H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Trifluoromethylpyridazin-3(2H)-one Suppliers

China 70 India 1 United States 4 Global 75

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
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Country: China
ProdList: 5000
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Adamas Reagent, Ltd.

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Bide Pharmatech Ltd.

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Email: product02@bidepharm.com
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Shanghai Tombiopharma Chemical Co. Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Changzhou Hopschain Chemical Co.,Ltd.

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Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
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Country: China
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Amadis Chemical Company Limited

Tel: 571-89925085
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Country: China
ProdList: 131957
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View Lastest Price from 6-Trifluoromethylpyridazin-3(2H)-one manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 6-(Trifluoromethyl)pyridazin-3(2H)-one 174607-36-4
Price: US $1.60-9.60/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-20

Shanghai Rlavie Technology Co ltd

Product: 6-(trifluoromethyl)-2,3-dihydropyridazin-3-one 174607-36-4
Price: US $0.00/kg
Min. Order: 0.0001kg
Purity: 98%minHPLC
Supply Ability: 25kgs/month
Release date: 2022-06-07

Career Henan Chemical Co

Product: 6-Trifluoromethylpyridazin-3(2H)-one 174607-36-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%
Supply Ability: 200KG
Release date: 2018-08-15

174607-36-4, 6-Trifluoromethylpyridazin-3(2H)-oneRelated Search:

6-Trifluoromethylpyridazin-3(2H)-one

6-(Trifluoromethyl)pyridazin-3(2h)-on

6-(trifluoroMethyl)-2,3-dihydropyridazin-3-one

6-Trifluoromethyl-pyridazin-3-ol

3(2H)-Pyridazinone, 6-(trifluoromethyl)-

3-(trifluoromethyl)-1H-pyridazin-6-one

174607-36-4