ChemicalBook > CAS DataBase List > 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

Product Name
4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione
CAS No.
1104546-89-5
Chemical Name
4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione
Synonyms
RT-017290;BYK 204165;PARP Inhibitor XIV;BYK204165 >=98% (HPLC);4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione;4-(1-Methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinoline-1,3-dione;4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione;4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione;1,3(2H,4H)-Isoquinolinedione, 4-[(1-methyl-1H-pyrrol-2-yl)methylene]-;BYK-204165,poly ADP ribose polymerase,Inhibitor,PARP,antitumor,inhibit,BYK204165,BYK 204165
CBNumber
CB62518783
Molecular Formula
C15H12N2O2
Formula Weight
252.27
MOL File
1104546-89-5.mol
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4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Property

Boiling point:
492.5±45.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >20mg/mL
pka
9.30±0.20(Predicted)
form 
powder
color 
yellow
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Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B3188
Product name
BYK204165
Purity
≥98% (HPLC)
Packaging
5mg
Price
$158
Updated
2024/03/01
Sigma-Aldrich
Product number
B3188
Product name
BYK204165
Purity
≥98% (HPLC)
Packaging
25mg
Price
$493
Updated
2024/03/01
Cayman Chemical
Product number
21430
Product name
BYK204165
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
21430
Product name
BYK204165
Purity
≥98%
Packaging
5mg
Price
$142
Updated
2024/03/01
Sigma-Aldrich
Product number
528824
Product name
PARP Inhibitor XIV - CAS 1104546-89-5 - Calbiochem
Packaging
10mg
Price
$345
Updated
2024/03/01
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4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Chemical Properties,Usage,Production

Uses

BYK 204165 is an inhibitor of the poly(ADP-?ribose) polymerase (PARP), and it is 100-fold more selective for PARP-1.

Biochem/physiol Actions

BYK204165 is a potent and selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1). It is 100-fold selective for PARP-1 over PARP-2.

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Suppliers

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1104546-89-5, 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedioneRelated Search:


  • 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione
  • BYK 204165
  • 4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione
  • PARP Inhibitor XIV
  • 4-(1-Methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinoline-1,3-dione
  • RT-017290
  • 1,3(2H,4H)-Isoquinolinedione, 4-[(1-methyl-1H-pyrrol-2-yl)methylene]-
  • BYK204165 >=98% (HPLC)
  • 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione
  • BYK-204165,poly ADP ribose polymerase,Inhibitor,PARP,antitumor,inhibit,BYK204165,BYK 204165
  • 1104546-89-5