4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

Product Name: 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione
CAS No.: 1104546-89-5
Chemical Name: 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione
Synonyms: RT-017290;BYK 204165;PARP Inhibitor XIV;BYK204165 >=98% (HPLC);4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione;4-(1-Methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinoline-1,3-dione;4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione;4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione;1,3(2H,4H)-Isoquinolinedione, 4-[(1-methyl-1H-pyrrol-2-yl)methylene]-;BYK-204165,poly ADP ribose polymerase,Inhibitor,PARP,antitumor,inhibit,BYK204165,BYK 204165
CBNumber: CB62518783
Molecular Formula: C15H12N2O2
Formula Weight: 252.27
MOL File: 1104546-89-5.mol

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4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Property

Boiling point:: 492.5±45.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: >20mg/mL
pka: 9.30±0.20(Predicted)
form: powder
color: yellow

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Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H317May cause an allergic skin reaction
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B3188
Product name: BYK204165
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $158
Updated: 2024/03/01

Sigma-Aldrich

Product number: B3188
Product name: BYK204165
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $493
Updated: 2024/03/01

Cayman Chemical

Product number: 21430
Product name: BYK204165
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 21430
Product name: BYK204165
Purity: ≥98%
Packaging: 5mg
Price: $142
Updated: 2024/03/01

Sigma-Aldrich

Product number: 528824
Product name: PARP Inhibitor XIV - CAS 1104546-89-5 - Calbiochem
Packaging: 10mg
Price: $345
Updated: 2024/03/01

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4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Chemical Properties,Usage,Production

Uses

BYK 204165 is an inhibitor of the poly(ADP-?ribose) polymerase (PARP), and it is 100-fold more selective for PARP-1.

Biochem/physiol Actions

BYK204165 is a potent and selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1). It is 100-fold selective for PARP-1 over PARP-2.

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione Suppliers

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1104546-89-5, 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedioneRelated Search:

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

BYK 204165

4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione

PARP Inhibitor XIV

4-(1-Methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinoline-1,3-dione

RT-017290

1,3(2H,4H)-Isoquinolinedione, 4-[(1-methyl-1H-pyrrol-2-yl)methylene]-

BYK204165 >=98% (HPLC)

4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione

BYK-204165,poly ADP ribose polymerase,Inhibitor,PARP,antitumor,inhibit,BYK204165,BYK 204165

1104546-89-5