trans-Ned 19
- Product Name
- trans-Ned 19
- CAS No.
- 1354235-96-3
- Chemical Name
- trans-Ned 19
- Synonyms
- trans-Ned 19;transNed 19,trans Ned 19;(1R,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid;(1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]Methyl]-4-Methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)-
- CBNumber
- CB62546793
- Molecular Formula
- C30H31FN4O3
- Formula Weight
- 514.59
- MOL File
- 1354235-96-3.mol
trans-Ned 19 Property
- Melting point:
- 168-173°C
- Boiling point:
- 715.1±60.0 °C(Predicted)
- Density
- 1.316±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Methanol
- form
- Solid
- pka
- 2.17±0.40(Predicted)
- color
- Yellow
N-Bromosuccinimide Price
- Product number
- 17527
- Product name
- trans-Ned-19
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 17527
- Product name
- trans-Ned-19
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
- Product number
- 17527
- Product name
- trans-Ned-19
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $321
- Updated
- 2024/03/01
- Product number
- 3954
- Product name
- trans-Ned19
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $335
- Updated
- 2021/12/16
- Product number
- N388750
- Product name
- trans-Ned-19
- Packaging
- 50mg
- Price
- $1135
- Updated
- 2021/12/16
trans-Ned 19 Chemical Properties,Usage,Production
Chemical Properties
Yellow Solid
Uses
trans-Ned-19 is a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells.
Definition
ChEBI: Trans-Ned 19 is a member of the class of beta-carbolines that is 2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid in which one of the methylene protons at position 1 has been replaced by a 3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-methoxyphenyl group. It has a role as a nicotinic acid adenine dinucleotide phosphate receptor antagonist. It is a member of beta-carbolines, an alpha-amino acid, a monomethoxybenzene, a member of monofluorobenzenes and a N-arylpiperazine.
storage
Store at -20°C