1-(3-Methoxypropyl)-4-piperidinamine
- Product Name
- 1-(3-Methoxypropyl)-4-piperidinamine
- CAS No.
- 179474-79-4
- Chemical Name
- 1-(3-Methoxypropyl)-4-piperidinamine
- Synonyms
- Prucalopride intermediateB;4-AMino-1-(3-Methoxypropy...;Prucalopride Succinate iMpuritO;3-methoxy propyl piperidinamine;1-(3-methoxypropyl) -4-piperidine;1-(3-Methoxypropyl)-4-piperidimine;1-(3-Methoxypropyl)piperidin-4-aMine;1-(3-Methoxypropyl)-4-piperidinamine;Prucalopride Succinate interMediate B;4-AMino-1-(3-Methoxypropyl)piperidine
- CBNumber
- CB62589756
- Molecular Formula
- C9H20N2O
- Formula Weight
- 172.27
- MOL File
- 179474-79-4.mol
1-(3-Methoxypropyl)-4-piperidinamine Property
- Boiling point:
- 249℃
- Density
- 0.946
- Flash point:
- 105℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- 10.49±0.20(Predicted)
- color
- Colourless to Pale Yellow
- InChI
- InChI=1S/C9H20N2O/c1-12-8-2-5-11-6-3-9(10)4-7-11/h9H,2-8,10H2,1H3
- InChIKey
- HIXAJGFVNMKLML-UHFFFAOYSA-N
- SMILES
- N1(CCCOC)CCC(N)CC1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- Y1133
- Product name
- 1-(3-methoxypropyl)piperidin-4-amine
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- Y1133
- Product name
- 1-(3-methoxypropyl)piperidin-4-amine
- Packaging
- 10g
- Price
- $236
- Updated
- 2021/12/16
- Product number
- 115680
- Product name
- 4-Amino-1-(3-methoxypropyl)piperidine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $572
- Updated
- 2021/12/16
- Product number
- 115680
- Product name
- 4-Amino-1-(3-methoxypropyl)piperidine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1580
- Updated
- 2021/12/16
- Product number
- 115680
- Product name
- 4-Amino-1-(3-methoxypropyl)piperidine
- Purity
- 95+%
- Packaging
- 10g
- Price
- $2222
- Updated
- 2021/12/16
1-(3-Methoxypropyl)-4-piperidinamine Chemical Properties,Usage,Production
Uses
1-(3-Methoxypropyl)-4-piperidinamine is a useful synthetic intermediate in the synthesis of Prucalopride Succinate (P838950); a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
Synthesis
N-(1-(3-methoxypropyl)piperidin-4-yl)acetamide (10.72g, 0.05mol) was added to HCl-methanol solution (0.5M, 180ml), and the temperature was controlled at 2025°C After the reaction was detected, it was filtered, and the filter cake was washed with dichloromethane and dried to obtain 1-(3-Methoxypropyl)-4-piperidinamine with a yield of 96.4% and a purity of 99.7%.
1-(3-Methoxypropyl)-4-piperidinamine Preparation Products And Raw materials
Raw materials
Preparation Products
1-(3-Methoxypropyl)-4-piperidinamine Suppliers
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View Lastest Price from 1-(3-Methoxypropyl)-4-piperidinamine manufacturers
- Product
- 1-(3-Methoxypropyl)-4-piperidinamine 179474-79-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000KG
- Release date
- 2024-07-24
- Product
- 1-(3-Methoxypropyl)-4-piperidinamine 179474-79-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 800KGS/month
- Release date
- 2024-07-09
- Product
- 1-(3-Methoxypropyl)-4-piperidinamine 179474-79-4
- Price
- US $6.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-28