CAY10574

Product Name: CAY10574
CAS No.: 140651-18-9
Chemical Name: CAY10574
Synonyms: CAN-508;CAY10574;Cdk9 Inhibitor II;CAN-508 (CAN508);4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol;4-[2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]phenol;Phenol, 4-[2-(3,5-diamino-1H-pyrazol-4-yl)diazenyl]-;CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem;inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,adenocarcinoma,HT-29,CAN-508
CBNumber: CB62590428
Molecular Formula: C9H10N6O
Formula Weight: 218.22
MOL File: 140651-18-9.mol

More

Less

CAY10574 Property

Boiling point:: 638.3±55.0 °C(Predicted)
Density: 1.67±0.1 g/cm3(Predicted)
storage temp.: +2C to +8C
solubility: DMF: 0.5 mg/ml; DMSO: 0.5 mg/ml
pka: 8.52±0.30(Predicted)
form: Yellow semi-solid
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 238811
Product name: Cdk9 Inhibitor II - CAS 140651-18-9 - Calbiochem
Packaging: 5mg
Price: $289
Updated: 2024/03/01

Cayman Chemical

Product number: 10011247
Product name: CAY10574
Purity: ≥95%
Packaging: 1mg
Price: $25
Updated: 2024/03/01

Cayman Chemical

Product number: 10011247
Product name: CAY10574
Purity: ≥95%
Packaging: 5mg
Price: $107
Updated: 2024/03/01

Cayman Chemical

Product number: 10011247
Product name: CAY10574
Purity: ≥95%
Packaging: 10mg
Price: $186
Updated: 2024/03/01

Cayman Chemical

Product number: 10011247
Product name: CAY10574
Purity: ≥95%
Packaging: 50mg
Price: $807
Updated: 2024/03/01

More

Less

CAY10574 Chemical Properties,Usage,Production

Uses

Cdk9 Inhibitor II is an ATP-competitive inhibitor of Cdk9 and moderate inhibitor of similar enzymes.

Definition

ChEBI: CAN-508 is a member of the class of pyrazoles that is 1H-pyrazole substituted by amino, (4-hydroxyphenyl)diazenyl, and amino groups at positions 3, 4 and 5, respectively. It is a CDK9 inhibitor (IC50 = 0.35 muM) with 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. It has a role as an angiogenesis inhibitor, an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a member of pyrazoles, a member of phenols, an aromatic amine and a monoazo compound.

General Description

A cell-permeable Olomoucine (Cat. Nos. 495620 & 495624) analog that acts as a CaMKII inhibitor (IC₅₀<10 μM) and inhibits insulin-stimulated glucose uptake (IC₅₀ ≤5 μM) and GLUT4 membrane translocation (IC₅₀ = 100 μM) in 3T3-L1 adipocytes.

CAY10574 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CAY10574 Suppliers

Canada 1 China 36 Ukraine 1 United States 8 Global 46

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 4602
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6312
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

140651-18-9, CAY10574Related Search:

CAY10574

Cdk9 Inhibitor II

4-[2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]phenol

CAN-508

CAN-508 (CAN508)

CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem

inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,adenocarcinoma,HT-29,CAN-508

Phenol, 4-[2-(3,5-diamino-1H-pyrazol-4-yl)diazenyl]-

4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol

140651-18-9