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Lipoxygenase Inhibitor Screening Assay Kit

Product Name
Lipoxygenase Inhibitor Screening Assay Kit
Chemical Name
Lipoxygenase Inhibitor Screening Assay Kit
Synonyms
Lipoxygenase Inhibitor Screening Assay Kit
CBNumber
CB62591612
Formula Weight
0
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
760700
Product name
Lipoxygenase Inhibitor Screening Assay Kit
Packaging
96Well
Price
$217
Updated
2024/03/01
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Lipoxygenase Inhibitor Screening Assay Kit Chemical Properties,Usage,Production

Description

Lipoxygenases are members of a class of non-heme iron-containing dioxygenases that catalyze the addition of molecular oxygen to fatty acids containing a cis,cis-1,4-pentadiene system to give an unsaturated fatty acid hydroperoxide. In mammals, lipoxygenases carry out the first step in the arachidonic acid cascade.1,2 5- and 15-LOs lead to the biologically active lipoxins, whereas 5-LO leads to 5,6-epoxy-leukotrienes which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction.3 In contrast, Nassar, et al., suggested that animal 15-LO products act as anti-inflammatory agents.4 This implies that the 5- and 15-LO pathways may play a role in regulating inflammation. To elucidate the role of each lipoxygenase, it is particularly important to develop inhibitors that are enzyme specific. This assay kit provides an accurate and convenient method for screening lipoxygenase inhibitors. This assay measures the hydroperoxides generated from the incubation of a lipoxygenase (5-, 12-, or 15-LO) with either arachidonic or linoleic acid.Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.WARNING This product is not for human or veterinary use.

Lipoxygenase Inhibitor Screening Assay Kit Preparation Products And Raw materials

Raw materials

Preparation Products

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Lipoxygenase Inhibitor Screening Assay Kit Suppliers

amyjet
Tel
4006800868;027-59626688 18371453821;18771149750
Email
sales@amyjet.com
Country
China
ProdList
2917
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58
Hubei Aiputi Bioengineering Co., Ltd.
Tel
17762444226
Email
d17762444226@163.com
Country
China
ProdList
2402
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
Langfang Yusheng Ruichuang Technology Co., Ltd.
Tel
17398520978
Country
CHINA
ProdList
157
Advantage
58

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