3-broMo-5-Methanesulfonylaniline
- Product Name
- 3-broMo-5-Methanesulfonylaniline
- CAS No.
- 62606-00-2
- Chemical Name
- 3-broMo-5-Methanesulfonylaniline
- Synonyms
- 3-broMo-5-Methanesulfonylaniline;3-BroMo-5-(Methylsulfonyl)aniline;3-Bromo-5-(methylsulphonyl)aniline;3-Bromo-5-(methylsulfonyl)benzenamine;3-Bromo-5-(methylsulphonyl)aniline 98%;Benzenamine, 3-bromo-5-(methylsulfonyl)-;3-bromo-5-methylsulfonyl-aniline - [B87119]
- CBNumber
- CB62595650
- Molecular Formula
- C7H8BrNO2S
- Formula Weight
- 250.11
- MOL File
- 62606-00-2.mol
3-broMo-5-Methanesulfonylaniline Property
- Boiling point:
- 452.9±45.0 °C(Predicted)
- Density
- 1.671±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 1.58±0.10(Predicted)
- Appearance
- White to yellow Solid
Safety
- HS Code
- 2921420090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- FB143485
- Product name
- 3-Bromo-5-(methylsulfonyl)aniline
- Packaging
- 25mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FB143485
- Product name
- 3-Bromo-5-(methylsulfonyl)aniline
- Packaging
- 50mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- 8663-9-05
- Product name
- 3-Bromo-5-(methylsulfonyl)aniline
- Packaging
- 250mg
- Price
- $116
- Updated
- 2021/12/16
- Product number
- FB143485
- Product name
- 3-Bromo-5-(methylsulfonyl)aniline
- Packaging
- 100mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FB143485
- Product name
- 3-Bromo-5-(methylsulfonyl)aniline
- Packaging
- 250mg
- Price
- $200
- Updated
- 2021/12/16
3-broMo-5-Methanesulfonylaniline Chemical Properties,Usage,Production
Uses
3-Bromo-5-(methylsulfonyl)aniline is used in the preparation of WDR5-?MYC inhibitors.
Synthesis
62606-15-9
62606-00-2
General procedure for the synthesis of 3-bromo-5-(methylsulfonyl)aniline from 1-bromo-3-(methylsulfonyl)-5-nitrobenzene: 1-bromo-3-(methylsulfonyl)-5-nitrobenzene (100 mg, 0.4 mmol) was dissolved in tetrahydrofuran (THF, 10 mL). Raney nickel catalyst was added and the hydrogenation reaction was carried out under 1 bar hydrogen pressure. Upon completion of the reaction, the mixture was filtered to remove the catalyst and the filtrate was subsequently concentrated. 3-Bromo-5-(methylsulfonyl)aniline (30 mg, 0.16 mmol, 40% yield) was finally obtained as a yellow solid.
References
[1] Patent: EP1953163, 2008, A1. Location in patent: Page/Page column 13
[2] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1977, p. 14 - 17
3-broMo-5-Methanesulfonylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
3-broMo-5-Methanesulfonylaniline Suppliers
- Tel
- 0551-66399836 18955197623
- sales@enlipharma.com
- Country
- China
- ProdList
- 1876
- Advantage
- 55
- Tel
- 021-20960837
- Fax
- 021-20960837
- market@aloespharm.com
- Country
- China
- ProdList
- 1302
- Advantage
- 55
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 18652960783
- Fax
- -
- 2944805124@qq.com
- Country
- China
- ProdList
- 35
- Advantage
- 55
- Tel
- 021-20960837,QQ1332204249
- Fax
- 021-20960837
- sales@skychemical.com
- Country
- China
- ProdList
- 3341
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- 025-66061636 18013972705
- Fax
- (3)02557626880
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 15814
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58