6-Boc-2-oxo-6-aza-spiro[3.4]octane
- Product Name
- 6-Boc-2-oxo-6-aza-spiro[3.4]octane
- CAS No.
- 203661-71-6
- Chemical Name
- 6-Boc-2-oxo-6-aza-spiro[3.4]octane
- Synonyms
- 6-Boc-6-azaspiro[3.4]octan-2-one;benzyl 2-oxo-6-azaspiro[3.4]octane-6-carboxylate;6-Boc-2-oxo-6-aza-spiro[3...;6-Boc-2-oxo-6-aza-spiro[3.4]octane;6-N-Boc-2-oxo-6-aza-spiro[3.4]octane;6-Azaspiro[3.4]octan-2-one,N-BOCprotected;tert-Butyl 2-oxo-7-azaspiro[3.4]octane-7-carboxylate;2-Oxo-6-aza-spiro[3.4]octane-6-carboxylic acid tert-butyl-ester;2-oxo-6-Azaspiro[3.4]octane-6-carboxylic acid 1,1-dimethylethyl ester;2-Oxo-6-aza-spiro[3.4]octane-6-carboxylic acid tert-butyl-ester - X7188
- CBNumber
- CB62597210
- Molecular Formula
- C12H19NO3
- Formula Weight
- 225.28
- MOL File
- 203661-71-6.mol
6-Boc-2-oxo-6-aza-spiro[3.4]octane Property
- Boiling point:
- 331.8±35.0 °C(Predicted)
- Density
- 1.14±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- -0.80±0.20(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C12H19NO3/c1-11(2,3)16-10(15)13-5-4-12(8-13)6-9(14)7-12/h4-8H2,1-3H3
- InChIKey
- WQPZESPYNGQLQA-UHFFFAOYSA-N
- SMILES
- C1C2(CCN(C(OC(C)(C)C)=O)C2)CC1=O
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- B872348
- Product name
- tert-butyl2-oxo-6-azaspiro[3.4]octane-6-carboxylate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB162618
- Product name
- 6-Boc-2-oxo-6-aza-spiro[3.4]octane
- Packaging
- 500mg
- Price
- $230
- Updated
- 2021/12/16
- Product number
- FB162618
- Product name
- 6-Boc-2-oxo-6-aza-spiro[3.4]octane
- Packaging
- 100mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FB162618
- Product name
- 6-Boc-2-oxo-6-aza-spiro[3.4]octane
- Packaging
- 250mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- CHM0395784
- Product name
- 2-OXO-6-AZA-SPIRO-[3.4]OCTANE-6-CARBOXYLIC ACID TERT-BUTYL-ESTER
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $647.85
- Updated
- 2021/12/16
6-Boc-2-oxo-6-aza-spiro[3.4]octane Chemical Properties,Usage,Production
Synthesis
1558037-99-2
203661-71-6
1.21 mol) and zinc powder (Zn, 79.1 g, 1.21 mol). The reaction mixture was stirred at room temperature for 8 hours. After completion of the reaction, the mixture was treated with distilled water (H2O) and extracted with ethyl acetate (EtOAc). The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The crude product was purified by fast column chromatography (silica gel, eluent: petroleum ether to 25% ethyl acetate in petroleum ether solution) to afford the target product R-5 (19 g, 69% yield).
References
[1] Patent: US2014/45813, 2014, A1. Location in patent: Paragraph 0113
[2] Patent: US2014/275014, 2014, A1. Location in patent: Paragraph 0128; 0129; 0132
[3] Patent: WO2015/116485, 2015, A1. Location in patent: Page/Page column 24; 25
6-Boc-2-oxo-6-aza-spiro[3.4]octane Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Boc-2-oxo-6-aza-spiro[3.4]octane manufacturers
- Product
- 6-Boc-2-oxo-6-aza-spiro[3.4]octane 203661-71-6
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-07-09