ChemicalBook > CAS DataBase List > 6-Boc-2-oxo-6-aza-spiro[3.4]octane

6-Boc-2-oxo-6-aza-spiro[3.4]octane

Product Name
6-Boc-2-oxo-6-aza-spiro[3.4]octane
CAS No.
203661-71-6
Chemical Name
6-Boc-2-oxo-6-aza-spiro[3.4]octane
Synonyms
6-Boc-6-azaspiro[3.4]octan-2-one;benzyl 2-oxo-6-azaspiro[3.4]octane-6-carboxylate;6-Boc-2-oxo-6-aza-spiro[3...;6-Boc-2-oxo-6-aza-spiro[3.4]octane;6-N-Boc-2-oxo-6-aza-spiro[3.4]octane;6-Azaspiro[3.4]octan-2-one,N-BOCprotected;tert-Butyl 2-oxo-7-azaspiro[3.4]octane-7-carboxylate;2-Oxo-6-aza-spiro[3.4]octane-6-carboxylic acid tert-butyl-ester;2-oxo-6-Azaspiro[3.4]octane-6-carboxylic acid 1,1-dimethylethyl ester;2-Oxo-6-aza-spiro[3.4]octane-6-carboxylic acid tert-butyl-ester - X7188
CBNumber
CB62597210
Molecular Formula
C12H19NO3
Formula Weight
225.28
MOL File
203661-71-6.mol
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6-Boc-2-oxo-6-aza-spiro[3.4]octane Property

Boiling point:
331.8±35.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
-0.80±0.20(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C12H19NO3/c1-11(2,3)16-10(15)13-5-4-12(8-13)6-9(14)7-12/h4-8H2,1-3H3
InChIKey
WQPZESPYNGQLQA-UHFFFAOYSA-N
SMILES
C1C2(CCN(C(OC(C)(C)C)=O)C2)CC1=O
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
B872348
Product name
tert-butyl2-oxo-6-azaspiro[3.4]octane-6-carboxylate
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB162618
Product name
6-Boc-2-oxo-6-aza-spiro[3.4]octane
Packaging
500mg
Price
$230
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB162618
Product name
6-Boc-2-oxo-6-aza-spiro[3.4]octane
Packaging
100mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB162618
Product name
6-Boc-2-oxo-6-aza-spiro[3.4]octane
Packaging
250mg
Price
$150
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0395784
Product name
2-OXO-6-AZA-SPIRO-[3.4]OCTANE-6-CARBOXYLIC ACID TERT-BUTYL-ESTER
Purity
95.00%
Packaging
1G
Price
$647.85
Updated
2021/12/16
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6-Boc-2-oxo-6-aza-spiro[3.4]octane Chemical Properties,Usage,Production

Synthesis

1558037-99-2

203661-71-6

1.21 mol) and zinc powder (Zn, 79.1 g, 1.21 mol). The reaction mixture was stirred at room temperature for 8 hours. After completion of the reaction, the mixture was treated with distilled water (H2O) and extracted with ethyl acetate (EtOAc). The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The crude product was purified by fast column chromatography (silica gel, eluent: petroleum ether to 25% ethyl acetate in petroleum ether solution) to afford the target product R-5 (19 g, 69% yield).

References

[1] Patent: US2014/45813, 2014, A1. Location in patent: Paragraph 0113
[2] Patent: US2014/275014, 2014, A1. Location in patent: Paragraph 0128; 0129; 0132
[3] Patent: WO2015/116485, 2015, A1. Location in patent: Page/Page column 24; 25

6-Boc-2-oxo-6-aza-spiro[3.4]octane Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Boc-2-oxo-6-aza-spiro[3.4]octane Suppliers

Shandong Shenganbei New Energy Co. , Ltd. . Nanjing branch
Tel
18761883648
Email
sab202211@163.com
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China
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1665
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Jiangsu Synthesis Bio-Tech Co., LTD
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13761708290
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13761708290@163.com
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China
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58
Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
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Changzhou Huanling Chemical Co., Ltd.
Tel
0519-89803565 13776850645
Fax
0519-89803575
Email
info4@huanlingchem.com
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China
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Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
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China
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Nanjing Habo Medical Technology Co., Ltd.
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025-85760892 13376080562
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025-85766769
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China
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Tetranov Biopharm
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13526569071
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sales@leadmedpharm.com
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China
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Adamas Reagent, Ltd.
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400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
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Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
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info@topbiochem.com
Country
China
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View Lastest Price from 6-Boc-2-oxo-6-aza-spiro[3.4]octane manufacturers

Career Henan Chemical Co
Product
6-Boc-2-oxo-6-aza-spiro[3.4]octane 203661-71-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-07-09

203661-71-6, 6-Boc-2-oxo-6-aza-spiro[3.4]octaneRelated Search:


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  • 6-Azaspiro[3.4]octan-2-one,N-BOCprotected
  • 6-N-Boc-2-oxo-6-aza-spiro[3.4]octane
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  • tert-Butyl 2-oxo-7-azaspiro[3.4]octane-7-carboxylate
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  • 6-Boc-6-azaspiro[3.4]octan-2-one
  • benzyl 2-oxo-6-azaspiro[3.4]octane-6-carboxylate
  • 203661-71-6