2,2,2-trifluoro-1-p-tolylethanol
- Product Name
- 2,2,2-trifluoro-1-p-tolylethanol
- CAS No.
- 446-65-1
- Chemical Name
- 2,2,2-trifluoro-1-p-tolylethanol
- Synonyms
- 2,2,2-trifluoro-1-p-tolylethano;2,2,2-trifluoro-1-p-tolylethanol;Benzenemethanol, 4-methyl-α-(trifluoromethyl)-;alpha-(Trifluoromethyl)-4-methylbenzyl Alcohol
- CBNumber
- CB62604594
- Molecular Formula
- C9H9F3O
- Formula Weight
- 190.16
- MOL File
- 446-65-1.mol
2,2,2-trifluoro-1-p-tolylethanol Property
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Appearance
- Colorless to off-white Solid-Liquid Mixture
Safety
- HS Code
- 2906290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T899393
- Product name
- 2,2,2-Trifluoro-1-(p-tolyl)ethanol
- Packaging
- 100mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 1839AL
- Product name
- 2,2,2-Trifluoro-1-(p-tolyl)ethanol
- Packaging
- 1g
- Price
- $172
- Updated
- 2021/12/16
- Product number
- PC201255
- Product name
- 2,2,2-Trifluoro-1-(p-tolyl)ethanol
- Purity
- 98%
- Packaging
- 1g
- Price
- $186
- Updated
- 2021/12/16
- Product number
- PC201255
- Product name
- 2,2,2-Trifluoro-1-(p-tolyl)ethanol
- Purity
- 98%
- Packaging
- 250mg
- Price
- $74
- Updated
- 2021/12/16
- Product number
- HCH0052309
- Product name
- 2,2,2-TRIFLUORO-1-(4-METHYLPHENYL)ETHANOL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $852.55
- Updated
- 2021/12/16
2,2,2-trifluoro-1-p-tolylethanol Chemical Properties,Usage,Production
Synthesis
104-87-0
446-65-1
General procedure for the synthesis of 2,2,2-trifluoro-1-(p-tolyl)ethanol from p-toluylbenzaldehyde: 0.1 mL of a 1.0 M tetrahydrofuran solution of tetrabutylammonium fluoride was added to a 10 mL solution of THF containing 4-methylbenzaldehyde (1.2 g, 10 mmol) and TMSCF3 (1.8 mL, 12 mmol) at 0 °C. The reaction mixture was gradually warmed to room temperature and stirred continuously for 4 hours. Subsequently, the reaction mixture was treated with 12 mL of 1N HCl and stirring was continued overnight. After completion of the reaction, the product was extracted with ethyl acetate (3 x 20 mL). The organic layer was separated and dried with anhydrous sodium sulfate. Finally, the organic solvent was removed by evaporation to give 1.6 g of 1-(4-methylphenyl)-2,2,2-trifluoroethanol in 86% yield.
References
[1] Patent: US2009/5381, 2009, A1
[2] Patent: US2009/5382, 2009, A1
[3] Patent: US2009/29993, 2009, A1
[4] Journal of Organic Chemistry, 2013, vol. 78, # 2, p. 711 - 716
[5] Patent: WO2018/39386, 2018, A1. Location in patent: Page/Page column 288
2,2,2-trifluoro-1-p-tolylethanol Preparation Products And Raw materials
Raw materials
Preparation Products
2,2,2-trifluoro-1-p-tolylethanol Suppliers
- Tel
- 13526569071
- sales@leadmedpharm.com
- Country
- China
- ProdList
- 7892
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 18-086626237 18086626237
- Fax
- qq:2693528373
- 2693528373@qq.com
- Country
- China
- ProdList
- 2973
- Advantage
- 56
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 025-66061636 18013972705
- Fax
- (3)02557626880
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 15814
- Advantage
- 58
- Tel
- 400-8210725 400821072
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 25000
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- 15021845385
- 765325601@qq.com
- Country
- China
- ProdList
- 3609
- Advantage
- 58
View Lastest Price from 2,2,2-trifluoro-1-p-tolylethanol manufacturers
- Product
- 222-trifluoro-1-p-tolylethanol 446-65-1
- Price
- US $1.00-28.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20000KG
- Release date
- 2024-07-29