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Heterophyllin B

Product Name
Heterophyllin B
CAS No.
145459-19-4
Chemical Name
Heterophyllin B
Synonyms
Heterophylin B;Heterophyllin B;Prince Ginseng Cyclic Peptide B;Cyclo(glycylglycyl-L-leucyl-L-prolyl-L-prolyl-L-prolyl-L-isoleucyl-L-phenylalanyl);Cyclo(glycylglycyl-L-isoleucyl-L-prolyl-L-prolyl-L-prolyl-L-isole ucyl-L-phenylalanyl);(6S,15S,18S,20aS,25aS,30aS)-15-Benzyl-18-((S)-sec-butyl)-6-isobutylicosahydro-1H,25H-tripyrrolo[1,2-a:1',2'-d:1'',2''-g][1,4,7,10,13,16,19,22]octaazacyclotetracosin-5,8,11,14,17,20,25,30(30aH)-octaone;(6S,15S,18S,20aS,25aS,30aS)-15-Benzyl-18-((S)-sec-butyl)-6-isobutylicosahydro-1H,25H-tripyrrolo[1,2-a:1',2'-d:1'',2''-g][1,4,7,10,13,16,19,22]octaazacyclotetracosin-5,8,11,14,17,20,25,30(30aH)-octaone
CBNumber
CB62604877
Molecular Formula
C40H58N8O8
Formula Weight
778.94
MOL File
145459-19-4.mol
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Heterophyllin B Property

Boiling point:
1159.7±65.0 °C(Predicted)
Density 
1.29±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
4°C, protect from light
solubility 
Soluble in DMSO
pka
13.44±0.70(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
300415
Product name
Heterophyllin B
Packaging
20mg
Price
$490
Updated
2021/12/16
ChemScene
Product number
CS-0016982
Product name
HeterophyllinB
Purity
≥98.0%
Packaging
5mg
Price
$184
Updated
2021/12/16
ChemScene
Product number
CS-0016982
Product name
HeterophyllinB
Purity
≥98.0%
Packaging
10mg
Price
$320
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594002
Product name
Heterophyllin B
Packaging
20mg
Price
$391
Updated
2021/12/16
Biorbyt Ltd
Product number
orb105560
Product name
Heterophyllin B
Purity
>98%
Packaging
20mg
Price
$569.5
Updated
2021/12/16
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Heterophyllin B Chemical Properties,Usage,Production

Chemical Properties

White crystal, easily soluble in methanol, derived from Radix Radix.

Uses

Taizishencyclopeptide B has the functions of invigorating qi and blood, invigorating body fluid and invigorating the spleen and stomach. And it was used for content determination/identification/pharmacological experiments, etc.

Biological Activity

Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. It can be used in esophageal cancer research.

in vitro

Heterophyllin B (0-200 μM; 12-48 hours) reduces cell viability in the 75, 100 and 200 μM groups, has no effect on 5, 10, 25 and 50 μM groups.Heterophyllin B (0 -50 μM; 6 hours) suppresses the expression levels of p-PI3K, p-AKT and β-catenin in a dose-dependent manner in ECA-109 cells.

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Cell Viability Assay

Cell Line: ECA-109 cells
Concentration: 5 μM, 10 μM, 25 μM, 50 μM, 75 μM, 100 μM and 200 μM
Incubation Time: 12, 24 and 48 hours
Result: Decrease cell viability at high concentrations.

Western Blot Analysis

Cell Line: ECA-109 cells
Concentration: 0 μM, 10 μM, 25 μM, 50 μM
Incubation Time: 6 hours
Result: Decreased the phosphorylation of PI3K/AKT and the expression of β-catenin.

Heterophyllin B Preparation Products And Raw materials

Raw materials

Preparation Products

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Heterophyllin B Suppliers

Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Cheng Du Pufeide Biotechnology Co., Ltd.
Tel
028-82610909 13388174823
Fax
8171-1798
Email
scglp@glp-china.com
Country
China
ProdList
1064
Advantage
58
Chengdu Herbpurify Co.Ltd.
Tel
18302802153 18981717076
Fax
086-28-85377358
Email
2355253619@qq.com
Country
China
ProdList
1104
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Shanghai Aspire Biological Technology Co., Ltd.
Tel
021-61317773
Fax
021-61486878
Email
sales@aspirebio.com
Country
China
ProdList
2880
Advantage
58
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
ALB Technology Limited
Tel
702-983-3769
Fax
702-983-3769
Email
sales@albtechnology.com
Country
United States
ProdList
2993
Advantage
55
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
6905
Advantage
55
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View Lastest Price from Heterophyllin B manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Heterophyllin B 145459-19-4
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-12-12
Career Henan Chemical Co
Product
Heterophyllin B 145459-19-4
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg , 5kg, 50kg
Release date
2020-01-17

145459-19-4, Heterophyllin BRelated Search:


  • Heterophyllin B
  • Heterophylin B
  • Prince Ginseng Cyclic Peptide B
  • Cyclo(glycylglycyl-L-isoleucyl-L-prolyl-L-prolyl-L-prolyl-L-isole ucyl-L-phenylalanyl)
  • Cyclo(glycylglycyl-L-leucyl-L-prolyl-L-prolyl-L-prolyl-L-isoleucyl-L-phenylalanyl)
  • (6S,15S,18S,20aS,25aS,30aS)-15-Benzyl-18-((S)-sec-butyl)-6-isobutylicosahydro-1H,25H-tripyrrolo[1,2-a:1',2'-d:1'',2''-g][1,4,7,10,13,16,19,22]octaazacyclotetracosin-5,8,11,14,17,20,25,30(30aH)-octaone
  • (6S,15S,18S,20aS,25aS,30aS)-15-Benzyl-18-((S)-sec-butyl)-6-isobutylicosahydro-1H,25H-tripyrrolo[1,2-a:1',2'-d:1'',2''-g][1,4,7,10,13,16,19,22]octaazacyclotetracosin-5,8,11,14,17,20,25,30(30aH)-octaone
  • 145459-19-4
  • C40H58N8O8
  • reagent
  • standard substance