ChemicalBook > CAS DataBase List > 3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one

3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one

Product Name
3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one
CAS No.
181525-38-2
Chemical Name
3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one
Synonyms
Paliperidone-4;Paliperidone Impurities12;Paliperidone Impurities109;9-hydroxy-3-(2-hydroxyethyl);Paliperidone Tetradehydro Hydroxyethyl Impurity;9-hydroxy-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-a]pyrimi...;9-Hydroxy-3-(2-hydroxyethyl)-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one;3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one;4H-Pyrido[1,2-a]pyrimidin-4-one, 9-hydroxy-3-(2-hydroxyethyl)-2-methyl-;Paliperidone impurity 20/9-hydroxy-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CBNumber
CB62605586
Molecular Formula
C11H12N2O3
Formula Weight
220.22
MOL File
181525-38-2.mol
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3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Property

Melting point:
145-148°C
Boiling point:
437.4±55.0 °C(Predicted)
Density 
1.38±0.1 g/cm3(Predicted)
vapor pressure 
0-0Pa at 20-25℃
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
8.09±0.20(Predicted)
form 
Solid
color 
Beige
LogP
0.19 at 20℃ and pH7
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H341Suspected of causing genetic defects

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
H943115
Product name
9-Hydroxy-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Packaging
25mg
Price
$185
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
70690
Product name
9-Hydroxy-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-α]pyrimidin-4-one
Packaging
250mg
Price
$2200
Updated
2021/12/16
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3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Chemical Properties,Usage,Production

Uses

9-Hydroxy-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is an intermediate in the synthesis of analog of Paliperidone, a combined serotonin and dopamine receptor antagonist.

3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Suppliers

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181525-38-2, 3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-oneRelated Search:

9-Keto Risperidone 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 3-Ethyl-6,7,8,9-tetrahydro-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Paliperidone N-Oxide 9-hydroxy-2-methyl-3-vinyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one Paliperidone (R)-9-Hydroxy Risperidone 5-Fluoro Paliperidone 9-Benxyloxy-3-(2-Chloro ethyl)-2-methyl pyrido[1,2-a]pyrimidine-4-one (S)-9-Hydroxy Risperidone 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride 3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone) 3-ethyl-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Paliperidone Desfluoro Impurity 9-(benzyloxy)-3-(2-hydroxyethyl)-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one

  • 3-(2-Hydroxyethyl)-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one
  • 9-Hydroxy-3-(2-hydroxyethyl)-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one
  • Paliperidone-4
  • Paliperidone impurity 20/9-hydroxy-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
  • 9-hydroxy-3-(2-hydroxyethyl)
  • Paliperidone Tetradehydro Hydroxyethyl Impurity
  • 4H-Pyrido[1,2-a]pyrimidin-4-one, 9-hydroxy-3-(2-hydroxyethyl)-2-methyl-
  • 9-hydroxy-3-(2-hydroxyethyl)-2-methyl-4H-pyrido[1,2-a]pyrimi...
  • Paliperidone Impurities109
  • Paliperidone Impurities12
  • 181525-38-2