4-c]pyridine
- Product Name
- 4-c]pyridine
- CAS No.
- 1082040-63-8
- Chemical Name
- 4-c]pyridine
- Synonyms
- EOS-60837;3-Iodo-1H-pyrazolo[3;3-Iodo-6-azaindazole;3-iodo-1H-pyrazolo[3,5-c]pyridine;3-Iodo-1H-pyrazolo[3,4-c]pyridine;1H-Pyrazolo[3,4-c]pyridine, 3-iodo-;3-Iodo-1H-pyrazolo[3,4-c]pyridine 98%
- CBNumber
- CB62616384
- Molecular Formula
- C6H4IN3
- Formula Weight
- 245.02
- MOL File
- 1082040-63-8.mol
4-c]pyridine Property
- Boiling point:
- 401.3±25.0 °C(Predicted)
- Density
- 2.219±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 8.98±0.40(Predicted)
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I706410
- Product name
- 3-Iodo-1H-pyrazolo[3,4-c]pyridine
- Packaging
- 1g
- Price
- $330
- Updated
- 2021/12/16
- Product number
- OR52040
- Product name
- 3-Iodo-1H-pyrazolo[3,4-c]pyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $240
- Updated
- 2021/12/16
- Product number
- 123972
- Product name
- 3-Iodo-1H-pyrazolo[3,4-c]pyridine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $435
- Updated
- 2021/12/16
- Product number
- 1640AA
- Product name
- 3-Iodo-1H-pyrazolo[3,4-c]pyridine
- Packaging
- 1g
- Price
- $637
- Updated
- 2021/12/16
- Product number
- OR52040
- Product name
- 3-Iodo-1H-pyrazolo[3,4-c]pyridine
- Purity
- 98%
- Packaging
- 5g
- Price
- $711
- Updated
- 2021/12/16
4-c]pyridine Chemical Properties,Usage,Production
Synthesis
271-47-6
1082040-63-8
General procedure for the synthesis of 3-iodo-1H-pyrazolo[3,4-c]pyridine from 1H-pyrazolo[3,4-c]pyridine: 1H-pyrazolo[3,4-c]pyridine (300 mg, 2.52 mmol, 1.00 eq.), potassium hydroxide (KOH, 500 mg, 8.91 mmol, 3.50 eq.) and diiodomethane (1.28 g, 1.28 g, 2.00 eq.) were suspended in N,N-dimethylformamide (DMF, 10 mL). 5.04 mmol, 2.00 eq.) were suspended in N,N-dimethylformamide (DMF, 10 mL). The reaction mixture was stirred overnight at room temperature. After completion of the reaction, the reaction was quenched with water, the organic phase was extracted with ethyl acetate, the organic layer was dried with anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent ethyl acetate/petroleum ether (1:1, v/v) to afford 3-iodo-1H-pyrazolo[3,4-c]pyridine (577 mg, 84% yield) as a yellow solid.LC-MS (ESI, m/z): 246 [M + H]+.
References
[1] Patent: WO2015/25025, 2015, A1. Location in patent: Page/Page column 357
[2] Patent: WO2017/98328, 2017, A2. Location in patent: Paragraph 00222
[3] Patent: WO2018/15818, 2018, A2. Location in patent: Paragraph 00177
[4] Patent: WO2012/93101, 2012, A1. Location in patent: Page/Page column 152
[5] Patent: WO2014/2053, 2014, A1. Location in patent: Page/Page column 51
4-c]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
4-c]pyridine Suppliers
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View Lastest Price from 4-c]pyridine manufacturers
- Product
- 4-c]pyridine 1082040-63-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-13
- Product
- 4-c]pyridine 1082040-63-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-13