6-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine
- Product Name
- 6-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine
- CAS No.
- 1000341-55-8
- Chemical Name
- 6-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine
- Synonyms
- 6-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine;1H-Pyrrolo[3,2-c]pyridine, 6-chloro-3-iodo-
- CBNumber
- CB82610038
- Molecular Formula
- C7H4ClIN2
- Formula Weight
- 278.48
- MOL File
- 1000341-55-8.mol
6-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine Property
- Boiling point:
- 415.4±40.0 °C(Predicted)
- Density
- 2.156±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 12.80±0.40(Predicted)
- Appearance
- Light yellow to brown Solid
N-Bromosuccinimide Price
- Product number
- C366978
- Product name
- 6-Chloro-3-iodo-5-azaindole
- Packaging
- 2mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- HCH0048116
- Product name
- 6-CHLORO-3-IODO-5-AZAINDOLE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.75
- Updated
- 2021/12/16
- Product number
- A130743
- Product name
- 6-Chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine
- Purity
- 95%
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- A130743
- Product name
- 6-Chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $105
- Updated
- 2021/12/16
- Product number
- CM149456
- Product name
- 6-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine
- Purity
- 95%+
- Packaging
- 100mg
- Price
- $110
- Updated
- 2021/12/16
6-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine Chemical Properties,Usage,Production
Synthesis
74976-31-1
1000341-55-8
General procedure for the synthesis of 3-iodo-6-chloro-1H-pyrrolo[3,2-c]pyridine from 6-chloro-5-azaindole: To a 100 mL three-necked round-bottomed flask was added a solution of N,N-dimethylformamide (10 mL) of 6-chloro-1H-pyrrolo[3,2-c]pyridine (1.00 g, 6.55 mmol), followed by the addition of potassium hydroxide (1.40 g, 24.9 mmol). The reaction mixture was stirred at room temperature for 20 minutes, then iodine (1.66 g, 6.54 mmol, 1.00 equiv) was added to the solution. The reaction mixture was continued to be stirred at room temperature for 30 minutes. Upon completion of the reaction, the reaction mixture was diluted with distilled water (50 mL) and the precipitated solid was collected by filtration. The resulting solid was dried overnight under reduced pressure to afford the target compound 6-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine (1.70 g, 93.0% yield) as a yellow solid.Results of LCMS (ESI) analysis: retention time (RT) = 1.321 min, [M + H]+ = 279, assay method=N.
References
[1] Patent: WO2014/81718, 2014, A1. Location in patent: Page/Page column 135
[2] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 7, p. 2056 - 2060
6-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
6-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine Suppliers
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3764
- Advantage
- 58
- Tel
- +86057186818502 13588463833
- Fax
- Pls mail us for more information!
- info@sagechem.com
- Country
- China
- ProdList
- 10266
- Advantage
- 58
- Tel
- 027-86697669 13986148687
- Fax
- 86-027-86697669
- sales@tcaschem.com
- Country
- China
- ProdList
- 4131
- Advantage
- 55
- Tel
- 186-33933494 18032288352
- Fax
- 0311-85310887
- 1130239@qq.com
- Country
- China
- ProdList
- 202
- Advantage
- 60
- Tel
- 027-027-87342388 18086026008
- Fax
- 027-87342388
- sales@kaymke.com
- Country
- China
- ProdList
- 3731
- Advantage
- 55
- Tel
- 027-65318838 13646286950
- sales@devinchem.com
- Country
- China
- ProdList
- 2953
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 15210642910
- moon5.1days@126.com
- Country
- China
- ProdList
- 202
- Advantage
- 56
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55