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BUTACAINE

Product Name
BUTACAINE
CAS No.
149-16-6
Chemical Name
BUTACAINE
Synonyms
Butyn;BUTACAINE;PHENBUTACAINE;Dibutylaminopropyl-p-aminobenzoate;p-Aminobenzoyldibutylaminopropanol;3-dibutylaminopropylp-aminobenzoate;3-Dibutylaminopropyl p-aminobenzoate;3-(Dibutylamino)propyl 4-aminobenzoate;3-(dibutylamino)propyl 4-azanylbenzoate;3-(dibutylamino)-1-propanolp-aminobenzoate
CBNumber
CB6261717
Molecular Formula
C18H30N2O2
Formula Weight
306.44
MOL File
149-16-6.mol
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BUTACAINE Property

Melting point:
25°C
Boiling point:
bp0.11 178-182°
Density 
1.0593 (rough estimate)
refractive index 
1.5700 (estimate)
storage temp. 
−20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
pKa 8.96 (Uncertain)
form 
Solid
color 
White to Pale Orange
Stability:
Light Sensitive
EPA Substance Registry System
Butacaine (149-16-6)
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Safety

RIDADR 
3249
WGK Germany 
3
RTECS 
UB0875000
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B694295
Product name
Butacaine
Packaging
1g
Price
$220
Updated
2021/12/16
TRC
Product number
B694295
Product name
Butacaine
Packaging
2.5g
Price
$440
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0015124
Product name
BUTACAINE
Purity
95.00%
Packaging
10MG
Price
$255.15
Updated
2021/12/16
Crysdot
Product number
CD31003361
Product name
Butacaine
Purity
98+%
Packaging
100mg
Price
$42
Updated
2021/12/16
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BUTACAINE Chemical Properties,Usage,Production

Originator

Butelline,ALK-Abello

Uses

radioopaque agent

Uses

Butacaine is an human glutathione transferase P1-1 (GST P1-1).

Definition

ChEBI: 4-aminobenzoic acid 3-(dibutylamino)propyl ester is a benzoate ester.

Manufacturing Process

40 g p-nitro-gamma-bromo-propylbenzoate and 40 g dibutylamine are heated together at 60°C, for four hours. The excess dibutyl amine is removed by washing the product with water and then steam distilling the residue. The material remaining in the flask is taken up in benzene and treated with aqueous hydrochloric acid. Part of the p-nitrobenzoyl-gamma-di-nbutylamminopropanol hydrochloride thus formed goes into the water layer, while most of it separates as a heavy oily layer. This, together with the water layer, is separated from the benzene layer, made alkaline, and the resulting base taken up in benzene. Upon removal of the solvent, the desired pnitrobenzoyl- gamma-di-n-butylamminopropanol is obtained.
The p-nitrobenzoyl-gamma-di-n-butylamminopropanol is reduced by warming to about 60°C with an excess of iron filings and a small amount of hydrochloric acid for four hours. The material is then allowed to cool, neutralized with dilute sodium hydroxide solution, and extracted with ether. Upon the removal of the ether, the free base, para-aminobenzoyl-gamma-din- butylaminopropanol, remains behind as an oil. It is exactly neutralized with aqueous hydrochloric acid and the resulting solid salt purified by recrystallization from water or a suitable organic solvent. It melts at 151°- 152°C (corr.) after drying at 100°C.

brand name

Butyn (Abbott).

Therapeutic Function

Local anesthetic

BUTACAINE Preparation Products And Raw materials

Raw materials

Preparation Products

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BUTACAINE Suppliers

MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15951
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30239
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58

149-16-6, BUTACAINERelated Search:


  • 1-Propanol, 3-(dibutylamino)-, 4-aminobenzoate
  • 1-Propanol, 3-(dibutylamino)-, 4-aminobenzoate (ester)
  • 1-Propanol, 3-(dibutylamino)-, p-aminobenzoate
  • 1-Propanol, 3-(dibutylamino)-, p-aminobenzoate (ester)
  • 3-(Dibutyamino)-1-propanol-p-aminobenzoate (ester)
  • 3-(dibutylamino)-1-propano4-aminobenzoate(ester)
  • 3-(Dibutylamino)-1-propanol p-aminobenzoate
  • 3-(dibutylamino)-1-propanolp-aminobenzoate
  • 3-(dibutylamino)-1-propanop-aminobenzoate(ester)
  • 3-(Dibutylamino)propyl 4-aminobenzoate
  • 3-(p-Aminobenzoxy)-1-di-n-butylaminopropane
  • 3-Dibutylaminopropyl p-aminobenzoate
  • Dibutylaminopropyl-p-aminobenzoate
  • PHENBUTACAINE
  • 4-Aminobenzoic acid 3-(dibutylamino)propyl
  • 4-Aminobenzoic acid 3-(dibutylamino)propyl ester
  • 3-(dibutylamino)propyl 4-azanylbenzoate
  • 3-dibutylaminopropylp-aminobenzoate
  • Butyn
  • p-Aminobenzoyldibutylaminopropanol
  • BUTACAINE
  • 1-Propanol, 3-(dibutylamino)-, 1-(4-aminobenzoate)
  • 149-16-6
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