BUTACAINE
- Product Name
- BUTACAINE
- CAS No.
- 149-16-6
- Chemical Name
- BUTACAINE
- Synonyms
- Butyn;BUTACAINE;PHENBUTACAINE;Dibutylaminopropyl-p-aminobenzoate;p-Aminobenzoyldibutylaminopropanol;3-dibutylaminopropylp-aminobenzoate;3-Dibutylaminopropyl p-aminobenzoate;3-(Dibutylamino)propyl 4-aminobenzoate;3-(dibutylamino)propyl 4-azanylbenzoate;3-(dibutylamino)-1-propanolp-aminobenzoate
- CBNumber
- CB6261717
- Molecular Formula
- C18H30N2O2
- Formula Weight
- 306.44
- MOL File
- 149-16-6.mol
BUTACAINE Property
- Melting point:
- 25°C
- Boiling point:
- bp0.11 178-182°
- Density
- 1.0593 (rough estimate)
- refractive index
- 1.5700 (estimate)
- storage temp.
- −20°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- pKa 8.96 (Uncertain)
- form
- Solid
- color
- White to Pale Orange
- Stability:
- Light Sensitive
- EPA Substance Registry System
- Butacaine (149-16-6)
Safety
- RIDADR
- 3249
- WGK Germany
- 3
- RTECS
- UB0875000
- HazardClass
- 6.1(b)
- PackingGroup
- III
N-Bromosuccinimide Price
- Product number
- B694295
- Product name
- Butacaine
- Packaging
- 1g
- Price
- $220
- Updated
- 2021/12/16
- Product number
- B694295
- Product name
- Butacaine
- Packaging
- 2.5g
- Price
- $440
- Updated
- 2021/12/16
- Product number
- API0015124
- Product name
- BUTACAINE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $255.15
- Updated
- 2021/12/16
- Product number
- CD31003361
- Product name
- Butacaine
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $42
- Updated
- 2021/12/16
BUTACAINE Chemical Properties,Usage,Production
Originator
Butelline,ALK-Abello
Uses
radioopaque agent
Uses
Butacaine is an human glutathione transferase P1-1 (GST P1-1).
Definition
ChEBI: 4-aminobenzoic acid 3-(dibutylamino)propyl ester is a benzoate ester.
Manufacturing Process
40 g p-nitro-gamma-bromo-propylbenzoate and 40 g dibutylamine are heated
together at 60°C, for four hours. The excess dibutyl amine is removed by
washing the product with water and then steam distilling the residue. The
material remaining in the flask is taken up in benzene and treated with
aqueous hydrochloric acid. Part of the p-nitrobenzoyl-gamma-di-nbutylamminopropanol
hydrochloride thus formed goes into the water layer,
while most of it separates as a heavy oily layer. This, together with the water
layer, is separated from the benzene layer, made alkaline, and the resulting
base taken up in benzene. Upon removal of the solvent, the desired pnitrobenzoyl-
gamma-di-n-butylamminopropanol is obtained.
The p-nitrobenzoyl-gamma-di-n-butylamminopropanol is reduced by warming
to about 60°C with an excess of iron filings and a small amount of
hydrochloric acid for four hours. The material is then allowed to cool,
neutralized with dilute sodium hydroxide solution, and extracted with ether.
Upon the removal of the ether, the free base, para-aminobenzoyl-gamma-din-
butylaminopropanol, remains behind as an oil. It is exactly neutralized with
aqueous hydrochloric acid and the resulting solid salt purified by
recrystallization from water or a suitable organic solvent. It melts at 151°-
152°C (corr.) after drying at 100°C.
brand name
Butyn (Abbott).
Therapeutic Function
Local anesthetic
BUTACAINE Preparation Products And Raw materials
Raw materials
Preparation Products
BUTACAINE Suppliers
- Tel
- 021-58955995
- Fax
- 609-228-5909
- sales@medchemexpress.cn
- Country
- United States
- ProdList
- 4863
- Advantage
- 58
- Tel
- 021-33632979
- Fax
- 021-34692979
- info@tsbiochem.com
- Country
- China
- ProdList
- 8073
- Advantage
- 58
- Tel
- +1-800-259-7612
- Fax
- +1-800-259-7612
- info@musechem.com
- Country
- United States
- ProdList
- 4662
- Advantage
- 60
- Tel
- 025-58851090 13611564524
- Fax
- (6)02557626880
- lwan@aikonchem.com
- Country
- China
- ProdList
- 15952
- Advantage
- 58
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19892
- Advantage
- 58
- Tel
- 86-571-88216897,88216896 13588875226
- Fax
- 86-571-88216895
- sales@hzclap.com
- Country
- CHINA
- ProdList
- 6313
- Advantage
- 58
- Tel
- +86-0371-86658258 15093356674;
- Fax
- 0371-86658258
- laboratory@coreychem.com
- Country
- China
- ProdList
- 30255
- Advantage
- 58
- Tel
- 18871490254
- Fax
- 027-59599243
- linda@hubeijusheng.com
- Country
- CHINA
- ProdList
- 28180
- Advantage
- 58
- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
- Country
- China
- ProdList
- 11289
- Advantage
- 58
- Tel
- 88888888888
- hongquchem@qq.com
- Country
- China
- ProdList
- 5132
- Advantage
- 58