ChemicalBook > CAS DataBase List > 4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester

4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester

Product Name
4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester
CAS No.
133284-74-9
Chemical Name
4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester
Synonyms
Loratadine impurity A;Loratadine EP Impurity 1;Loratadine impurity-F(USP);Loratadine Impurity A（EP ）;11-Hydroxy Dihydro Loratadine;Ethyl 4-[(11RS)-8-Chloro-11-hydroxy;Loratadine EP Impurity A ( USP RC F);Loratadine Impurity 1(Loratadine EP Impurity A);Loratidine EP Impurity A/ Loratidine Related Compound F;Loratadine Impurity 1/Loratadine EP Impurity A/11-Hydroxy Dihydroloratadine
CBNumber
CB62622192
Molecular Formula
C22H25ClN2O3
Formula Weight
400.9
MOL File
133284-74-9.mol
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4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester Property

Melting point:
>52°C (dec.)
Boiling point:
545.1±50.0 °C(Predicted)
Density 
1.294
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Ethanol (Slightly)
pka
12.23±0.20(Predicted)
form 
Solid
color 
White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
H941370
Product name
11-HydroxyDihydroLoratadine
Packaging
50mg
Price
$125
Updated
2021/12/16
Usbiological
Product number
279080
Product name
11-Hydroxy dihydro loratadine
Packaging
100mg
Price
$420
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
46596
Product name
11-HydroxyDihydroLoratadine
Packaging
100mg
Price
$390
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0294211
Product name
LORATADINE EP IMPURITY F
Purity
95.00%
Packaging
1MG
Price
$739.2
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0294211
Product name
LORATADINE EP IMPURITY F
Purity
95.00%
Packaging
10MG
Price
$1871.1
Updated
2021/12/16
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4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester Chemical Properties,Usage,Production

Uses

11-Hydroxy Dihydroloratadine (Loratadine EP Impurity A; Loratadine USP Related Compound F) is an impurity of Loratadine (L469575).

Uses

11-Hydroxy Dihydroloratadine is an impurity of Loratadine (L469575).

4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester Suppliers

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133284-74-9, 4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl EsterRelated Search:

Desloratadine N-Hydroxypiperidine N-ForMyl Desloratadine 8-Dechloro-7-chloro Loratadine Loratadine Impurity 15 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Loratadine Impurity 13 Loratadine Impurity 13 Loratadine Impurity 17 3-Hydroxy loratadine 8-Dechloro-10-chloro Loratadine Loratadine Loratadine 2-Chloro IMpurity N-Methyl Desloratadine 4-chloro-loratadine Loratadine EP Impurity E 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one N-Carbethoxy-4-piperidone Desloratadine

  • 11-Hydroxy Dihydro Loratadine
  • 4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester
  • ethyl 4-(8-chloro-11-hydroxy-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-yl)piperidine-1-carboxylate
  • Loratadine Impurity 1/Loratadine EP Impurity A/11-Hydroxy Dihydroloratadine
  • Loratadine impurity-F(USP)
  • 1-Piperidinecarboxylic acid, 4-(8-chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-, ethyl ester
  • Loratadine impurity A
  • Loratadine EP Impurity A ( USP RC F)
  • 8-Chloro-6,11-dihydro-11-[N-ethoxycarbonyl-4-piperidinyl]-11-hydroxy-5H-benzo[5,6] cyclohepta[1,2-b]pyridine
  • Loratadine Impurity 1(Loratadine EP Impurity A)
  • Ethyl 4-[(11RS)-8-Chloro-11-hydroxy
  • Ethyl 4-((11RS)-8-chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperid
  • ethyl 4-(8-chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate
  • Loratidine EP Impurity A/ Loratidine Related Compound F
  • Loratadine Impurity A（EP ）
  • Ethyl 4-(8-chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate (Loratadine Impurity)
  • Loratadine EP Impurity 1
  • 133284-74-9
  • Amines
  • Heterocycles
  • Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Amines, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals