ALK inhibitor 2

Product Name: ALK inhibitor 2
CAS No.: 761438-38-4
Chemical Name: ALK inhibitor 2
Synonyms: ALK inhibitor 2;2-[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-;2-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide;2-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzenesulfonamide;2-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methylbenzenesulfonamide;BenzenesulfonaMide, 2-[[5-chloro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-4-pyriMidinyl]aMino]-N-Methyl-;ALK tyrosine kinase receptor,kinase,Anaplastic lymphoma kinase (ALK),Anaplastic lymphoma kinase,CD246,testis-specific,ALK inhibitor 2,serine/threonine,adhesion,Inhibitor,focal,PTK2 protein tyrosine kinase 2,PTK2,contraception,Cluster of differentiation 246,reversible,ALK inhibitor-2,ALK inhibitor2,inhibit,FAK,Focal adhesion kinase,TSSK2,male
CBNumber: CB62624075
Molecular Formula: C23H28ClN7O3S
Formula Weight: 518.03
MOL File: 761438-38-4.mol

More

Less

ALK inhibitor 2 Property

Boiling point:: 712.4±70.0 °C(Predicted)
Density: 1.371±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
pka: 11.27±0.10(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0796
Product name: ALKinhibitor2
Purity: 99.77%
Packaging: 5mg
Price: $307
Updated: 2021/12/16

ApexBio Technology

Product number: A3155
Product name: ALKinhibitor2
Packaging: 5mg
Price: $375
Updated: 2021/12/16

ChemScene

Product number: CS-0796
Product name: ALKinhibitor2
Purity: 99.77%
Packaging: 10mg
Price: $430
Updated: 2021/12/16

ApexBio Technology

Product number: A3155
Product name: ALKinhibitor2
Packaging: 10mg
Price: $524
Updated: 2021/12/16

Ambeed

Product number: A524942
Product name: ALKinhibitor2
Purity: 98+%
Packaging: 250mg
Price: $576
Updated: 2021/12/16

More

Less

ALK inhibitor 2 Chemical Properties,Usage,Production

Biological Activity

ALK inhibitor 2 (compound 18) is a potent, pyrimidine ALK inhibitor. It is a potent testis-specific serine/threonine kinase 2 (TSSK2; IC50=37 nM) and focal adhesion kinase (FAK; IC50=5 nM) inhibitor.

in vitro

Testis-specific serine/threonine kinase 2 (TSSK2) is an important target for reversible male contraception. ALK inhibitor 2 (compound 18) contains a methylpiperazine A ring (R1=Me, X=N) and a D ring with R5=methylsulfonamide. ALK inhibitor 2 can undergo metabolic oxidation to form reactive adducts in the presence of glutathione.

target

IC50: 37 nM (TSSK2) and 5 nM (FAK)

ALK inhibitor 2 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

ALK inhibitor 2 Suppliers

China 57 United States 12 Global 69

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
Advantage: 58

ShangHai KenEn Chemical Technology Co., Ltd.

Tel: 13120367189
Fax: 021-50315529
Email: mychess007@163.com
Country: China
ProdList: 1994
Advantage: 55

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2989
Advantage: 60

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 990
Advantage: 55

Guangzhou Zhiya Chemdrugs Co.,Ltd

Tel: 18122150900
Fax: QQ:2869377561
Email: sculk28@163.com
Country: China
ProdList: 647
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9254
Advantage: 55

761438-38-4, ALK inhibitor 2Related Search:

CHLOROMETHYL(DIMETHYL)METHOXYSILANE

ALK inhibitor 2

BenzenesulfonaMide, 2-[[5-chloro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-4-pyriMidinyl]aMino]-N-Methyl-

2-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methylbenzenesulfonamide

2-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide

2-[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-

2-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzenesulfonamide

ALK tyrosine kinase receptor,kinase,Anaplastic lymphoma kinase (ALK),Anaplastic lymphoma kinase,CD246,testis-specific,ALK inhibitor 2,serine/threonine,adhesion,Inhibitor,focal,PTK2 protein tyrosine kinase 2,PTK2,contraception,Cluster of differentiation 246,reversible,ALK inhibitor-2,ALK inhibitor2,inhibit,FAK,Focal adhesion kinase,TSSK2,male

761438-38-4

C23H28ClN7O3S

Inhibitors