HIV-1 integrase inhibitor
- Product Name
- HIV-1 integrase inhibitor
- CAS No.
- 544467-07-4
- Chemical Name
- HIV-1 integrase inhibitor
- Synonyms
- HIV-1 integrase inhibitor;HIV-1 integrase inhibitor USP/EP/BP;HIV 1 integrase inhibitor,HIV1 integrase inhibitor;4-[3-(Azidomethyl)phenyl]-2-hydroxy-4-oxo-2-butenoic acid;(Z)-4-(3-(azidoMethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid
- CBNumber
- CB62624181
- Molecular Formula
- C11H9N3O4
- Formula Weight
- 247.21
- MOL File
- 544467-07-4.mol
HIV-1 integrase inhibitor Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Powder
- color
- Light yellow to yellow
N-Bromosuccinimide Price
- Product number
- A3461
- Product name
- HIV-1integraseinhibitor
- Packaging
- 5mg
- Price
- $551
- Updated
- 2021/12/16
- Product number
- INB0001403
- Product name
- (Z)-4-(3-(AZIDOMETHYL)PHENYL)-2-HYDROXY-4-OXOBUT-2-ENOIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $765.23
- Updated
- 2021/12/16
- Product number
- A3461
- Product name
- HIV-1integraseinhibitor
- Packaging
- 10mg
- Price
- $866
- Updated
- 2021/12/16
- Product number
- INB0001403
- Product name
- (Z)-4-(3-(AZIDOMETHYL)PHENYL)-2-HYDROXY-4-OXOBUT-2-ENOIC ACID
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1065.66
- Updated
- 2021/12/16
- Product number
- INB0001403
- Product name
- (Z)-4-(3-(AZIDOMETHYL)PHENYL)-2-HYDROXY-4-OXOBUT-2-ENOIC ACID
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1295.03
- Updated
- 2021/12/16
HIV-1 integrase inhibitor Chemical Properties,Usage,Production
Uses
HIV-1 integrase inhibitor is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
target
HIV-1 integrase
IC 50
HIV-1
References
[1] Hobaika, Z.; Zargarian, L.; Maroun, R. G.; Mauffret, O.; Burke, T. R., Jr.; Fermandjian, S. HIV-1 Integrase and Virus and Cell DNAs: Complex Formation and Perturbation by Inhibitors of Integration. Neurochemical Research (2010), 35(6), 888-893. DOI:10.1007/s11064-009-0098-2
[2] Loizidou, Eriketi Z.; Zeinalipour-Yazdi, Constantinos D.; Christofides, Tasos; Kostrikis, Leondios G. Analysis of binding parameters of HIV-1 integrase inhibitors: Correlates of drug inhibition and resistance. Bioorganic & Medicinal Chemistry (2009), 17(13), 4806-4818.
[3] Kawasuji T.Carbamoyl Pyridone HIV-1 Integrase Inhibitors. 1. Molecular Design and Establishment of an Advanced Two-Metal Binding Pharmacophore.J Med Chem. 2012 Sep 10. DOI:10.1021/jm3010459
[4] Yan A, Xuan S, Hu X.Classification of Active and Weakly Active ST Inhibitors of HIV-1 Integrase Using a Support Vector Machine.Comb Chem High Throughput Screen. 2012 Aug 28. DOI:10.2174/138620712803901108
[5] Yu S, Zhao G.Development of Polyphenols as HIV-1 Integrase Inhibitors: A Summary and Perspective.Curr Med Chem. 2012 Aug 27. DOI:10.2174/092986712803833236
HIV-1 integrase inhibitor Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from HIV-1 integrase inhibitor manufacturers
- Product
- HIV-1 integrase inhibitor 544467-07-4
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2019-12-25